{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:29:56Z","timestamp":1787761796310,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Renal tuberculosis (TB) is a rare clinical disorder in the pediatric population. A 15-year-old female presented with intermittent blurring of vision in both eyes associated with fever, abdominal pain, and weight loss. Fundus examination showed bilateral disc edema. Her blood pressure was 220\/110 mmHg. Renal parameters were deranged with bilaterally enlarged kidneys. Renal biopsy was suggestive of epithelioid cell granuloma with Langhans type giant cells. The patient was diagnosed with as a case of refractory hypertension due to tubercular interstitial nephritis with bilateral Grade IV hypertensive retinopathy. She was started on antitubercular therapy and antihypertensives. There was a complete resolution of disc edema 2 months following initiation of therapy. Optic disc edema can be a presenting sign in renal TB. Early diagnosis and prompt referral can be associated with good visual and systemic outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_12_22","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T02:50:51Z","timestamp":1676947851000},"page":"139-141","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral disc edema"],"prefix":"10.4103","volume":"16","author":[{"given":"Biswajit","family":"Mishra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suchismita","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yamijala Neha","family":"Srija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep Kumar","family":"Panigrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-31-20240908","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/S0025-6196(12)61378-0","article-title":"Hypertension in pediatric patients: Current issues","volume":"69","author":"Morgenstern","year":"1994","journal-title":"Mayo Clin Proc"},{"key":"R2-31-20240908","doi-asserted-by":"crossref","first-page":"276","DOI":"10.12980\/apjtd.7.2017D6-402","article-title":"Hospitalized pediatric antituberculosis drug induced hepatotoxicity: Experience of an Indonesian referral hospital","volume":"7","author":"Nataprawira","year":"2017","journal-title":"Asian Pac J Trop Dis"},{"key":"R4-31-20240908","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0002-9394(14)72260-3","article-title":"The prevalence of retinal vascular abnormalities in children and adolescents with essential hypertension","volume":"111","author":"Daniels","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"R5-31-20240908","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0039-6257(01)00278-8","article-title":"Acute bilateral optic disk edema with a macular star figure in a 12-year-old girl","volume":"47","author":"Lee","year":"2002","journal-title":"Surv Ophthalmol"},{"key":"R6-31-20240908","first-page":"253","article-title":"Tuberculosis of the genitourinary system","volume":"3","author":"Merchant","year":"1993","journal-title":"Indian J Radiol Imaging"},{"key":"R7-31-20240908","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1136\/bmj.2.6184.245","article-title":"Blindness after treatment for malignant hypertension","volume":"2","author":"Cove","year":"1979","journal-title":"Br Med J"},{"key":"R8-31-20240908","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0140-6736(79)91615-5","article-title":"Blindness and paraplegia in severe childhood hypertension","volume":"2","author":"Hulse","year":"1979","journal-title":"Lancet"},{"key":"R9-31-20240908","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1136\/bjo.65.3.153","article-title":"Infarction of the optic nerve head in children with accelerated hypertension","volume":"65","author":"Taylor","year":"1981","journal-title":"Br J Ophthalmol"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_12_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:05:24Z","timestamp":1787760324000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_12_22"}},"subtitle":["An unusual presentation of renal tuberculosis in a child"],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_12_22","relation":{},"ISSN":["0974-620X"],"issn-type":[{"value":"0974-620X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}