{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:35Z","timestamp":1787762075943,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Essential oils (EOs) have a considerable amount of therapeutic and preventive effect in treating dental diseases due to their wider potential as antibacterial and anti-inflammatory agents. EOs like virgin coconut oil, eucalyptus oil, peppermint oil thyme oil, and clove oil, when used in combination, may further have enhanced antimicrobial effects. However, limited information exists on the synergistic effect of these oils when used in combination, especially on the primary periodontal pathogen\n                      <jats:italic toggle=\"yes\">Porphyromonas<\/jats:italic>\n                      <jats:italic toggle=\"yes\">gingivalis<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      The current study aims to compare the antimicrobial efficacy of commercially available EO on the periodontal pathogen,\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      , in comparison to chlorhexidine (CHX).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Antimicrobial efficacy of EO and CHX was assessed at various concentrations against the periodontal pathogen\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      , by evaluating the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      was seen to be sensitive at a MIC of 100 \u00b5g\/ml and 50 \u00b5g\/ml concentration of the EO, which is regarded as the MIC of EO against\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      and CHX effectively inhibited microbial growth at 0.4 \u00b5g\/ml.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      A combination of EOs possesses a potent antibacterial activity against\n                      <jats:italic toggle=\"yes\">P. gingivalis<\/jats:italic>\n                      , and the antibacterial efficacy increases with increasing concentration of EOs.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_787_22","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T22:58:29Z","timestamp":1687561109000},"page":"625-629","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Antimicrobial Efficacy of Blended Essential Oil and Chlorhexidine against Periodontal Pathogen (P.gingivalis)\u2013An In Vitro Study"],"prefix":"10.4103","volume":"26","author":[{"given":"G","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Periodontology, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur 603203, Kancheepuram, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MP","family":"Rajula","sequence":"additional","affiliation":[{"name":"Department of Periodontology, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur 603203, Kancheepuram, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KS","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Periodontology, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur 603203, Kancheepuram, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PL","family":"Ravishankar","sequence":"additional","affiliation":[{"name":"Department of Periodontology, SRM Kattankulathur Dental College and Hospital, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur 603203, Kancheepuram, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DH","family":"Albar","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, College of Dentistry, Jazan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MA","family":"Bahammam","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Faculty of Dentistry, King Abdulaziz University. 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