{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:54Z","timestamp":1787762094024,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Splenomegaly is one of the complications of sickle cell disease (SCD) occurring in early childhood. This risk is reduced by the age of five years as the spleen undergoes auto splenectomy as a consequence of recurrent vasooclusion and splenic infarction. However, in some variants of SCD, the persistence of the spleen occurs. This can be complicated rarely by the formation of a splenic pseudocyst. We report a 17-year-old teenager with sickle cell anemia who presented with an 8-year history of gradually increasing left-sided abdominal swelling and a 2-month history of recurrent left upper abdominal pain. A computerized tomography scan revealed splenomegaly and multiple splenic cysts, not responsive to opioid analgesics which necessitated a total splenectomy. The histology report found an absence of epithelial lining confirming splenic pseudocysts. SCD patients with splenomegaly have underlying splenic infarction, which is a predisposition to splenic pseudocyst formation, though a rare occurrence. Many patients with splenic pseudocyst are usually asymptomatic and do not need intervention. However, the index patient developed serious symptoms indicating a need for a total splenectomy. A splenic pseudocyst is rare and found in &lt;1% of splenectomies.<\/jats:p>","DOI":"10.4103\/njcp.njcp_793_22","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T06:02:09Z","timestamp":1689314529000},"page":"844-846","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Splenomegaly and Splenic Pseudocyst in a Female Teenage Patient with Sickle Cell Anemia\u2013A Case Report"],"prefix":"10.4103","volume":"26","author":[{"given":"AK","family":"Orolu","sequence":"first","affiliation":[{"name":"Department of Heamatology, Alimosho General Hospital, Igando, Lagos State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SF","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of General Surgery, Alimosho General Hospital, Igando, Lagos State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OT","family":"Oluwaseun","sequence":"additional","affiliation":[{"name":"Department of Heamatology, Alimosho General Hospital, Igando, Lagos State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"R1-20240907","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2141.2011.08999.x","article-title":"Acute splenic sequestration crisis in sickle cell disease:Cohort study of 190 paediatric patients","volume":"156","author":"Brousse","year":"2012","journal-title":"Br J Haematol"},{"key":"R2-20240907","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3109\/03630269.2015.1072550","article-title":"Acute splenic sequestration srisis in adult sickle cell disease:A report of 16 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in Saudi patients with sickle cell disease","volume":"18","author":"Al-Salem","year":"1998","journal-title":"Ann Saudi Med"},{"key":"R7-20240907","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2141.2011.08999.x","article-title":"Acute splenic sequestration crisis in sickle cell disease:Cohort study of 190 paediatric patients","volume":"156","author":"Brousse","year":"2012","journal-title":"Br J Haematol"},{"key":"R9-20240907","doi-asserted-by":"crossref","first-page":"18","DOI":"10.4103\/0971-9261.74516","article-title":"Epithelial cyst of the spleen","volume":"16","author":"Daga","year":"2011","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R10-20240907","first-page":"209","article-title":"Nonparasitic benign cystic tumors of the spleen","volume":"96","author":"Fowler","year":"1953","journal-title":"Int Abstr Surg"},{"key":"R12-20240907","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/B978-0-323-40232-3.00142-4","article-title":"Cysts and tumors of the spleen","author":"Pointer","year":"2019","journal-title":"Shackelford's Surgery of the Alimentary Tract, 2 Volume Set"},{"key":"R13-20240907","first-page":"14","article-title":"Large primary splenic cyst: A laparoscopic technique","volume":"5","author":"Geraghty","journal-title":"J Minim Access Surg"}],"container-title":["Nigerian Journal of Clinical 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