{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:29:46Z","timestamp":1786739386547,"version":"build-2736575974"},"reference-count":80,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0 http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.4103\/nrr.nrr-d-25-00295","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T05:00:12Z","timestamp":1770008412000},"page":"5052-5062","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["The m6A writer VIRMA regulates the developmental elimination of retinal astrocytes and retinal vascular integrity maintenance"],"prefix":"10.4103","volume":"21","author":[{"given":"Cuiting","family":"Wu","sequence":"first","affiliation":[{"name":"Shenzhen Neher Neural Plasticity Laboratory, Shenzhen Key Laboratory of Drug Addiction, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong Province, China"},{"name":"University of Chinese Academy of Sciences, Beijing, China"},{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Wu","sequence":"additional","affiliation":[{"name":"Shenzhen Neher Neural Plasticity Laboratory, Shenzhen Key Laboratory of Drug Addiction, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong Province, China"},{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[{"name":"Shenzhen Neher Neural Plasticity Laboratory, Shenzhen Key Laboratory of Drug Addiction, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong Province, China"},{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"},{"name":"Faculty of Life and Health Sciences, Shenzhen University of Advanced Technology, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xidan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shenzhen Neher Neural Plasticity Laboratory, Shenzhen Key Laboratory of Drug Addiction, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong Province, China"},{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tu","sequence":"additional","affiliation":[{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Shen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Reproductive Medicine and Offspring Health, Women\u2019s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Gusu School, Nanjing Medical University, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2184-3023","authenticated-orcid":false,"given":"Tao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shenzhen Neher Neural Plasticity Laboratory, Shenzhen Key Laboratory of Drug Addiction, the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong Province, China"},{"name":"Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, Guangdong Province, China"},{"name":"Faculty of Life and Health Sciences, Shenzhen University of Advanced Technology, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,27]]},"reference":[{"key":"R1-20260803","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tins.2010.12.001","article-title":"Astrocyte-neuron metabolic relationships: for better and for worse","volume":"34","author":"Allaman","year":"2011","journal-title":"Trends Neurosci"},{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/j.cell.2019.01.021","article-title":"VEGF in signaling and disease: beyond discovery and development","volume":"176","author":"Apte","year":"2019","journal-title":"Cell"},{"key":"R3-20260803","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41576-022-00534-0","article-title":"Biological roles of adenine methylation in RNA","volume":"24","author":"Boulias","year":"2023","journal-title":"Nat Rev Genet"},{"key":"R4-20260803","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nbt.4096","article-title":"Integrating single-cell transcriptomic data across different conditions, technologies, and species","volume":"36","author":"Butler","year":"2018","journal-title":"Nat Biotechnol"},{"key":"R5-20260803","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/glia.20733","article-title":"In vivo characterization of astrocyte precursor cells (APCs) and astrocytes in developing rat retinae: differentiation, proliferation, and apoptosis","volume":"57","author":"Chan-Ling","year":"2009","journal-title":"Glia"},{"key":"R6-20260803","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.gpb.2018.12.007","article-title":"m(6)A regulates neurogenesis and neuronal development by modulating histone methyltransferase Ezh2","volume":"17","author":"Chen","year":"2019","journal-title":"Genomics Proteomics Bioinformatics"},{"key":"R7-20260803","doi-asserted-by":"crossref","first-page":"659","DOI":"10.4161\/cbt.4.6.1733","article-title":"Recombinant semaphorin 6A-1 ectodomain inhibits in vivo growth factor and tumor cell line-induced angiogenesis","volume":"4","author":"Dhanabal","year":"2005","journal-title":"Cancer Biol Ther"},{"key":"R8-20260803","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1007\/s00125-023-05995-4","article-title":"Retinal inflammation in murine models of type 1 and type 2 diabetes with diabetic