{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:34:12Z","timestamp":1787070852789,"version":"build-2736575974"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Multiple sclerosis (MS) is a chronic neurological disease that progresses with crisis and remission and causes significant psychosocial problems. Fatigue and sleep disorders are reported to be the most frequent problems that could change by gender and potentially affect daily living activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aimed to examine the effects of pain, fatigue, and sleep quality on the activities of daily living in patients with multiple sclerosis by gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study involved 188 patients with MS. G*Power 3.4.9 was used in the study sample estimation, and it was found that at least 111 women and 45 men individuals should be reached with 0.5 (medium) effect size, 80% power, 5% type I error, and 2.5 allocation ratio. Considering 10% data loss, the study was completed with 188 multiple sclerosis patients, 134 women and 54 men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      PwMS\u2019s pain, fatigue, sleep, and daily living activities were compared according to gender; it was found that the difference in the mean scores of women\u2019s PSQI subdimension \u201chabitual sleep efficiency\u201d was statistically significantly higher than that of men\u2019s (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). A negative correlation was found between FIS scores and NEADL total scores and subdimension scores in men and women with MS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). In women with MS, the degree of fatigue being \u201cimportant\u201d (9.184 units) and \u201cvery important\u201d (7.893 units) reduces daily living activities. In men with MS, \u201cpoor sleep quality\u201d reduces activities of daily living (11.559 units).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>According to gender, women\u2019s DLA was negatively affected by fatigue, while men\u2019s DLA was negatively affected by poor sleep quality. Therefore, increased sleep disorders in men and fatigue in women may cause a decrease in daily life activities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_487_24","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T02:00:46Z","timestamp":1742176846000},"page":"91-98","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of Pain, Fatigue, and Sleep Quality on Activities of Daily Living in Patients with Multiple Sclerosis by Gender: A Descriptive Study from Turkey"],"prefix":"10.4103","volume":"28","author":[{"given":"Z","family":"Eskimez","sequence":"first","affiliation":[{"name":"Internal Medicine Nursing Department, Dr. \u00c7ukurova University, Faculty of Health Sciences, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PY","family":"Demirci","sequence":"additional","affiliation":[{"name":"Internal Medicine Nursing Department, Dr. \u00c7ukurova University, Faculty of Health Sciences, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SB","family":"Ye\u015filot","sequence":"additional","affiliation":[{"name":"Psychiatric Nursing Department, Dr. \u00c7ukurova University, Faculty of Health Sciences, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,17]]},"reference":[{"key":"R1-20260423","doi-asserted-by":"crossref","first-page":"37","DOI":"10.34172\/icnj.2021.08","article-title":"Effectiveness of groupt herapy based on acceptance and commitment on the severity of fatigue and depression with the moderating role of alexithymia in patients with multiple sclerosis","volume":"8","author":"Haji Seyed Javadi","year":"2020","journal-title":"Int Clin Neurosci J"},{"key":"R2-20260423","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/jnr.23955","article-title":"The importance of studying sex differences in disease: The example of multiple sclerosis","volume":"95","author":"Golden","year":"2017","journal-title":"J Neurosci Res"},{"key":"R3-20260423","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4274\/tnd.2020.36418","article-title":"Epidemiology of multiple sclerosis in Turkey; a ten- year trend in rural cities","volume":"27","author":"B\u00f6l\u00fck","year":"2021","journal-title":"Turk J Neurol"},{"key":"R4-20260423","first-page":"102","article-title":"Multiple sclerosis in the Faroe Islands. 8. 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