{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:10:14Z","timestamp":1793214614962,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aim:<\/jats:title>\n This study aimed to profile the clinical features and demographics of patients with endophthalmitis in a tertiary care center, Western region, Saudi Arabia. We used a retrospective cross-sectional case series at King Abdulaziz University Hospital.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n Endophthalmitis was diagnosed in a total of 14 eyes of 14 patients treated in our hospital between 2002 and 2018. The patients' medical records were reviewed to gather demographic and clinical data.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The mean age of patients was 52.8 \u00b1 19.2 years, and 50% of patients were male. The majority of endophthalmitis cases were post-ophthalmic surgery (50%), 35.7% were of endogenous origin, 7.2% were associated with corneal ulcer with perforation, and 7.2% were post open globe injury. Patients' admission to the hospital ranged from 2 to 10 days from symptoms occurrence with a median of 5 days. Half of the patients presented with no light perception vision, counting fingers in 14.2%, hand motion in 14.2%, light perception in 7.2%, and 20\/300 in 7.2%. The final visual outcome improved in four cases (28.5%) with best corrected visual acuity of 20\/40 reached in one patient.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Post- ophthalmic surgery and endogenous endophthalmitis were the most common causes of endophthalmitis among our patients, with late presentation to the hospital and poor vision at presentation also being common findings. These findings highlight the necessity of proper patient education, after care and adherence to sterile techniques in ensuring that patients recover successfully from ophthalmic surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/njcp.njcp_514_20","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T02:18:50Z","timestamp":1641867530000},"page":"1527-1530","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Clinical profile of patients with endophthalmitis"],"prefix":"10.4103","volume":"24","author":[{"given":"N","family":"Almarzouki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Alessa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Raffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-17-20240907","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/eye.2010.145","article-title":"Endogenous endophthalmitis: 10-year experience at a tertiary referral centre","volume":"25","author":"Connell","year":"2011","journal-title":"Eye"},{"key":"R2-17-20240907","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3341\/kjo.2017.0036","article-title":"Endophthalmitis","volume":"31","author":"Sheu","year":"2017","journal-title":"Korean J Ophthalmol"},{"key":"R3-17-20240907","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/infdis\/162.1.115","article-title":"The clinical spectrum of endophthalmitis: Incidence, predisposing factors, and features influencing outcome","volume":"162","author":"Shrader","year":"1990","journal-title":"J Infect Dis"},{"key":"R4-17-20240907","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1442-9071.2008.01813.x","article-title":"Infectious endophthalmitis: Clinical features, management and visual outcomes","volume":"36","author":"Fan","year":"2008","journal-title":"Clin Exp Ophthalmol"},{"key":"R5-17-20240907","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.4103\/0366-6999.235866","article-title":"Clinical analysis of 1593 patients with infectious endophthalmitis: A 12-year study at a tertiary referral center in Western China","volume":"131","author":"Yang","year":"2018","journal-title":"Chin Med J"},{"key":"R6-17-20240907","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3129\/i08-160","article-title":"Incidence and outcome of endophthalmitis over a 13-year period","volume":"44","author":"Krause","year":"2009","journal-title":"Can J Ophthalmol"},{"key":"R7-17-20240907","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1177\/112067210901900519","article-title":"Incidence, clinical features, causative organisms, and visual outcomes of delayed-onset pseudophakic endophthalmitis","volume":"19","author":"Al-Mezaine","year":"2009","journal-title":"Eur J Ophthalmol"},{"key":"R8-17-20240907","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4103\/0974-9233.171756","article-title":"Incidence of endophthalmitis after intravitreal anti-vascular endothelial growth factor: Experience in Saudi Arabia","volume":"23","author":"Al-Rashaed","year":"2016","journal-title":"Middle East Afr J Ophthalmol"},{"key":"R9-17-20240907","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.sjopt.2014.11.001","article-title":"Incidence of endophthalmitis following intravitreal Bevacizumab injection at a tertiary care hospital in Eastern Province of Saudi Arabia","volume":"29","author":"Cheema","year":"2015","journal-title":"Saudi J Ophthalmol"},{"key":"R10-17-20240907","first-page":"91","article-title":"Endophthalmitis patients seen in a tertiary eye care centre in Odisha: A clinico-microbiological analysis","volume":"139","author":"Sharma","year":"2014","journal-title":"Indian J Med Res"},{"key":"R11-17-20240907","first-page":"247","article-title":"Infectious endophthalmitis: Review of 420 cases","volume":"7","author":"Bhoomibunchoo","year":"2013","journal-title":"Clin Ophthalmol"},{"key":"R12-17-20240907","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jcrs.2012.10.037","article-title":"Six-year incidence of endophthalmitis after cataract surgery: Swedish national study","volume":"39","author":"Friling","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"R13-17-20240907","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ophtha.2008.09.039","article-title":"Risk factors for acute endophthalmitis after cataract surgery: A population-based study","volume":"116","author":"Hatch","year":"2009","journal-title":"Ophthalmology"},{"key":"R15-17-20240907","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3341\/jkos.2013.54.7.1025","article-title":"Factors affecting final visual acuity in infectious endophthalmitis following cataract surgery","volume":"54","author":"Kang","year":"2013","journal-title":"J Korean Ophthalmol Soc"},{"key":"R16-17-20240907","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/0974-9233.154397","article-title":"Incidence and determinants of endophthalmitis within 6 months of surgeries over a 2-year period at King Khaled Eye Specialist Hospital, Saudi Arabia: A review","volume":"22","author":"Khandekar","year":"2015","journal-title":"Middle East Afr J Ophthalmol"},{"key":"R17-17-20240907","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.ajo.2009.09.021","article-title":"Acute endophthalmitis after cataract surgery: 250 consecutive cases treated at a tertiary referral center in the Netherlands","volume":"149","author":"Pijl","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"R18-17-20240907","doi-asserted-by":"crossref","first-page":"208","DOI":"10.3928\/1542-8877-20010501-06","article-title":"Risk factors in endophthalmitis leading to evisceration or enucleation","volume":"32","author":"Tsai","year":"2001","journal-title":"Ophthalmic Surg Lasers"},{"key":"R19-17-20240907","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s10792-007-9068-3","article-title":"Retrospective analysis of etiopathogenesis of all cases of endophthalmitis at a large tertiary referral center","volume":"27","author":"Karacal","year":"2007","journal-title":"Int Ophthalmol"},{"key":"R20-17-20240907","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1177\/112067210601600217","article-title":"Did the spectrum of endophthalmitis change? A study comprising 13 years experience with operative therapy of endophthalmitis","volume":"16","author":"Janknecht","year":"2006","journal-title":"Eur J Ophthalmol"},{"key":"R21-17-20240907","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1136\/bjo.81.9.719","article-title":"Assessment of a standard treatment protocol on visual outcome following presumed bacterial endophthalmitis","volume":"81","author":"Okhravi","year":"1997","journal-title":"Br J Ophthalmol"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_514_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:54:03Z","timestamp":1787756043000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_514_20"}},"subtitle":["A 16- year retrospective, cross-sectional study at tertiary care hospital in Western Saudi Arabia"],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_514_20","relation":{},"ISSN":["1119-3077"],"issn-type":[{"value":"1119-3077","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}