{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:36:04Z","timestamp":1786649764956,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"\n Background:<\/jats:title>\n Infants should be provided with effective feeding skills with evidence-based care practices to ensure nutritional tolerance and maximize the growth and development in preterm infants.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n \n This study aimed to examine the effects of \u201coral administration of breast milk droplets\u201d and \u201cpalatal stimulation with a finger\u201d methods on feed tolerance in preterm newborns fed via an orogastric tube\n .<\/jats:italic>\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n This randomized controlled trial was conducted in the neonatal intensive care unit of a private hospital. The study included 90 premature newborns born at the 28\n th<\/jats:sup>\n \u201336\n th<\/jats:sup>\n gestational weeks and admitted to intensive care. We applied breast milk droplets inside the oral cavity of newborns (30) in one of the intervention groups and stimulated the palate of newborns (30) by using a finger in the other. We performed these interventions every 3 hours for 5 minutes at the feeding times of the newborns for 7 days. Babies in the control group were not applied any intervention. We used SPSS (Statistical Package for Social Sciences) 22.0 for Windows software for statistical analyses.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The number of defecations, frequencies of residuals, body weight, and abdominal circumference were significantly different between the groups (\n P<\/jats:italic>\n < 0.05). The increments in body weight and reductions in abdominal circumference were significantly different between the groups in the study (\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Palatal stimulation with a finger acted on feed tolerance more favorably than the oral administration of breast milk droplets or no intervention in preterm infants fed via OGT. We suggest primarily that palatal stimulation with a finger and secondarily the oral administration of breast milk droplets as the two methods to be employed to overcome feeding intolerance, which is a significant problem in premature infants.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/njcp.njcp_558_24","type":"journal-article","created":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T23:00:09Z","timestamp":1745794809000},"page":"452-460","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["The Effects of \u201cOral Administration of Breast Milk Droplets\u201d and \u201cPalatal Stimulation with a Finger\u201d Methods on Feed Tolerance in Preterm Newborns Fed via an Orogastric Tube: Randomized Controlled Trial"],"prefix":"10.4103","volume":"28","author":[{"given":"C","family":"Tun\u00e7","sequence":"first","affiliation":[{"name":"Istanbul Medipol University, Institute of Health Science, Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A Kokcu","family":"Dogan","sequence":"additional","affiliation":[{"name":"Istanbul Medipol University, Institute of Health Science, Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,26]]},"reference":[{"key":"R2-20260423","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.clnu.2019.03.026","article-title":"Definitions, predictors and outcomes of feeding intolerance in critically ill children: A systematic review","volume":"39","author":"Eveleens","year":"2020","journal-title":"Clin Nutr"},{"key":"R3-20260423","first-page":"45","article-title":"Application of prolonging small feeding volumes early in life to prevent of necrotizing enterocolitis in very low birth weight preterm infants","volume":"3","author":"Li","year":"2016","journal-title":"Int J Nurs Sci"},{"key":"R4-20260423","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1021\/pr1009367","article-title":"Evolutionaryglycomics: Characterization of milk oligosaccharides in primates","volume":"10","author":"Tao","year":"2011","journal-title":"J Proteome Res"},{"key":"R5-20260423","doi-asserted-by":"crossref","first-page":"423","DOI":"10.3390\/nu7010423","article-title":"Guidelines for feeding very low birth weight infants","volume":"7","author":"Dutta","year":"2015","journal-title":"Nutrients"},{"key":"R6-20260423","first-page":"CD001819","article-title":"Continuous nasogastric milk feeding versus intermittent bolus milk feeding for premature infants less than 1500 grams","volume":"2011","author":"Premji","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"R7-20260423","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/ejp.757","article-title":"Epidemiology of painful procedures performed in neonates: A systematic review of observational studies","volume":"20","author":"Cruz","year":"2016","journal-title":"Eur J Pain"},{"key":"R8-20260423","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1001\/archpedi.157.11.1058","article-title":"Do we still hurt newborn babies? 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