{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:18:56Z","timestamp":1787750336603,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:sec>\n                    <jats:title>AIM:<\/jats:title>\n                    <jats:p>To investigate the prevalence, optical coherence tomography (OCT) features, and visual outcomes in patients with uveitic macular edema (UME).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>This was a retrospective, observational study conducted by a single uvea specialist at a tertiary eye care center in South. We analyzed UME cases at a tertiary eye care center between 2019 and 2024. Demographic data, OCT patterns, and edema thickness and visual acuity were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      We analyzed UME cases at a tertiary eye care center between 2015 and 2019. The mean age was 42.20 \u00b1 29.80 years. Females were more common than males (25:17). UME was found mostly in intermediate uveitis (33, 60%). Cystoid with neurosensory detachment (NSD) was the most common type (24, 42.9%), followed by the cystoid type (22, 39.3%). The mean follow-up duration was 3.75 months. UME thickness was 536.6 \u00b1 375.8 \u03bc before treatment, and posttreatment, it partially resolved to 372.9 \u00b1 367 \u03bc. After treatment, UME completely resolved in 22 (39.2%) cases, partially resolved in 24 (43.6%), remained unchanged in 6 (10.9%), and deteriorated in four (7.3%) eyes. The mean final best-corrected visual acuity was 0.41. A statistically significant difference was observed in the pre- and posttreatment visual acuity and macular edema thickness (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>This study showed that UME is more common in females, occurs in middle age, and is more common in intermediate uveitis. Cystoid with NSD was the most common. Visual acuity improved with treatment in the majority of the cases. Disease-specific outcomes, investigative modalities, and treatment used are the factors influencing assessment and final visual outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_152_25","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T02:00:08Z","timestamp":1782266408000},"page":"239-243","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical profile, optical coherence tomography, and outcomes of uveitic macular edema at a tertiary eye care center in India"],"prefix":"10.4103","volume":"19","author":[{"given":"Jyotirmay","family":"Biswas","sequence":"first","affiliation":[{"name":"Department of Uveitis and Ocular Pathology, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janakiraman","family":"Palani","sequence":"additional","affiliation":[{"name":"Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahana","family":"Sen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sankara Nethralaya, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radha","family":"Annamalai","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parth","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Raman","sequence":"additional","affiliation":[{"name":"Department of Vitreo-Retina, Sankara Nethralaya, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,24]]},"reference":[{"key":"R1-20260624","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ajo.2021.03.061","article-title":"Development of classification criteria for the uveitides","volume":"228","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"R2-20260624","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1136\/bjo.80.4.332","article-title":"Causes and frequency of blindness in patients with intraocular inflammatory disease","volume":"80","author":"Rothova","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"R3-20260624","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1080\/09273948.2018.1529466","article-title":"Uveitic macular edema","volume":"26","author":"Cunningham","year":"2018","journal-title":"Ocul Immunol Inflamm"},{"key":"R4-20260624","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.2147\/OPTH.S180580","article-title":"Macular edema associated with non-infectious uveitis: Pathophysiology, etiology, prevalence, impact and management challenges","volume":"13","author":"Massa","year":"2019","journal-title":"Clin Ophthalmol"},{"key":"R6-20260624","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/eye.2016.115","article-title":"Uveitic macular edema","volume":"30","author":"Fardeau","year":"2016","journal-title":"Eye (Lond)"},{"key":"R7-20260624","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10792-006-9024-7","article-title":"Retinal fluorescein and indocyanine green angiography and optical coherence tomography in successive stages of Vogt-Koyanagi-Harada disease","volume":"27","author":"Fardeau","year":"2007","journal-title":"Int Ophthalmol"},{"key":"R8-20260624","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.ajo.2011.05.028","article-title":"Identifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomography","volume":"152","author":"Sugar","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"R9-20260624","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1007\/s40123-023-00763-4","article-title":"Frequency and treatment regimens of macular edema in 1946 consecutive