retinopathy","volume":"66","author":"Dharmarajan","year":"2023","journal-title":"Diabetologia"},{"key":"R9-20260803","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nature11112","article-title":"Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq","volume":"485","author":"Dominissini","year":"2012","journal-title":"Nature"},{"key":"R10-20260803","first-page":"3500","article-title":"Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion","volume":"43","author":"Dorrell","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R11-20260803","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/glia.20900","article-title":"Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy","volume":"58","author":"Dorrell","year":"2010","journal-title":"Glia"},{"key":"R12-20260803","doi-asserted-by":"crossref","first-page":"82","DOI":"10.4161\/cam.22480","article-title":"Laminins and retinal vascular development","volume":"7","author":"Edwards","year":"2013","journal-title":"Cell Adh Migr"},{"key":"R13-20260803","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/nrg3724","article-title":"Gene expression regulation mediated through reversible m\u2076A RNA methylation","volume":"15","author":"Fu","year":"2014","journal-title":"Nat Rev Genet"},{"key":"R14-20260803","doi-asserted-by":"crossref","first-page":"5675","DOI":"10.1038\/s41467-021-25968-8","article-title":"Multi-species single-cell transcriptomic analysis of ocular compartment regulons","volume":"12","author":"Gautam","year":"2021","journal-title":"Nat Commun"},{"key":"R15-20260803","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/eye.2014.70","article-title":"Familial exudative vitreoretinopathy and related retinopathies","volume":"29","author":"Gilmour","year":"2015","journal-title":"Eye (Lond)"},{"key":"R16-20260803","doi-asserted-by":"crossref","first-page":"dev201047","DOI":"10.1242\/dev.201047","article-title":"Microglia refine developing retinal astrocytic and vascular networks through the complement C3\/C3aR axis","volume":"150","author":"Gnanaguru","year":"2023","journal-title":"Development"},{"key":"R17-20260803","doi-asserted-by":"crossref","first-page":"705783","DOI":"10.1155\/2014\/705783","article-title":"The role of microglia in diabetic retinopathy","volume":"2014","author":"Grigsby","year":"2014","journal-title":"J Ophthalmol"},{"key":"R18-20260803","article-title":"N6-methyladenosine METTL3-induced circMYO1C accelerates the pancreatic ductal adenocarcinoma tumorigenesis through IGF2BP2\/VEGFA manner","author":"Guan","year":"2022","journal-title":"Research Square [Preprint]"},{"key":"R19-20260803","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1038\/s41467-018-06327-6","article-title":"Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype","volume":"9","author":"Hosoi","year":"2018","journal-title":"Nat Commun"},{"key":"R20-20260803","doi-asserted-by":"crossref","first-page":"103969","DOI":"10.1016\/j.mvr.2019.103969","article-title":"Use of optical coherence tomography angiography for assessment of microvascular changes in the macula and optic nerve head in hypertensive patients without hypertensive retinopathy","volume":"129","author":"Hua","year":"2020","journal-title":"Microvasc Res"},{"key":"R21-20260803","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/s41392-020-00450-x","article-title":"The role of m6A modification in the biological functions and diseases","volume":"6","author":"Jiang","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"R22-20260803","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/s41467-021-21246-9","article-title":"Inference and analysis of cell-cell communication using CellChat","volume":"12","author":"Jin","year":"2021","journal-title":"Nat Commun"},{"key":"R23-20260803","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.imbio.2010.05.010","article-title":"Microglia in the healthy and degenerating retina: insights from novel mouse models","volume":"215","author":"Karlstetter","year":"2010","journal-title":"Immunobiology"},{"key":"R24-20260803","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/glia.23269","article-title":"Sox2 regulates astrocytic and vascular development in the retina","volume":"66","author":"Kautzman","year":"2018","journal-title":"Glia"},{"key":"R26-20260803","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1101\/gad.309146.117","article-title":"Zc3h13\/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15\/Spenito to the m(6)A machinery component Wtap\/Fl(2)d","volume":"32","author":"Knuckles","year":"2018","journal-title":"Genes Dev"},{"key":"R27-20260803","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.devcel.2015.06.004","article-title":"Mechanisms of vessel pruning and regression","volume":"34","author":"Korn","year":"2015","journal-title":"Dev Cell"},{"key":"R28-20260803","doi-asserted-by":"crossref","first-page":"918","DOI":"10.4103\/2230-8210.102992","article-title":"Aberrant angiogenesis: The gateway to diabetic complications","volume":"16","author":"Kota","year":"2012","journal-title":"Indian J Endocrinol Metab"},{"key":"R29-20260803","doi-asserted-by":"crossref","first-page":"112596","DOI":"10.1016\/j.celrep.2023.112596","article-title":"Mettl14-mediated