{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:18:49Z","timestamp":1787847529181,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,5]]},"abstract":"\n CONTEXT:<\/jats:title>\n Emergence of coagulase-negative staphylococci as pathogens in ophthalmia neonatorum.<\/jats:p>\n <\/jats:sec>\n \n AIMS:<\/jats:title>\n To analyze the bacteriological spectrum of ophthalmia neonatorum and its associated risk factors.<\/jats:p>\n <\/jats:sec>\n \n SETTINGS AND DESIGN:<\/jats:title>\n Retrospective analysis in a tertiary care hospital in India.<\/jats:p>\n <\/jats:sec>\n \n SUBJECTS AND METHODS:<\/jats:title>\n A retrospective review was performed in a tertiary care center in India on 139 neonates presenting with conjunctivitis over a period of 3 years. All the neonates presenting to the out-patient department, those admitted in the Neonatal Intensive care Unit and in-patient wards were included in our study. The neonates were clinically examined and followed-up by a single experienced ophthalmologist. Details including demographic data, age of the infant, type of delivery, investigations, and treatment outcomes were analyzed.<\/jats:p>\n <\/jats:sec>\n \n STATISTICAL ANALYSIS USED:<\/jats:title>\n Frequency calculation using Microsoft Excel for windows 10.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n In the 92 samples with growth (66.2%), the most common organisms isolated were coagulase-negative Staphylococci (35.9%),\n Klebsiella pneumoniae<\/jats:italic>\n (16.3%), and\n Acinetobacter<\/jats:italic>\n species (16.3%). Others were\n Staphylococcus aureus<\/jats:italic>\n (14.1%),\n Pseudomonas aeruginosa<\/jats:italic>\n (8.7%), and\n Escherichia coli<\/jats:italic>\n (8.7%). Ophthalmia neonatorum was significantly higher in preterm infants born out of lower-segment cesarean section and those requiring ventilatory support.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Unlike gonococcus, which is implicated in ophthalmia neonatorum, our study shows varied microbiological spectrum and sensitivity patterns with coagulase-negative staphylococci as the key pathogen. The role of coagulase-negative staphylococci as a disease-causing pathogen becomes increasingly important with an imperative need for prudent use of common antibiotics in treating these pathogenic bacteria.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ojo.ojo_22_21","type":"journal-article","created":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T12:13:44Z","timestamp":1624882424000},"page":"85-87","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Pathogenic bacteria and their antibiotic sensitivity in ophthalmia neonatorum"],"prefix":"10.4103","volume":"14","author":[{"given":"Prabhakar","family":"Suhas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Vishnu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Muthayya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20240908","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1755-3768.1984.tb08426.x","article-title":"A study of the incidence of neonatal conjunctivitis and of its bacterial causes including Chlamydia trachomatis. Clinical examination, culture and cytology of tear fluid","volume":"62","author":"M\u00f8lgaard","year":"1984","journal-title":"Acta Ophthalmol (Copenh"},{"key":"R2-5-20240908","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S1522-5720(03)00007-2","article-title":"Medical concerns in the neonatal period","volume":"5","author":"Akera","year":"2003","journal-title":"Clin Family Pract"},{"key":"R3-5-20240908","first-page":"295","article-title":"Microbiological study of neonatal conjunctivitis with special reference to Chlamydia trachomatis","volume":"50","author":"Mohile","year":"2002","journal-title":"Indian J Ophthalmol"},{"key":"R4-5-20240908","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/apa.14227","article-title":"Aetiology of neonatal conjunctivitis evaluated in a population-based setting","volume":"107","author":"Honkila","year":"2018","journal-title":"Acta Paediatr"},{"key":"R5-5-20240908","first-page":"77","article-title":"Neonatal conjunctivitis \u2013 A review","volume":"3","author":"Mallika","year":"2008","journal-title":"Malays Fam Physician"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_22_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:21:16Z","timestamp":1787844076000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_22_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_22_21","relation":{},"ISSN":["0974-620X"],"issn-type":[{"value":"0974-620X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}