patients with noninfectious uveitis at a tertiary ophthalmic center in Shaanxi, China","volume":"12","author":"Xue","year":"2023","journal-title":"Ophthalmol Ther"},{"key":"R10-20260624","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.ophtha.2013.09.023","article-title":"Incidence of visual improvement in uveitis cases with visual impairment caused by macular edema","volume":"121","author":"Levin","year":"2014","journal-title":"Ophthalmology"},{"key":"R11-20260624","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3109\/09273948.2012.658467","article-title":"The impact of macular edema on visual function in intermediate, posterior, and panuveitis","volume":"20","author":"Taylor","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"key":"R12-20260624","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.iio.0000155938.83083.94","article-title":"Epidemiology of uveitis","volume":"45","author":"Wakefield","year":"2005","journal-title":"Int Ophthalmol Clin"},{"issue":"Suppl 6","key":"R13-20260624","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.5301\/EJO.2010.6050","article-title":"General pathophysiology of macular edema","volume":"21","author":"Scholl","year":"2011","journal-title":"Eur J Ophthalmol"},{"key":"R14-20260624","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1080\/09273948.2016.1196713","article-title":"Afocus on the epidemiology of uveitis","volume":"26","author":"Tsirouki","year":"2018","journal-title":"Ocul Immunol Inflamm"},{"key":"R15-20260624","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3126\/nepjoph.v10i1.21687","article-title":"Patterns of macular edema in uveitis as diagnosed by optical coherence tomography in tertiary eye center","volume":"10","author":"Gupta","year":"2018","journal-title":"Nepal J Ophthalmol"},{"key":"R16-20260624","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/s12886-024-03447-0","article-title":"Prevalence, clinical characteristics, and independent predictors of uveitic macular edema in an Asian population: A retrospective cohort study","volume":"24","author":"Tungsattayathitthan","year":"2024","journal-title":"BMC Ophthalmol"},{"key":"R17-20260624","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000337234","article-title":"Spectral-domain optical coherence tomography in uveitic macular edema: Morphological features and prognostic factors","volume":"228","author":"Iannetti","year":"2012","journal-title":"Ophthalmologica"},{"key":"R18-20260624","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ajo.2012.06.028","article-title":"Subretinal fluid in uveitic macular edema: Effect on vision and response to therapy","volume":"155","author":"Lehpamer","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"R19-20260624","doi-asserted-by":"crossref","first-page":"e0210799","DOI":"10.1371\/journal.pone.0210799","article-title":"Predictors for functional and anatomic outcomes in macular edema secondary to non-infectious uveitis","volume":"14","author":"Matas","year":"2019","journal-title":"PLoS One"},{"key":"R20-20260624","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12348-021-00266-y","article-title":"Quantitative effect of subretinal fluid and intraretinal edema on visual acuity in uveitic cystoid macular edema","volume":"11","author":"Weldy","year":"2021","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"R21-20260624","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.ophtha.2020.08.035","article-title":"Seven-year outcomes of uveitic macular edema: The multicenter uveitis steroid treatment trial and follow-up study results","volume":"128","author":"Tomkins-Netzer","year":"2021","journal-title":"Ophthalmology"},{"key":"R22-20260624","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0161-6420(99)00087-1","article-title":"Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis","volume":"107","author":"Antcliff","year":"2000","journal-title":"Ophthalmology"},{"key":"R23-20260624","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/ceo.12685","article-title":"Ellipsoid zone on optical coherence tomography: A review","volume":"44","author":"Tao","year":"2016","journal-title":"Clin Exp Ophthalmol"},{"key":"R24-20260624","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ajo.2017.02.017","article-title":"Association of disorganization of retinal inner layers with visual acuity in eyes with uveitic cystoid macular edema","volume":"177","author":"Grewal","year":"2017","journal-title":"Am J Ophthalmol"},{"key":"R25-20260624","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.ophtha.2006.03.027","article-title":"Impact of macular edema on visual acuity in uveitis","volume":"113","author":"Lardenoye","year":"2006","journal-title":"Ophthalmology"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_152_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:25:37Z","timestamp":1787747137000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_152_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_152_25","relation":{},"ISSN":["0974-620X","0974-7842"],"issn-type":[{"value":"0974-620X","type":"print"},{"value":"0974-7842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2025-04-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}