{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:19:36Z","timestamp":1787840376337,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"\n Background:<\/jats:title>\n \n Accurate detection of\n Helicobacter pylori<\/jats:italic>\n infection is crucial for properly treating patients with dyspepsia. Several invasive and non-invasive diagnostic methods are being utilised.\n <\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n \n This study aimed to determine the prevalence of\n H. pylori<\/jats:italic>\n in adult patients with dyspeptic conditions and how it related to endoscopic findings, histological features and the relationship to urea breath test (UBT) results.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n From 723, 100 adult dyspeptic outpatients who underwent UBT and endoscopy were investigated at the Department of Gastroenterology in Imam Al-Hujjah Hospital for gastroduodenal biopsy. A histopathological study was also used to identify\n H. pylori<\/jats:italic>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The study included 68 females (37\n H. pylori<\/jats:italic>\n positive and 31 with\n H. pylori<\/jats:italic>\n negative) and 32 males (13 with\n H. pylori<\/jats:italic>\n and 19 without\n H. pylori<\/jats:italic>\n ) with a female-to-male ratio of 2.1:1. The most common endoscopic finding was nodularity in 28 patients (46%)\n H. pylori<\/jats:italic>\n positive and 5 (10%)\n H. pylori<\/jats:italic>\n negative, followed by gastritis, erosive gastritis, erythema, hiatus hernia and gastric ulcer. The most common histological feature was chronic gastritis in 52 cases (64%) in the positive bacterial cases and 20 (36%) in the negative group, with a statistically significant relationship. There was a significant difference between histopathological findings with both endoscopic examination and UBT results for\n H. pylori<\/jats:italic>\n positive and negative patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n \n Endoscopic and histological studies with UBT showed a significant ability to detect\n H. pylori<\/jats:italic>\n . Early detection and treatment are crucial for the\n H. pylori<\/jats:italic>\n infection to avoid major complications.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/npmj.npmj_237_25","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:00:57Z","timestamp":1761544857000},"page":"339-344","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Monitoring of Helicobacter pylori Infection in Dyspeptic Adults Based on Histopathological, Endoscopic and Urea Breath Tests in Karbala City"],"prefix":"10.4103","volume":"32","author":[{"given":"Fatin Hasim","family":"Al-Mosawi","sequence":"first","affiliation":[{"name":"Department of Pathology and Forensic Medicine, College of Medicine, University of Kerbala, Karbala, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab A.","family":"Al-Ali","sequence":"additional","affiliation":[{"name":"Department of Pathology and 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