m(6)A modification ensures the cell-cycle progression of late-born retinal progenitor cells","volume":"42","author":"Li","year":"2023","journal-title":"Cell Rep"},{"key":"R30-20260803","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.4103\/NRR.NRR-D-23-01872","article-title":"The complex roles of m 6 A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases","volume":"20","author":"Li","year":"2025","journal-title":"Neural Regen Res"},{"key":"R31-20260803","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ajo.2018.11.016","article-title":"Changes in ganglion cell-inner plexiform layer thickness and retinal microvasculature in hypertension: an optical coherence tomography angiography study","volume":"199","author":"Lim","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"R32-20260803","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41419-022-04950-2","article-title":"m6A methylated EphA2 and VEGFA through IGF2BP2\/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K\/AKT and ERK1\/2 signaling","volume":"13","author":"Liu","year":"2022","journal-title":"Cell Death Dis"},{"key":"R33-20260803","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1038\/s41380-024-02574-w","article-title":"Integration of multi-omics summary data reveals the role of N6-methyladenosine in neuropsychiatric disorders","volume":"29","author":"Liufu","year":"2024","journal-title":"Mol Psychiatry"},{"key":"R34-20260803","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41583-019-0244-z","article-title":"The m(6)A epitranscriptome: transcriptome plasticity in brain development and function","volume":"21","author":"Livneh","year":"2020","journal-title":"Nat Rev Neurosci"},{"key":"R35-20260803","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s13059-018-1435-z","article-title":"RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum","volume":"19","author":"Ma","year":"2018","journal-title":"Genome Biol"},{"key":"R36-20260803","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.cell.2015.05.002","article-title":"Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets","volume":"161","author":"Macosko","year":"2015","journal-title":"Cell"},{"key":"R37-20260803","doi-asserted-by":"crossref","first-page":"6823","DOI":"10.1167\/iovs.15-17527","article-title":"Strain-dependent anterior segment dysgenesis and progression to glaucoma in Col4a1 mutant mice","volume":"56","author":"Mao","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R38-20260803","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.neuroscience.2019.05.021","article-title":"Eye drop instillation of the Rac1 modulator CNF1 attenuates retinal gliosis and ameliorates visual performance in a rat model of hypertensive retinopathy","volume":"411","author":"Matteucci","year":"2019","journal-title":"Neuroscience"},{"key":"R39-20260803","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1038\/s41467-024-45456-z","article-title":"Modeling early pathophysiological phenotypes of diabetic retinopathy in a human inner blood-retinal barrier-on-a-chip","volume":"15","author":"Maurissen","year":"2024","journal-title":"Nat Commun"},{"key":"R40-20260803","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.molcel.2022.12.019","article-title":"RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia","volume":"83","author":"McMillan","year":"2023","journal-title":"Mol Cell"},{"key":"R41-20260803","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.3390\/cells10071703","article-title":"Integrins: an important link between angiogenesis, inflammation and eye diseases","volume":"10","author":"Mrugacz","year":"2021","journal-title":"Cells"},{"key":"R42-20260803","doi-asserted-by":"crossref","first-page":"e75827","DOI":"10.7554\/eLife.75827","article-title":"The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells","volume":"11","author":"Niu","year":"2022","journal-title":"Elife"},{"key":"R43-20260803","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1002\/glia.23189","article-title":"Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development","volume":"65","author":"O\u2019Sullivan","year":"2017","journal-title":"Glia"},{"key":"R44-20260803","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.ydbio.2021.07.007","article-title":"Seeing stars: Development and function of retinal astrocytes","volume":"478","author":"Paisley","year":"2021","journal-title":"Dev Biol"},{"key":"R45-20260803","doi-asserted-by":"crossref","first-page":"e3000492","DOI":"10.1371\/journal.pbio.3000492","article-title":"Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia","volume":"17","author":"Pu\u00f1al","year":"2019","journal-title":"PLoS Biol"},{"key":"R46-20260803","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1172\/JCI126655","article-title":"Roles of HIFs and VEGF in angiogenesis in the retina and brain","volume":"129","author":"Rattner","year":"2019","journal-title":"J Clin Invest"},{"key":"R47-20260803","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0166-2236(97)01139-9","article-title":"Reactive