{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:32:52Z","timestamp":1786649572623,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"\n Background:<\/jats:title>\n Hypertension is a major non-communicable disease of public health concern. In Nigeria, the rate is between 28% and 42.2%. Hypertension or the prolonged use of some antihypertensive drugs has been associated with hearing loss in studies. There is a paucity of studies on this in our environment.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n Therefore, this study aims to evaluate the relationship between hearing thresholds and hypertension.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This was a hospital-based cross-sectional comparative study of hypertensive and non-hypertensive patients. Ethical approval for the study was obtained. Informed consent was obtained from the participants. A researcher-administered structured pro forma was utilised to obtain demographic and medical history data. Blood pressure measurement and pure-tone audiometry were performed on all the participants. Data were analysed using SPSS version 25.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n One hundred and twenty-eight participants each were recruited from the hypertensive and control groups for the study. The age range of the hypertension group was 27\u201360 years. The frequency of hearing loss amongst the hypertension and control groups was 47.7% and 15.6%, respectively (\n P<\/jats:italic>\n < 0.001). The mean pure-tone average for the hypertension group was 29.2 dB \u00b1 18.5\/28.3 dB \u00b1 20.5 and 21.6 dB \u00b1 8.7\/20.6 dB \u00b1 8 in the right and left ears of the hypertensive and control groups, respectively. The frequency of hearing loss in the controlled and uncontrolled hypertensive subjects was 44.7% and 52%, respectively (\n P<\/jats:italic>\n = 0.424). Hearing loss frequency was 50% in hypertensive subjects on diuretic and\/or beta-blockers and 46% in those on other antihypertensive drugs (\n P<\/jats:italic>\n = 0.650).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The frequency of hearing loss in the hypertension group was significantly higher than in the control group.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/npmj.npmj_136_25","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:00:06Z","timestamp":1767337206000},"page":"134-139","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Relation between Hypertension and Hearing Loss: A Study of Hypertensive Patients in a Tertiary Hospital in Lagos, Nigeria"],"prefix":"10.4103","volume":"33","author":[{"given":"Chinyere Nkiruka","family":"Asoegwu","sequence":"first","affiliation":[{"name":"Department of Surgery, College of Medicine, University of Lagos, Lagos, Nigeria"},{"name":"Department of Ear, Nose, and Throat Surgery, Lagos University Teaching Hospital, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nkiruka Augusta","family":"Wakwe","sequence":"additional","affiliation":[{"name":"Department of Ear, Nose, and Throat Surgery, Lagos University Teaching Hospital, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet Ngozi","family":"Ajuluchukwu","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement Chukwuemeka","family":"Nwawolo","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine, University of Lagos, Lagos, Nigeria"},{"name":"Department of Ear, Nose, and Throat Surgery, Lagos University Teaching Hospital, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"R1-20260420","doi-asserted-by":"crossref","first-page":"262","DOI":"10.5830\/CVJA-2017-040","article-title":"Roadmap to achieve 25% hypertension control in Africa by 2025","volume":"28","author":"Dzudie","year":"2017","journal-title":"Cardiovasc J Afr"},{"key":"R4-20260420","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/HJH.0000000000000413","article-title":"An estimate of the prevalence of hypertension in Nigeria: A systematic review and meta-analysis","volume":"33","author":"Adeloye","year":"2015","journal-title":"J Hypertens"},{"key":"R5-20260420","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3389\/fneur.2016.00171","article-title":"Positive association between tinnitus and arterial hypertension","volume":"7","author":"Figueiredo","year":"2016","journal-title":"Front Neurol"},{"key":"R6-20260420","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0378-5955(82)90064-8","article-title":"Cochlear transduction: An integrative model and review","volume":"6","author":"Brownell","year":"1982","journal-title":"Hear Res"},{"key":"R7-20260420","first-page":"63","article-title":"Relation between arterial hypertension and hearing loss","volume":"13","author":"Mondelli","year":"2009","journal-title":"Int Arch Otolaringol"},{"key":"R8-20260420","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.heares.2011.08.006","article-title":"Physiopathology of the cochlear microcirculation","volume":"282","author":"Shi","year":"2011","journal-title":"Hear Res"},{"key":"R9-20260420","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1111\/j.1532-5415.2011.03444.x","article-title":"Hearing sensitivity in older adults: Associations with cardiovascular risk factors in the health, aging and body composition study","volume":"59","author":"Helzner","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"R10-20260420","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.amjmed.2015.11.014","article-title":"Hypertension, diuretics, and hearing loss","volume":"129","author":"Lin","year":"2016","journal-title":"Am J Med"},{"key":"R11-20260420","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.joto.2016.10.001","article-title":"Ototoxic effects and mechanisms of loop diuretics","volume":"11","author":"Ding","year":"2016","journal-title":"J Otol"},{"key":"R12-20260420","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1080\/14992027.2017.1405162","article-title":"Use of beta blockers is associated with hearing loss","volume":"57","author":"Al-Ghamdi","year":"2018","journal-title":"Int J Audiol"},{"key":"R15-20260420","doi-asserted-by":"crossref","first-page":"74","DOI":"10.5395\/rde.2016.41.1.74","article-title":"Statistical notes for clinical researchers: Sample size calculation 1. 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