{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:43:19Z","timestamp":1788964999263,"version":"build-2803163510"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>A 4\u00bd-year-old boy presented to the ophthalmology clinic with intermittent left eye (LE) redness, protrusion, and reduced LE vision. He was noticed to have multiple skin hyperpigmented lesions increasing in size and number since birth. Clinically diagnosed as neurofibromatosis (NF)-type I associated with LE glaucoma, axial myopia, and amblyopia. He was started on topical timolol eye drops, then switched his timolol to latanoprost due to parasomnia (sleep disturbances and sleepwalking), and his symptoms improved significantly within 6 weeks with controlled intraocular pressure. NF-1 is a congenital multisystemic disease which needs special attention and continuous monitoring. Unilateral glaucoma is not a common association but can be the presenting ophthalmic manifestation. Multidisciplinary management is crucial for these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_34_22","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T02:50:51Z","timestamp":1676947851000},"page":"106-109","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["First unilateral glaucoma in an Omani boy with neurofibromatosis type 1 initially presented as proptosis with ectropion uvea"],"prefix":"10.4103","volume":"16","author":[{"given":"Asaad","family":"Al-Habsi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nouf","family":"Al-Farsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-22-20240908","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2008.12.051","article-title":"Neurofibromatosis type 1","volume":"61","author":"Boyd","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"R2-22-20240908","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1016\/S0161-6420(83)34371-2","article-title":"Ocular neurofibromatosis","volume":"90","author":"Brownstein","year":"1983","journal-title":"Ophthalmology"},{"key":"R3-22-20240908","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1001\/archopht.1968.03850040129003","article-title":"Distinctive gonioscopic findings in glaucoma due to neurofibromatosis","volume":"79","author":"Grant","year":"1968","journal-title":"Arch Ophthalmol"},{"key":"R4-22-20240908","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/GIM.0b013e3181bf15e3","article-title":"Clinical and genetic aspects of neurofibromatosis 1","volume":"12","author":"Jett","year":"2010","journal-title":"Genet Med"},{"key":"R5-22-20240908","doi-asserted-by":"crossref","first-page":"137","DOI":"10.4103\/ejos.ejos_52_19","article-title":"Unilateral congenital glaucoma may be the earliest presenting: Sign of orbitofacial neurofibromatosis and intracranial lesions: A case series","volume":"112","author":"Zayeda","year":"2020","journal-title":"J Egypt Ophthalmol Soc"},{"key":"R6-22-20240908","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/j.ophtha.2009.06.019","article-title":"Glaucoma and globe enlargement associated with neurofibromatosis type 1","volume":"116","author":"Morales","year":"2009","journal-title":"Ophthalmology"},{"key":"R8-22-20240908","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10792-009-9307-x","article-title":"Management of congenital glaucoma in neurofibromatosis type 1: A report of two cases","volume":"30","author":"Col\u00e1s-Tom\u00e1s","year":"2010","journal-title":"Int Ophthalmol"},{"key":"R9-22-20240908","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.ophtha.2012.01.027","article-title":"Congenital ectropion uvea and mechanisms of glaucoma in neurofibromatosis type 1: New insights","volume":"119","author":"Edward","year":"2012","journal-title":"Ophthalmology"},{"key":"R10-22-20240908","doi-asserted-by":"crossref","first-page":"92","DOI":"10.5005\/jp-journals-10008-1192","article-title":"Review on the management of primary congenital glaucoma","volume":"9","author":"Yu Chan","year":"2015","journal-title":"J Curr Glaucoma Pract"},{"key":"R11-22-20240908","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1525-1470.2011.01664.x","article-title":"Timolol maleate 0.5% or 0.1% gel-forming solution for infantile hemangiomas: A retrospective, multicenter, cohort study","volume":"29","author":"Chakkittakandiyil","year":"2012","journal-title":"Pediatr Dermatol"},{"key":"R12-22-20240908","doi-asserted-by":"crossref","first-page":"7.e5","DOI":"10.1016\/j.genhosppsych.2010.04.008","article-title":"Sleep disorders, nightmares, depression and anxiety in an elderly patient treated with low-dose metoprolol","volume":"32","author":"Ahmed","year":"2010","journal-title":"Gen Hosp Psychiatry"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_34_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:06:17Z","timestamp":1787760377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_34_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_34_22","relation":{},"ISSN":["0974-620X"],"issn-type":[{"value":"0974-620X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}