{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:29Z","timestamp":1786650029519,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>\n                    Immune thrombocytopenic purpura (ITP) is an autoimmune hematological disorder characterized by mucocutaneous bleeding. Although patients usually suffer from mild mucosal bleeding, visceral bleeding may occur depending on the severity of thrombocytopenia. Therefore, early diagnosis and treatment are of vital importance. In this case report, the diagnosis and treatment process of a patient diagnosed with ITP following acute oral bleeding will be presented. A 38-year-old male patient presented to the dentist with severe gingival bleeding for 2 days. Intraoral and extraoral examinations revealed spontaneous gingival bleeding, hemorrhagic bullae, and purpura. The patient was immediately referred to hematology with a prediagnosis of severe thrombocytopenia and laboratory investigations revealed a platelet count of 2.000\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Treatment was started for the patient who had a high risk of life-threatening bleeding. After treatment, the patient\u2019s platelet count improved and all lesions healed. The high potential of early signs of ITP in the intraoral region makes it necessary for dentists to have knowledge about the mechanism and clinical manifestations of this disease. In this case report, the importance of dentists\u2019 awareness of hematological diseases such as ITP in the early diagnosis of the disease and the prevention of possible complications are emphasized.\n                  <\/jats:p>","DOI":"10.4103\/njcp.njcp_579_24","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T02:01:19Z","timestamp":1743040879000},"page":"261-264","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Immune Thrombocytopenic Purpura Detected as a Result of Dental Examination: A Case Report"],"prefix":"10.4103","volume":"28","author":[{"given":"G","family":"Ertas","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Kirikkale University Faculty of Dentistry, Yahsihan, Kirikkale, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"M\u0131s\u0131rl\u0131oglu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Kirikkale University Faculty of Dentistry, Yahsihan, Kirikkale, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"key":"R1-20260423","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3390\/dj9090108","article-title":"Oral healthcare and idiopathic thrombocytopenic purpura: Early recognition, dental management and case report","volume":"9","author":"Lanza","year":"2021","journal-title":"Dent J"},{"key":"R2-20260423","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1007\/s12325-015-0251-z","article-title":"Current management of primary immune thrombocytopenia","volume":"32","author":"Provan","year":"2015","journal-title":"Adv Ther"},{"key":"R3-20260423","doi-asserted-by":"crossref","first-page":"410","DOI":"10.4103\/0976-237X.137976","article-title":"Idiopathic thrombocytopenic purpura","volume":"5","author":"Kayal","year":"2014","journal-title":"Contemp Clin Dent"},{"key":"R4-20260423","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41182-020-00248-1","article-title":"Dengue hemorrhagic fever as a rare cause of chronic \u0131mmune thrombocytopenic purpura. A pediatric case report","volume":"48","author":"Thadchanamoorthy","year":"2020","journal-title":"Trop Med Health"},{"key":"R5-20260423","first-page":"273","article-title":"Idiopathic thrombocytopenic purpura (ITP). New era for an old disease","volume":"57","author":"Onis\u00e2i","year":"2019","journal-title":"Rom J Intern Med"},{"key":"R6-20260423","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40902-018-0178-9","article-title":"Life-threating outcomes after dental implantation in patient with idiopathic thrombocytopenic purpura: A case report and review of literature","volume":"40","author":"Lee","year":"2018","journal-title":"Maxillofac Plast Reconstr Surg"},{"key":"R7-20260423","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/ajh.26045","article-title":"Immune thrombocytopenia (ITP) World Impact Survey: Patient and physician perceptions of diagnosis, signs and symptoms, and treatment","volume":"96","author":"Cooper","year":"2021","journal-title":"Am J Hematol"},{"key":"R8-20260423","doi-asserted-by":"crossref","first-page":"164.","DOI":"10.2174\/1874210601408010164","article-title":"Immune thrombocytopenic purpura presenting as unprovoked gingival hemorrhage: A case report","volume":"8","author":"Bal","year":"2014","journal-title":"Open Dent J"},{"key":"R9-20260423","first-page":"e49313","article-title":"Idiopathic thrombocytopenic purpura: Current limitations and management","volume":"15","author":"Thakre","year":"2023","journal-title":"Cureus"},{"key":"R10-20260423","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/jth.13940","article-title":"The association between idiopathic thrombocytopenic purpura and cardiovascular disease: A retrospective cohort study","volume":"16","author":"Chandan","year":"2018","journal-title":"J Thromb Haemost"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_579_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:01:13Z","timestamp":1786647673000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_579_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_579_24","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-08-31","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}