{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:36:26Z","timestamp":1787070986616,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Analysis of safety and efficacy of self-engineered polymethylmethacrylate (Acry C) implants in nonpenetrating glaucoma surgery (NPGS) for control and maintenance of intraocular pressure (IOP) in primary open angle glaucoma (POAG) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS:<\/jats:title>\n                    <jats:p>This was a hospital-based randomized study. Fifty eyes of 50 POAG patients were divided into 3 groups based on preoperative IOP range. NPGS was done with polymethylmethacrylate implants made from haptics of intraocular lenses. All patients were followed up after 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months. Preoperative IOP range was from 25.62 \u00b1 1.72 to 41.66 \u00b1 1.15 mmHg. Postoperative success was defined as IOP &lt;21 mmHg at 1 month in the absence of additional antiglaucoma medication or other treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      A significant reduction in IOP was observed postsurgery in all three groups, changing from a preoperative mean of 25.62 \u00b1 1.72 mmHg, 34.38 \u00b1 2.27 mmHg, and 41.66 \u00b1 1.15 mmHg to a postoperative mean of 13.27 \u00b1 2.13 mmHg, 16.50 \u00b1 2.74 mmHg, and 17.66 \u00b1 1.52 mmHg, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) at 12 months. No significant difference was seen with change in position of the implant, i.e., convexity facing limbus or fornix. No intraoperative complications were observed. The main postoperative complication was failure of filtration in 1 case (3.44%) from Group 1, 5 cases (27.78%) from Group 2, and all 3 cases (100%) from Group 3 at 1 month postoperatively. Thus, 9 eyes (41%) required postoperative antiglaucoma medications following which the IOP was controlled.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>NPGS with Acry-C implants is a safe and cost-effective (&lt;1 US dollar) procedure for control of IOP in POAG patients especially those with moderately elevated IOPs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_192_2015","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T13:37:32Z","timestamp":1716557852000},"page":"16-20","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Self-engineered Acry C plants in nonpenetrating glaucoma surgery"],"prefix":"10.4103","volume":"11","author":[{"given":"Sudhir","family":"Pendke","sequence":"first","affiliation":[{"name":"Depatrment of Ophthalmology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanchit","family":"Bhalgat","sequence":"additional","affiliation":[{"name":"Depatrment of Ophthalmology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250925","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1023\/A:1010745204480","article-title":"Non-penetrating deep sclerectomy and collagen implant surgery in glaucoma patients with advanced field loss","volume":"23","author":"Ates","year":"1999","journal-title":"Int Ophthalmol"},{"key":"R2-20250925","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2174\/1874364101206010059","article-title":"Supraciliary hema implant in combined deep sclerectomy and phacoemulsification: One year results","volume":"6","author":"Bonilla","year":"2012","journal-title":"Open Ophthalmol J"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3928\/1542-8877-20031101-05","article-title":"Comparison of the efficacy and longevity of nonpenetrating glaucoma surgery with and without a new, nonabsorbable hydrophilic implant","volume":"34","author":"Dahan","year":"2003","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1007\/s00417-005-0020-9","article-title":"Non-penetrating deep sclerectomy without or with autologous scleral implant in open-angle glaucoma: Medium-term results","volume":"243","author":"Devloo","year":"2005","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R5-20250925","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1016\/S0886-3350(01)00959-2","article-title":"Deep sclerectomy with collagen implant in patients with glaucoma and high myopia","volume":"27","author":"Hamel","year":"2001","journal-title":"J Cataract Refract Surg"},{"key":"R6-20250925","first-page":"157","article-title":"Deep sclerectomy: Results with and without collagen implant","volume":"20","author":"Sanchez","year":"1996","journal-title":"Int Ophthalmol"},{"key":"R7-20250925","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00061198-200402000-00009","article-title":"T-flux implant versus Healon GV in deep sclerectomy","volume":"13","author":"Ravinet","year":"2004","journal-title":"J Glaucoma"},{"key":"R8-20250925","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/S0886-3350(03)00013-0","article-title":"Conversion from trabeculectomy to deep sclerectomy. Prospective study of the first 44 cases","volume":"29","author":"Drolsum","year":"2003","journal-title":"J Cataract Refract Surg"},{"key":"R9-20250925","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1136\/bjo.85.2.234","article-title":"Non-penetrating glaucoma surgery: The state of play","volume":"85","author":"Tan","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"R10-20250925","first-page":"505","article-title":"The early postoperative complications and cost-effectiveness analysis of non-penetrating trabecular surgery in patients with primary open angle glaucoma","volume":"41","author":"Wang","year":"2005","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"R11-20250925","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1590\/S0004-27492011000600003","article-title":"Resources use, costs and effectiveness of non-penetrating deep sclerectomy according to glaucoma stage","volume":"74","author":"Guedes","year":"2011","journal-title":"Arq Bras Oftalmol"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01408659-201811010-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:58Z","timestamp":1787067598000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01408659-201811010-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_192_2015","relation":{},"ISSN":["0974-620X","0974-7842"],"issn-type":[{"value":"0974-620X","type":"print"},{"value":"0974-7842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}