{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:41Z","timestamp":1786650041324,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"\n Background:<\/jats:title>\n Gastrografin\u00ae (GG) is a water-soluble contrast agent. Besides its role in diagnosing small bowel obstruction (SBO), its effectiveness in treating adhesive small bowel obstruction (ASBO) has been suggested.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n A retrospective study was performed at our institution to observe whether patients receiving GG benefited from the intervention compared to patients receiving standard treatment of SBO.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Administration of GG was the surgeon\u2019s decision, as was the decision for operative treatment. No treatment protocols were used at the department regarding GG use. The observed variables were length of hospital stay (LoHS), operative rate, and mortality rate.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Results of our study confirmed a substantial diagnostic value of GG challenge; passage of GG to the large bowel indicates successful conservative treatment of SBO. We observed that patients receiving GG (GG+) at our department did not have a significantly lower LoHS or mortality rate than those not receiving GG (GG-). However, GG+ did have a lower mean LoHS and a lower mean mortality rate than GG- group. The GG+ group displayed a significantly lower operative rate. Based on the design of our study, this cannot be attributed to the therapeutic effect of GG but rather to the selective treatment of patients.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The GG challenge is a solid diagnostic tool, indicating a successful resolution of SBO if the passage of the contrast to the large bowel can be demonstrated. Although our study results point towards its positive effect, we cannot confirm the therapeutic function of GG due to probable treatment bias in severely affected patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/njcp.njcp_561_23","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T08:00:28Z","timestamp":1744358428000},"page":"339-343","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Gastrografin\u00ae Use and Its Benefits in Small Bowel Obstruction \u2013 A Single-Center Retrospective Study"],"prefix":"10.4103","volume":"28","author":[{"given":"N","family":"Arslani","sequence":"first","affiliation":[{"name":"Department of Abdominal and General Surgery, University Medical Center Maribor, Slovenia"},{"name":"Department of Surgery, Faculty of Medicine, University of Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"R1-20260423","doi-asserted-by":"crossref","first-page":"404","DOI":"10.5811\/westjem.2011.3.2175","article-title":"Ileus and small bowel obstruction in an emergency department observation unit: Are there outcome predictors?","volume":"12","author":"Dorsey","year":"2011","journal-title":"West J Emerg Med"},{"key":"R2-20260423","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.amjsurg.2018.12.063","article-title":"This too shall pass: Standardized Gastrografin protocol for partial small bowel obstruction","volume":"217","author":"Long","year":"2019","journal-title":"Am J Surg"},{"key":"R3-20260423","doi-asserted-by":"crossref","first-page":"432","DOI":"10.3748\/wjg.v13.i3.432","article-title":"Acute mechanical bowel obstruction: Clinical presentation, etiology, management and outcome","volume":"13","author":"Markogiannakis","year":"2007","journal-title":"World J Gastroenterol"},{"key":"R4-20260423","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.surg.2021.03.008","article-title":"Timing of Gastrografin administration in the management of adhesive small bowel obstruction (ASBO): Does it matter?","volume":"170","author":"Cohen","year":"2021","journal-title":"Surgery"},{"issue":"5 Suppl 4","key":"R5-20260423","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/TA.0b013e31827019de","article-title":"Evaluation and management of small-bowel obstruction: An Eastern Association for the Surgery of Trauma practice management guideline","volume":"73","author":"Maung","year":"2012","journal-title":"J Trauma Acute Care Surg"},{"key":"R6-20260423","first-page":"CD004651","article-title":"Oral water soluble contrast for the management of adhesive small bowel obstruction","volume":"2007","author":"Abbas","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"R7-20260423","doi-asserted-by":"crossref","first-page":"3742","DOI":"10.3748\/wjg.v11.i24.3742","article-title":"Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: A prospective evaluation","volume":"11","author":"Choi","year":"2005","journal-title":"World J Gastroenterol"},{"key":"R8-20260423","first-page":"1315","article-title":"Use of water-soluble contrast medium (gastrografin) does not decrease the need for operative intervention nor the duration of hospital stay in uncomplicated acute adhesive small bowel obstruction? A multicenter, randomized, clinical trial (Adhesive Small Bowel Obstruction Study) and systematic review","volume":"161","author":"Scott\u00e9","year":"2017","journal-title":"Surgery (United States)"},{"key":"R9-20260423","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jss.2020.06.053","article-title":"Optimal timing of first abdominal radiography after gastrografin administration for small bowel obstruction","volume":"256","author":"Alnachoukati","year":"2020","journal-title":"J Surg Res"},{"key":"R10-20260423","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jss.2009.03.092","article-title":"Clinical impacts of oral gastrografin follow-through in adhesive small bowel obstruction (SBO)","volume":"162","author":"Farid","year":"2010","journal-title":"J Surg Res"},{"key":"R11-20260423","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1503\/cjs.024009","article-title":"Impact of Gastrografin in clinical practice in the management of adhesive small bowel obstruction","volume":"54","author":"Srinivasa","year":"2011","journal-title":"Can J Surg"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_561_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:01:23Z","timestamp":1786647683000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_561_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_561_23","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"2023-07-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}