{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:27:50Z","timestamp":1787772470996,"version":"build-2784847793"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>AIM:<\/jats:title>\n                    <jats:p>To analyze choroidal parameters in eyes with diabetic macular edema (DME) treated with intravitreal Ozurdex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>Twenty eyes of 14 patients were included in this prospective study. Optical coherence tomography images were obtained before and 8\u201310 weeks after intravitreal Ozurdex injection; binarized and subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Mean SFCT (treatment na\u00efve; 242.22 \u00b1 32.87 reduced to 218.10 \u00b1 22.10,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.158 and previously treated; 330.4 \u00b1 56.72 reduced to 328.93 \u00b1 50.55,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.833) and mean CVI (treatment na\u00efve; 0.64 \u00b1 0.03 changed to 0.65 \u00b1 0.04,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.583 and previously treated; 0.65 \u00b1 0.05 reduced to 0.64 \u00b1 0.03,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.208) showed no significant change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Intravitreal Ozurdex showed no significant effects on SFCT and CVI in eyes with DME over short term. Larger studies with longer follow-up may allow a better understanding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_7_21","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T13:44:37Z","timestamp":1716558277000},"page":"179-183","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Intravitreal Ozurdex has no short term influence on choroidal thickness and vascularity index in eyes with diabetic macular edema"],"prefix":"10.4103","volume":"14","author":[{"given":"Pukhraj","family":"Rishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupesh","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rekha Priya","family":"Kalluri Bharat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekta","family":"Rishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240908","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.ajo.2008.10.005","article-title":"Enhanced depth imaging optical coherence tomography of retinal pigment epithelial detachment in age-related macular degeneration","volume":"147","author":"Spaide","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"R2-11-20240908","doi-asserted-by":"crossref","first-page":"21090","DOI":"10.1038\/srep21090","article-title":"Choroidal vascularity index as a measure of vascular status of the choroid: Measurements in healthy eyes from a population-based study","volume":"6","author":"Agrawal","year":"2016","journal-title":"Sci Rep"},{"key":"R3-11-20240908","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1167\/iovs.14-14933","article-title":"Choroidal thickness in geographic atrophy secondary to age-related macular degeneration","volume":"56","author":"Lindner","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R4-11-20240908","doi-asserted-by":"crossref","first-page":"e585","DOI":"10.1111\/aos.12631","article-title":"Choroidal thickness and high myopia: A case-control study of young Chinese men in Singapore","volume":"93","author":"Gupta","year":"2015","journal-title":"Acta Ophthalmol"},{"key":"R5-11-20240908","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1007\/s00417-011-1620-1","article-title":"Subfoveal choroidal thickness in typical age-related macular degeneration and polypoidal choroidal vasculopathy","volume":"249","author":"Koizumi","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R6-11-20240908","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.ajo.2008.05.032","article-title":"Enhanced depth imaging spectral-domain optical coherence tomography","volume":"146","author":"Spaide","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"R7-11-20240908","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0014-4835(73)90185-1","article-title":"Ocular and optic nerve blood flow at normal and increased intraocular pressures in monkeys (Macaca irus): A study with radioactively labelled microspheres including flow determinations in brain and some other tissues","volume":"15","author":"Alm","year":"1973","journal-title":"Exp Eye Res"},{"key":"R8-11-20240908","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.exer.2004.01.011","article-title":"Ultrahigh resolution optical coherence tomography of the monkey fovea. 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