{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:36:38Z","timestamp":1787070998172,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>The purpose of this study was to determine the incidence, severity, and associated risk factors of retinopathy of prematurity (ROP) in a district in South India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>This was a prospective, observational, cohort study involving babies at risk of ROP conducted in five Neonatal Intensive Care Units in a district in Tamil Nadu, South India. All babies with gestational age at birth of \u226436 weeks and a birth weight (BW) of \u22641900 g with a follow-up period of at least 6 months were enrolled for the study. Neonatal and maternal risk factors were assessed and univariate and multivariate logistic regression analysis performed to examine the predictors of ROP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>A total of 325 infants were screened. ROP was identified in 210 eyes of 106 (32.6%) babies with severe ROP (stage \u22653 ROP) occurring in 14 (13.2%) babies. Low BW (LBW) was the only significant risk factor for ROP on multivariate logistic regression analysis. The mean BW was 1285 and 1452 g for babies with and without ROP, respectively. Treatment was indicated in 22 eyes of 14 (13.2%) infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The incidence of ROP was fairly high and strongly associated with LBW. A relatively low incidence of severe ROP was, however, observed. More effort is, therefore, required towards the prevention of preterm births while the present gains in neonatal care should be sustained to reduce the incidence of ROP and thus childhood blindness in the country.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ojo.ojo_97_2016","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T13:37:32Z","timestamp":1716557852000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":33,"title":["Risk factors for retinopathy of prematurity in a district in South India: A prospective cohort study"],"prefix":"10.4103","volume":"11","author":[{"given":"Ashish A.","family":"Ahuja","sequence":"first","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yerahaia C.","family":"V. Reddy","sequence":"additional","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olukorede O.","family":"Adenuga","sequence":"additional","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, India"},{"name":"Department of Ophthalmology, Jos University Teaching Hospital, Jos, Plateau State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheeraj","family":"Kewlani","sequence":"additional","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meenakshi","family":"Ravindran","sequence":"additional","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rengappa","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Retina Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"Suppl 1","key":"R1-20250925","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/pr.2013.205","article-title":"Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010","volume":"74","author":"Blencowe","year":"2013","journal-title":"Pediatr Res"},{"key":"R2-20250925","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1542\/peds.2004-1413","article-title":"The incidence and course of retinopathy of prematurity: Findings from the early treatment for retinopathy of prematurity study","volume":"116","author":"Good","year":"2005","journal-title":"Pediatrics"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.clp.2013.02.001","article-title":"Retinopathy of prematurity-incidence today","volume":"40","author":"Zin","year":"2013","journal-title":"Clin Perinatol"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1471-2431-5-18","article-title":"Retinopathy of prematurity and risk factors: A prospective cohort study","volume":"5","author":"Karna","year":"2005","journal-title":"BMC Pediatr"},{"key":"R5-20250925","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0161-6420(91)32074-8","article-title":"Incidence and early course of retinopathy of prematurity. 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