{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:24:53Z","timestamp":1787765093990,"version":"build-2784847793"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>Type 1 diabetes mellitus (T1DM) is a chronic disease, mainly observed in children or youth, with a significantly increased incidence in young children. Structured therapeutic patient education (TPE) is a must to help them manage their disease effectively and lead a healthy lifestyle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>This study aimed to assess the effects of a structured TPE program on glycemic markers and quality of life (QOL) of T1DM children and adolescents in Fez city, Morocco.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>It is a quasi-experimental study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>One hundred T1DM children and adolescents, aged 8\u201318, participated in a TPE intervention at the pediatric department in a hospital center in Fez, Morocco. Glycemic markers were measured and QOL was assessed by a validated questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>\n                      Parametric and nonparametric tests were used and statistical significance determined by\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At 3 months\u2019 follow-up, both global and dimensional QOL mean scores improved significantly (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2264 0.0001), whereas glycosylated hemoglobin (HbA1c) decreased (10.28% vs. 10.62%), tough with no statistical significance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.160). Furthermore, a significant improvement was observed in the maximum preprandial (2, 11 g\/L [1.51\u20132.58] vs. 2, 37 g\/L [1.81\u20133.21],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) and postprandial blood glucose levels (2, 50 g\/L [1.90\u20133.27] vs. 2, 95 g\/L [2.07\u20133.99],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) after 3 months; with no significant change in their minimum.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although this TPE intervention was more effective in improving patients\u2019 QOL than their HbA1c, it is worth striving to implement regular TPE programs for T1DM pediatric patients and adjust them to achieve a better patients\u2019 glycemic markers levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/picr.picr_80_23","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T05:00:25Z","timestamp":1704776425000},"page":"24-30","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Effects of therapeutic patient education program on glycemic control and quality of life among children and adolescents with type 1 diabetes mellitus in Fez city, Morocco"],"prefix":"10.4103","volume":"15","author":[{"given":"Hana\u00e2","family":"Ait-Taleb Lahsen","sequence":"first","affiliation":[{"name":"Department of Biology, LSNAMOPEQ, Faculty of Sciences Dhar El Mahraz Fsdm, Sidi Mohamed Ben Abdellah University, Fez, Morocco"},{"name":"High Institute of Nursing and Technical Health Professions, Fez ISPITS, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed El Amine","family":"Ragala","sequence":"additional","affiliation":[{"name":"Department of Biology, LSNAMOPEQ, Faculty of Sciences Dhar El Mahraz Fsdm, Sidi Mohamed Ben Abdellah University, Fez, Morocco"},{"name":"Department of Biology, High School Teachers-Training College (Ecole Normale Superieure), Sidi Mohamed Ben Abdellah University, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanane","family":"El Abed","sequence":"additional","affiliation":[{"name":"Department of Biology, LSNAMOPEQ, Faculty of Sciences Dhar El Mahraz Fsdm, Sidi Mohamed Ben Abdellah University, Fez, Morocco"},{"name":"High Institute of Nursing and Technical Health Professions, Fez ISPITS, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Btissame","family":"Zarrouq","sequence":"additional","affiliation":[{"name":"Department of Biology, High School Teachers-Training College (Ecole Normale Superieure), Sidi Mohamed Ben Abdellah University, Fez, Morocco"},{"name":"Laboratory of Epidemiology and Research in Health Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karima","family":"Halim","sequence":"additional","affiliation":[{"name":"Department of Biology, LSNAMOPEQ, Faculty of Sciences Dhar El Mahraz Fsdm, Sidi Mohamed Ben Abdellah University, Fez, Morocco"},{"name":"Department of Biology, High School Teachers-Training College (Ecole Normale Superieure), Sidi Mohamed Ben Abdellah University, Fez, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"issue":"Suppl 27","key":"R1-20240829","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/pedi.12698","article-title":"ISPAD clinical practice consensus guidelines 2018:Assessment and management of hypoglycemia in children and adolescents with diabetes","volume":"19","author":"Abraham","year":"2018","journal-title":"Pediatr Diabetes"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"248","DOI":"10.5114\/hpc.2019.84190","article-title":"Awareness among nursing students about care for children with type 1 diabetes","volume":"13","author":"\u0141awnik","year":"2019","journal-title":"HPC"},{"key":"R4-20240829","first-page":"3","article-title":"Diab\u00e8te de l'enfant:Difficult\u00e9de prise en charge (\u00e0propos de 85 cas)","volume":"3","author":"Toufiki","year":"2008"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/PL00008413","article-title":"Parental information needs in chronic renal failure and diabetes mellitus","volume":"160","author":"Collier","year":"2001","journal-title":"Eur J Pediatr"},{"issue":"Suppl 20","key":"R7-20240829","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/pedi.12187","article-title":"ISPAD clinical practice consensus guidelines 2014. 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