{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:36:06Z","timestamp":1791398166243,"version":"4.3.3"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>A 36-year-old male patient presented with a firm swelling in the left lacrimal sac region with a history of recurrent episodes of acute dacryocystitis, which partly resolved with systemic antibiotics. Computed tomography showed diffuse soft tissue mass without bony erosion in the same area. Incisional biopsy confirmed diffuse large cell lymphoma of non-Hodgkin's type by histopathology and immunohistochemistry. Oncologists did not detect systemic involvement, and the patient received six cycles of cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisolone (CHOP). Epiphora was resolved, and no recurrence of the lesion was seen with subsequent dacryocystorhinostomy with intubation and was in good health for up to 3 years of follow-up. Although primary lacrimal sac lymphoma is a rare entity, high suspicion, and prompt action in atypical cases can save lives from aggressive diffuse large cell lymphoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_304_21","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T02:50:51Z","timestamp":1676947851000},"page":"148-150","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis"],"prefix":"10.4103","volume":"16","author":[{"given":"Soma Rani","family":"Roy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murtuza","family":"Nuruddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahmida","family":"Hoque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-34-20240908","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2500\/ar.2015.6.0130","article-title":"Nasolacrimal duct obstruction caused by lymphoproliferative infiltration in the course of chronic lymphocytic leukemia","volume":"6","author":"Litschel","year":"2015","journal-title":"Allergy Rhinol (Providence"},{"key":"R3-34-20240908","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1136\/bjo.2006.090589","article-title":"Primary lymphoma of the lacrimal sac: An EORTC ophthalmic oncology task force study","volume":"90","author":"Sj\u00f6","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"R4-34-20240908","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1159\/000495745","article-title":"Diffuse large B-Cell lymphoma of the lacrimal sac in a Japanese patient","volume":"9","author":"Kakutani","year":"2018","journal-title":"Case Rep Ophthalmol"},{"key":"R5-34-20240908","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s00417-003-0831-5","article-title":"Prognostic value of cell-cycle markers in ocular adnexal lymphoma: An assessment of 230 cases","volume":"242","author":"Coupland","year":"2004","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R6-34-20240908","doi-asserted-by":"crossref","first-page":"118","DOI":"10.5858\/2008-132-118-DLBL","article-title":"Diffuse large B-cell lymphoma","volume":"132","author":"Hunt","year":"2008","journal-title":"Arch Pathol Lab Med"},{"key":"R7-34-20240908","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/01.IOP.0000159173.42243.AD","article-title":"Lymphoproliferative disease of the ocular adnexa: A clinical and pathologic study with statistical analysis of 69 patients","volume":"21","author":"Sullivan","year":"2005","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"R8-34-20240908","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/01.IOP.0000115594.98470.AC","article-title":"Monoclonal antibody treatment of orbital lymphoma","volume":"20","author":"Sullivan","year":"2004","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"R9-34-20240908","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/eye.2009.283","article-title":"Ocular adnexal diffuse large B-cell lymphoma: Local disease correlates with better outcomes","volume":"24","author":"Madge","year":"2010","journal-title":"Eye (Lond"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_304_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:06:45Z","timestamp":1787760405000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_304_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_304_21","relation":{},"ISSN":["0974-620X"],"issn-type":[{"value":"0974-620X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}