{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:30:05Z","timestamp":1787841005249,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Malaria remains the deadliest parasitic disease and continues to cause more than half a million deaths across the world each year, mainly victims are sub-Saharan children. Malaria is a common reason for paediatric hospitalisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective was to characterise malaria and describe the evolution after treatment in the paediatric department of the University Hospital Centre Amissa Bongo de Franceville.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a cross-sectional study conducted from 1 February 2023 to 15 May 2023. A clinical and biological diagnosis was made in febrile children aged from 6 months to 15 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 306 patients were included. The mean age was 50.4 \u00b1 44.3 months, 94.3% had consulted within \u226548 h and self-medication was practiced by 83.3%. The prevalence of malaria was 17.3%. Fever \u02c339\u00b08C (adjusted odds ratios [aOR] = 2.68; 95% confidence interval [CI] = [1.32\u20135.48];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01), chills (aOR = 2.14; 95% CI = [1.13\u20134.11];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01) and nausea\u2013vomiting (aOR = 2.03; 95% CI = [1.06\u20133.83];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03) were the factors associated with the occurrence of malaria. The majority of children were treated for simple malaria with artemisinin-based combination therapy. A total of 16\/53 was seen in post-therapeutic consultation. Of them, 2 patients had a positive thick drop.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Non-compliance with preventive measures and the misuse of antimalarials further complicate the clinical picture, requiring parenteral management for the most part.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/npmj.npmj_200_24","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T04:00:22Z","timestamp":1733284822000},"page":"318-324","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiological, Clinical and Paraclinical Profile of Paediatric Malaria at University Hospital Centre Amissa Bongo in Franceville, Gabon"],"prefix":"10.4103","volume":"31","author":[{"given":"Rom\u00e9o Karl","family":"Imboumy-Limoukou","sequence":"first","affiliation":[{"name":"Unit of Evolution, Epidemiology and Parasitic Resistances (UNEEREP), Franceville International Medical Research Center (CIRMF), Franceville, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Claude","family":"Biteghe-Bi-Essone","sequence":"additional","affiliation":[{"name":"Unit of Evolution, Epidemiology and Parasitic Resistances (UNEEREP), Franceville International Medical Research Center (CIRMF), Franceville, Gabon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine Lydie","family":"Oyegue-Liabagui","sequence":"additional","affiliation":[{"name":"Unit of Evolution, Epidemiology and Parasitic Resistances (UNEEREP), Franceville International Medical Research Center (CIRMF), Franceville, Gabon"},{"name":"Masuku University of Science and Technology, Molecular and Cell Biology Laboratory (LABMC), Franceville, 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