{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:33:15Z","timestamp":1787761995598,"version":"build-2784847793"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Kidney biopsy remains the best standard for kidney tissue analysis. Although percutaneous kidney biopsy is an invasive procedure, it is an indispensable part of interventional nephrology for accurate diagnosis, selection of appropriate therapy protocol, and prognostication of kidney diseases in children. With improvement in expertise among pediatric nephrologists, data on procedure outcomes are now being documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>We aimed to describe the outcomes in a 5-year practice of kidney biopsy at the pediatric nephrology unit in a southeast Nigerian tertiary hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>An observational descriptive study conducted on the kidney biopsy performed in our facility from 2017 to 2022. The focus was on the patients\u2019 clinical profile, indications for biopsy, the adopted procedure, and the histopathologic findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 69 patients had kidney biopsy, 40 (58.0%) were males, while 29 (42.0%) were females. Sixty-four (92.7%) patients had the procedure at the age of &gt;10 years, while five (7.2%) at the age of &lt;7 years. The patients\u2019 prebiopsy mean systolic and diastolic blood pressures were 111.20 \u00b1 16.93 and 74.64 \u00b1 12.69 mmHg, respectively. Their estimated glomerular filtration rate (eGFR) was 119.27 \u00b1 52.78 ml\/min\/1.73 m\n                      <jats:sup>2<\/jats:sup>\n                      . The most frequent indication was steroid resistance (39\/69, 56.5%). Focal segmental glomerulosclerosis was the commonest histopathologic finding (38\/69, 55.0%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Outcomes of percutaneous kidney biopsy at a Nigerian tertiary hospital are adjudged successful. The histopathologic patterns highlight FSGS as the major cause of steroid resistance in childhood nephrotic syndrome in this clime.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_855_22","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T06:01:28Z","timestamp":1689314488000},"page":"795-801","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Percutaneous Kidney Biopsy and the Histopathologic Patterns of Kidney Diseases in Children: An Observational Descriptive Study at a South-East Nigerian Tertiary Hospital"],"prefix":"10.4103","volume":"26","author":[{"given":"NR","family":"Mbanefo","sequence":"first","affiliation":[{"name":"Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, 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