{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:35:02Z","timestamp":1787762102302,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim:<\/jats:title>\n                    <jats:p>There are criteria that include many organ systems to predict the prognosis in acute pancreatitis (AP) patients. In this study, we aimed to show how the course of the disease changes according to the Balthazar classification in AP patients presenting with renal failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials:<\/jats:title>\n                    <jats:p>\n                      Our study included 352 patients who were admitted to the Emergency Service of our hospital and were diagnosed and hospitalized with AP. According to the Balthazar score, patients with scores of 0\u20132, 4\u20136, and 8\u201310 were evaluated as mild, moderate, and severe AP, respectively. Demographic data (age, gender) of all patients were documented. The etiology of AP was determined in all patients. Biliary, drug\/toxic, alcohol, infections, hyperlipidemia, post-endoscopic retrograde cholangiopancreatography (ERCP), genetics, hypercalcemia, structural anomalies, and malignancy were evaluated as the etiology. Those without any underlying pathology were evaluated as idiopathic AP. The patients were divided into two groups as those with and without renal insufficiency. All patients underwent helical computed tomography (section 64, Aquilion; Toshiba Medical Systems, Tokyo) within the first 12 hours and between days 3 and 7. Pancreas, peripancreatic and extrapancreatic findings, and complications were examined. \u201cThe Statistical Package for the Social Sciences 19.0 (SPSS Armonk, NY: IBM Corp.)\u201d was used for all analyses. Kolmogorov\u2013Smirnov test and histograms were used to determine whether there was a normal distribution. The non-parametric data of the groups were compared using the Mann\u2013Whitney U test and the parametric data using the \u0131ndependent\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      test. Chi-square test was used to test categorical data. Cases with\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05 were considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      While 22 (6.2%) patients had renal insufficiency, 332 (95.8%) patients did not have renal insufficiency. In the evaluation made in terms of AP severity; according to Balthazar classification at admission, there was no difference in mild and moderate pancreatitis for kidney insufficiency in both groups, but it was significantly higher in the group with severe pancreatitis [2 (9.1%) versus 1 (0.3%),\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001]. In the evaluation made after 72 hours; renal failure was significantly lower in the group with mild pancreatitis [11 (50.0%) versus 245 (73.8%),\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      : 0.016] and severe renal failure was significantly higher in severe pancreatitis [7 (31.8%) versus 13 (%) 3.9),\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Early intensive care unit admission and close follow-up and early treatment in AP patients change the course of the disease. In our study, we showed that serum creatinine level is an important parameter in the course of AP and has a predictive value for the course of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_728_22","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T06:00:56Z","timestamp":1689314456000},"page":"680-685","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Course of Acute Pancreatitis Patients with Renal Failure According to Balthazar Classification"],"prefix":"10.4103","volume":"26","author":[{"given":"G","family":"Kilic","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Van Education and Research Hospital, Division of Gastroenterology, Van, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GE","family":"Kilic","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Van 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