{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T12:27:54Z","timestamp":1786969674420,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pineoblastoma (PB) is a rare malignant embryonal tumour arising from the pineal gland. It commonly affects the paediatric age group with a slight male predilection. The typical clinical features include symptoms and signs of raised intracranial pressure, but extracranial metastasis may be seen in poorly differentiated tumours. We present a 5-year-old male who presented with clinical features suggestive of raised intracranial pressure. Radiological investigations revealed a pineal region tumour, and histopathological evaluation confirmed the diagnosis of a PB. The patient was optimised, and he had a right occipital craniotomy and microscopic surgery decompression via interhemispheric transplenial with ventriculoperitoneal shunt inserted. Fever, as a post-operative complication, was noted which necessitated removal of the shunt. The patient did well and was followed up bi-weekly. Unfortunately, the patient presented 5 months later with a recurrence, and he succumbed to his illness.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Highlights (Key Messages<\/jats:bold>\n                    )\n                  <\/jats:p>\n                  <jats:p>\u2022 Pineoblastoma is a high-grade aggressive embryonal tumour arising from the pineal gland<\/jats:p>\n                  <jats:p>\u2022 It typically affects the paediatric population with a slight male preponderance<\/jats:p>\n                  <jats:p>\u2022 Prognosis is poor with high rates of mortality<\/jats:p>\n                  <jats:p>\u2022 Imaging studies are necessary but prompt histopathological evaluation is required for a definitive diagnosis of this tumour<\/jats:p>","DOI":"10.4103\/npmj.npmj_635_25","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T04:00:27Z","timestamp":1786939227000},"page":"683-686","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pineoblastoma in a 5-Year-Old Male: A Case Report and Review of Literature"],"prefix":"10.4103","volume":"33","author":[{"given":"Zainab Ali","family":"Adamu","sequence":"first","affiliation":[{"name":"Department of Pathology and Radiology, Ahmadu Bello University Teaching Hospital (ABUTH), P.M.B.06, Shika-Zaria, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garba Dahiru","family":"Waziri","sequence":"additional","affiliation":[{"name":"Department of Pathology and Radiology, Ahmadu Bello University Teaching Hospital (ABUTH), P.M.B.06, Shika-Zaria, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrazaq Ajanaku","family":"Jimoh","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology and Forensic Medicine, Federal University of Health Sciences, Azare, Bauchi, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullahi","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Pathology and Radiology, Ahmadu Bello University Teaching Hospital (ABUTH), P.M.B.06, Shika-Zaria, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Harrison","family":"Lawan","sequence":"additional","affiliation":[{"name":"Department of Pathology and Radiology, Ahmadu Bello University Teaching Hospital (ABUTH), P.M.B.06, Shika-Zaria, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel Jonathan","family":"Lolo","sequence":"additional","affiliation":[{"name":"Department of Pathology and Radiology, Ahmadu Bello University Teaching Hospital (ABUTH), P.M.B.06, Shika-Zaria, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"R1-20260817","first-page":"vdac056","article-title":"Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data","volume":"4","author":"Hansford","year":"2022","journal-title":"Neurooncol Adv"},{"key":"R2-20260817","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 World Health Organization classification of tumors of the central nervous system: A summary","volume":"131","author":"Louis","year":"2016","journal-title":"Acta Neuropathol"},{"key":"R3-20260817","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/cncr.26300","article-title":"The long-term postsurgical prognosis of patients with 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institute experience in Taiwan","volume":"2","author":"Kang","year":"2018","journal-title":"Ther Radiol Oncol"},{"key":"R12-20260817","doi-asserted-by":"crossref","first-page":"100477","DOI":"10.1016\/j.inat.2019.100477","article-title":"Pineoblastomas: A long term follow study of three cases in Helsinki neurosurgery","volume":"18","author":"Choque-Velasquez","year":"2019","journal-title":"Interdiscip Neurosurg"},{"key":"R13-20260817","first-page":"e5852","article-title":"Pineoblastoma in adults: A rare case successfully treated with multimodal approach including craniospinal irradiation using helical tomotherapy","volume":"11","author":"Gaito","year":"2019","journal-title":"Cureus"}],"container-title":["Nigerian Postgraduate Medical 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