{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:51Z","timestamp":1787772351285,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Endogenous fungal endophthalmitis caused by an unusual fungus poses both diagnostic and therapeutic challenges. We report a case of endogenous endophthalmitis caused by a rare mold, namely\n                      <jats:italic toggle=\"yes\">Cladosporium<\/jats:italic>\n                      spp., which presented with a foveal abscess. A 52-year-old male patient who was diagnosed with rectal carcinoma presented with pain, redness, and a loss of vision in the right eye. He had been experiencing the symptoms for 1 week. The patient had undergone gastrointestinal surgery 2 weeks before experiencing the eye complaint. His best-corrected visual acuity was hand movements. Fundus examination revealed a foveal abscess of around a half-disc diameter in size that simulated retinochoroiditis with vitritis. Optical coherence tomography of the macula revealed a hyperreflective lesion in the fovea, which breached the full thickness of the fovea and extended into the preretinal space. Ocular toxoplasmosis was considered. On that basis, oral trimethoprim\/sulfamethoxazole was given for 1 week, although the patient's condition worsened. A vitreous tap and an intravitreal combination of vancomycin, ceftazidime, and amphotericin B were administered twice but did not improve the patient's condition. Pars plana vitrectomy was performed and the vitreous biopsy results revealed the presence of\n                      <jats:italic toggle=\"yes\">Cladosporium<\/jats:italic>\n                      spp. Intravitreal voriconazole was given three times and the foveal abscess resolved into a scar. Endophthalmitis caused by\n                      <jats:italic toggle=\"yes\">Cladosporium<\/jats:italic>\n                      spp. is uncommon and published case reports are extremely limited. The present case may provide insight into the variable presentation of fungal endophthalmitis and, therefore, assist with the early diagnosis and appropriate management of the condition.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_459_20","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T13:49:17Z","timestamp":1716558557000},"page":"379-381","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Cladosporium spp. endogenous endophthalmitis simulating the classic \u201cheadlight-in-the-fog\u201d appearance of active toxoplasmosis"],"prefix":"10.4103","volume":"15","author":[{"given":"Abbas Abd","family":"Hamid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia Lim","family":"Lay Suan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanizasurana","family":"Hashim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zabri","family":"Kamarudin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julieana","family":"Muhammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-26-20240908","first-page":"95","article-title":"Endophthalmitis: State of the art","volume":"9","author":"Vaziri","year":"2015","journal-title":"Clin Ophthalmol"},{"key":"R2-26-20240908","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12348-020-00208-0","article-title":"Infectious endophthalmitis at a Philippine tertiary hospital: A ten-year retrospective study","volume":"10","author":"Dimacali","year":"2020","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"R3-26-20240908","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0002-9343(89)80392-4","article-title":"Risk factors for nosocomial candidemia: A case-control study in adults without leukemia","volume":"87","author":"Bross","year":"1989","journal-title":"Am J Med"},{"key":"R4-26-20240908","first-page":"183","article-title":"A comparative clinicopathologic study of endogenous mycotic endophthalmitis: Variations in clinical and histopathologic changes in candidiasis compared to aspergillosis","volume":"98","author":"Rao","year":"2000","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R5-26-20240908","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1080\/09273948.2019.1691239","article-title":"Cladosporium endogenous endophthalmitis mimicking toxoplasma retinochoroiditis","volume":"29","author":"Singh","year":"2021","journal-title":"Ocul Immunol Inflamm"},{"key":"R6-26-20240908","first-page":"267","article-title":"Infectious crystalline keratopathy caused by Cladosporium sp. after penetrating keratoplasty: A case report","volume":"9","author":"Stock","year":"2016","journal-title":"Int Med Case Rep J"},{"key":"R7-26-20240908","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s12886-015-0092-1","article-title":"Cladosporium keratitis-A case report and literature review","volume":"15","author":"Cheng","year":"2015","journal-title":"BMC Ophthalmol"},{"key":"R8-26-20240908","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1097\/IAE.0000000000001727","article-title":"Role of early vitrectomy in the treatment of fungal endophthalmitis","volume":"38","author":"Behera","year":"2018","journal-title":"Retina"},{"key":"R9-26-20240908","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1097\/01.iae.0000250011.68532.a2","article-title":"Intravitreal voriconazole for drug-resistant fungal endophthalmitis: Case series","volume":"26","author":"Sen","year":"2006","journal-title":"Retina"},{"key":"R10-26-20240908","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1023\/A:1010954803886","article-title":"In vitro antifungal activities of voriconazole and reference agents as determined by NCCLS methods: Review of the literature","volume":"150","author":"Espinel-Ingroff","year":"2001","journal-title":"Mycopathologia"}],"container-title":["Oman Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_459_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:40:29Z","timestamp":1787769629000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ojo.ojo_459_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ojo.ojo_459_20","relation":{},"ISSN":["0974-620X"],"issn-type":[{"value":"0974-620X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}