astrocytes: cellular and molecular cues to biological function","volume":"20","author":"Ridet","year":"1997","journal-title":"Trends Neurosci"},{"key":"R48-20260803","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.expneurol.2018.05.005","article-title":"Neurosteroid allopregnanolone reduces ipsilateral visual cortex potentiation following unilateral optic nerve injury","volume":"306","author":"Sergeeva","year":"2018","journal-title":"Exp Neurol"},{"key":"R49-20260803","doi-asserted-by":"crossref","first-page":"108107","DOI":"10.1016\/j.exer.2020.108107","article-title":"FTO regulates ocular angiogenesis via m(6)A-YTHDF2-dependent mechanism","volume":"197","author":"Shan","year":"2020","journal-title":"Exp Eye Res"},{"key":"R50-20260803","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/s41586-018-0666-1","article-title":"m(6)A facilitates hippocampus-dependent learning and memory through YTHDF1","volume":"563","author":"Shi","year":"2018","journal-title":"Nature"},{"key":"R51-20260803","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.molcel.2019.04.025","article-title":"Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers","volume":"74","author":"Shi","year":"2019","journal-title":"Mol Cell"},{"key":"R52-20260803","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/s41591-020-0844-1","article-title":"A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors","volume":"26","author":"Slyper","year":"2020","journal-title":"Nat Med"},{"key":"R53-20260803","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.cell.2007.10.036","article-title":"The classical complement cascade mediates CNS synapse elimination","volume":"131","author":"Stevens","year":"2007","journal-title":"Cell"},{"key":"R54-20260803","doi-asserted-by":"crossref","first-page":"4738","DOI":"10.1523\/JNEUROSCI.15-07-04738.1995","article-title":"Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia","volume":"15","author":"Stone","year":"1995","journal-title":"J Neurosci"},{"key":"R55-20260803","doi-asserted-by":"crossref","first-page":"3975","DOI":"10.3390\/jcm13133975","article-title":"Assessment of blood flow velocity in retinal vasculitis using the retinal function imager-A pilot study","volume":"13","author":"Stuebiger","year":"2024","journal-title":"J Clin Med"},{"key":"R56-20260803","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1038\/s41422-022-00725-8","article-title":"Cryo-EM structures of human m6A writer complexes","volume":"32","author":"Su","year":"2022","journal-title":"Cell Res"},{"key":"R57-20260803","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1084\/jem.20160412","article-title":"Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries","volume":"214","author":"Sun","year":"2017","journal-title":"J Exp Med"},{"key":"R58-20260803","doi-asserted-by":"crossref","first-page":"108718","DOI":"10.1016\/j.exer.2021.108718","article-title":"Single cell RNA sequencing (scRNA-Seq) deciphering pathological alterations in streptozotocin-induced diabetic retinas","volume":"210","author":"Sun","year":"2021","journal-title":"Exp Eye Res"},{"key":"R59-20260803","doi-asserted-by":"crossref","first-page":"277","DOI":"10.7150\/thno.63441","article-title":"METTL3-mediated N(6)-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication","volume":"12","author":"Suo","year":"2022","journal-title":"Theranostics"},{"key":"R60-20260803","doi-asserted-by":"crossref","first-page":"108189","DOI":"10.1016\/j.celrep.2020.108189","article-title":"Single-nucleus RNA-Seq is not suitable for detection of microglial activation genes in humans","volume":"32","author":"Thrupp","year":"2020","journal-title":"Cell Rep"},{"key":"R61-20260803","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.06.003","article-title":"Glia-neuron interactions in the mammalian retina","volume":"51","author":"Vecino","year":"2016","journal-title":"Prog Retin Eye Res"},{"key":"R62-20260803","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/nrn1722","article-title":"Astrocytes, from brain glue to communication elements: the revolution continues","volume":"6","author":"Volterra","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"R63-20260803","doi-asserted-by":"crossref","first-page":"611660","DOI":"10.3389\/fonc.2021.611660","article-title":"m(6)A modifications play crucial roles in glial cell development and brain tumorigenesis","volume":"11","author":"Wang","year":"2021","journal-title":"Front Oncol"},{"key":"R64-20260803","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/s41392-022-01277-4","article-title":"Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"R65-20260803","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s40035-023-00386-6","article-title":"N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer\u2019s disease","volume":"12","author":"Wang","year":"2023","journal-title":"Transl