{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:37:18Z","timestamp":1787319438099,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>The purpose of this study was to assess the safety and efficacy of large-scale use of vancomycin injection in an infusion bottle during vitreoretinal procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS:<\/jats:title>\n                    <jats:p>This was a retrospective evaluation of all vitreoretinal procedures done in the last 70 months, where intraoperatively vancomycin injection (0.2 mg\/mL) was used in an infusion bottle prophylactically as standard care. Vitreoretinal procedures were categorized as major (duration &gt;30 min), minor (duration &lt;30 min), and silicone oil removal. Postoperatively, a detailed ocular examination was done to rule out hemorrhagic occlusive retinal vasculitis (HORV) or signs of postoperative bacterial endophthalmitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Over the last 70 months, a total of 31,720 vitreoretinal procedures were performed, which included 24,371 major vitreoretinal procedures, 1401 minor vitreoretinal procedures, and 5948 silicone oil removal cases. None of these cases developed HORV or bacterial endophthalmitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Vancomycin (0.2 mg\/mL) in infusion fluid during vitreoretinal procedures is safe and can be advocated as a prophylactic measure against postvitrectomy bacterial infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_39_24","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T01:02:42Z","timestamp":1719450162000},"page":"234-236","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy and safety of large-scale use of vancomycin injection in infusion bottle during vitreoretinal procedures"],"prefix":"10.4103","volume":"17","author":[{"given":"Subhendu Kumar","family":"Boral","sequence":"first","affiliation":[{"name":"Department of Vitreoretina, Disha Eye Hospitals Pvt Ltd, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, Siliguri Greater Lions Eye Hospital, Siliguri, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnab","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Cataract and Refractive Surgery, Disha Eye Hospitals Pvt Ltd, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debdulal","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, Disha Eye Hospitals Pvt Ltd, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santanu","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, Disha Eye Hospitals Pvt Ltd, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar Kanti","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Vitreoretina, Disha Eye Hospitals Pvt Ltd, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,27]]},"reference":[{"key":"R1-20260507","doi-asserted-by":"crossref","first-page":"321","DOI":"10.2147\/OPTH.S9546","article-title":"Intracameral vancomycin following cataract surgery: An eleven-year study","volume":"4","author":"Anijeet","year":"2010","journal-title":"Clin Ophthalmol"},{"key":"R2-20260507","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.ophtha.2015.03.016","article-title":"Postoperative hemorrhagic occlusive retinal vasculitis: Expanding the clinical spectrum and possible association with vancomycin","volume":"122","author":"Witkin","year":"2015","journal-title":"Ophthalmology"},{"key":"R3-20260507","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1186\/s12879-016-1830-6","article-title":"Vancomycin in infusion during vitrectomy in surgical treatment of acute postoperative and posttraumatic endophthalmitis","volume":"16","author":"Rejdak","year":"2016","journal-title":"BMC Infect Dis"},{"key":"R4-20260507","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.ophtha.2016.11.042","article-title":"Vancomycin-associated hemorrhagic occlusive retinal vasculitis: Clinical characteristics of 36 eyes","volume":"124","author":"Witkin","year":"2017","journal-title":"Ophthalmology"},{"key":"R5-20260507","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/00006982-199515050-00010","article-title":"Vancomycin levels after intravitreal injection. Effects of inflammation and surgery","volume":"15","author":"Aguilar","year":"1995","journal-title":"Retina"},{"key":"R6-20260507","first-page":"3169","article-title":"Measurement of volume of vitreous space during vitrectomy","volume":"50","author":"Tanaka","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R7-20260507","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/j.1442-9071.2009.02132.x","article-title":"Anterior chamber volume measurements with visante optical coherence tomography and pentacam: Repeatability and level of agreement","volume":"37","author":"Labiris","year":"2009","journal-title":"Clin Exp Ophthalmol"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_39_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:43:10Z","timestamp":1786650190000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_39_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_39_24","relation":{},"ISSN":["0974-620X","0974-7842"],"issn-type":[{"value":"0974-620X","type":"print"},{"value":"0974-7842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"2024-02-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}