Neurodegener"},{"key":"R66-20260803","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2012.10.042","article-title":"Norrin\/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity","volume":"151","author":"Wang","year":"2012","journal-title":"Cell"},{"key":"R67-20260803","doi-asserted-by":"crossref","first-page":"E6927","DOI":"10.1073\/pnas.1512683112","article-title":"Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A","volume":"112","author":"Wei","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R68-20260803","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/cac2.12579","article-title":"\u201cFind Me\u201d and \u201cEat Me\u201d signals: tools to drive phagocytic processes for modulating antitumor immunity","volume":"44","author":"Xiao","year":"2024","journal-title":"Cancer Commun (Lond)"},{"key":"R69-20260803","doi-asserted-by":"crossref","first-page":"e79994","DOI":"10.7554\/eLife.79994","article-title":"m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina","volume":"11","author":"Xin","year":"2022","journal-title":"Elife"},{"key":"R70-20260803","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/s41419-021-04390-4","article-title":"Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma","volume":"12","author":"Yang","year":"2021","journal-title":"Cell Death Dis"},{"key":"R71-20260803","doi-asserted-by":"crossref","first-page":"e158428","DOI":"10.1172\/jci.insight.158428","article-title":"CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt\/cadherin axis","volume":"7","author":"Yang","year":"2022","journal-title":"JCI Insight"},{"key":"R72-20260803","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12915-022-01335-x","article-title":"Mettl14-mediated m6A modification is essential for visual function and retinal photoreceptor survival","volume":"20","author":"Yang","year":"2022","journal-title":"BMC Biol"},{"key":"R73-20260803","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.ymthe.2020.07.022","article-title":"Role of METTL3-dependent N(6)-methyladenosine mRNA modification in the promotion of angiogenesis","volume":"28","author":"Yao","year":"2020","journal-title":"Mol Ther"},{"key":"R74-20260803","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1016\/j.cub.2013.08.015","article-title":"Rapid innate defensive responses of mice to looming visual stimuli","volume":"23","author":"Yilmaz","year":"2013","journal-title":"Curr Biol"},{"key":"R75-20260803","doi-asserted-by":"crossref","first-page":"108811","DOI":"10.1016\/j.exer.2021.108811","article-title":"Single-cell RNA-sequencing analysis of the ciliary epithelium and contiguous tissues in the mouse eye","volume":"213","author":"Youkilis","year":"2021","journal-title":"Exp Eye Res"},{"key":"R76-20260803","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41421-018-0019-0","article-title":"VIRMA mediates preferential m(6)A mRNA methylation in 3\u2019UTR and near stop codon and associates with alternative polyadenylation","volume":"4","author":"Yue","year":"2018","journal-title":"Cell Discov"},{"key":"R77-20260803","doi-asserted-by":"crossref","first-page":"e2101","DOI":"10.1038\/cddis.2015.347","article-title":"Angiopoietin 2 induces astrocyte apoptosis via \u03b1v\u03b25-integrin signaling in diabetic retinopathy","volume":"7","author":"Yun","year":"2016","journal-title":"Cell Death Dis"},{"key":"R78-20260803","doi-asserted-by":"crossref","first-page":"e2006092","DOI":"10.1371\/journal.pbio.2006092","article-title":"Refined RIP-seq protocol for epitranscriptome analysis with low input materials","volume":"16","author":"Zeng","year":"2018","journal-title":"PLoS Biol"},{"key":"R79-20260803","doi-asserted-by":"crossref","first-page":"e160517","DOI":"10.1172\/JCI160517","article-title":"FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m6A methylation of TNIP1","volume":"133","author":"Zhou","year":"2023","journal-title":"J Clin Invest"},{"key":"R80-20260803","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1186\/s12974-024-03279-1","article-title":"m6A-methylase METTL3 promotes retinal angiogenesis through modulation of metabolic reprogramming in RPE cells","volume":"21","author":"Zhou","year":"2024","journal-title":"J Neuroinflammation"},{"key":"R81-20260803","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.neuron.2019.05.027","article-title":"A VTA GABAergic neural circuit mediates visually evoked innate defensive responses","volume":"103","author":"Zhou","year":"2019","journal-title":"Neuron"}],"container-title":["Neural Regeneration Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/NRR.NRR-D-25-00295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:28:32Z","timestamp":1786735712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/NRR.NRR-D-25-00295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,27]]},"references-count":80,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/nrr.nrr-d-25-00295","relation":{},"ISSN":["1673-5374","1876-7958"],"issn-type":[{"value":"1673-5374","type":"print"},{"value":"1876-7958","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,27]]},"assertion":[{"value":"2025-03-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}