{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:18:07Z","timestamp":1790018287218,"version":"4.0.1"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and purpose:<\/jats:title>\n                    <jats:p>\n                      In traditional medicine, species of\n                      <jats:italic toggle=\"yes\">Cleome<\/jats:italic>\n                      (known in Persian as alaf-e-mar) are used to treat wounds and earaches, as well as for their antihelmintic, carminative, and anti-arthritic properties. Flavonoids, among the most significant phytochemicals in this family, hold pharmacological importance, mainly due to their ability to scavenge free radicals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Experimental approach:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Cleome turkmena<\/jats:italic>\n                      Bobrov was collected and extracted in methanol. Compounds were isolated by open-column and size-exclusion chromatography. Free radical scavenging ability and reduction potential of isolated flavonols along with allantoin were determined according to the scavenging of the DPPH (diphenyl-picrylhydrazyl) radical and reducing power of Fe\n                      <jats:sup>3<\/jats:sup>\n                      + assays. A theoretical study of their antioxidant capacity was done using density functional theory calculations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings\/Results:<\/jats:title>\n                    <jats:p>Allantoin (compound 1), 2 known flavonol glycosides (compounds 2, 4), and 1 undescribed flavonol glycoside (compound 3) were isolated, and their structures were identified using different spectroscopic techniques for the first time in this plant. Among them, compound 4, quercitin-3-O-\u03b2-D-glucoside-7-O-\u03b1-L-rhamnoside, exhibited the best free radical scavenging and reducing power effects compared to the standards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and implications:<\/jats:title>\n                    <jats:p>\n                      All flavone glycosides isolated from\n                      <jats:italic toggle=\"yes\">Cleome turkmena<\/jats:italic>\n                      Bobrov showed favorable DPPH radical scavenging and Fe\n                      <jats:sup>3<\/jats:sup>\n                      + reducing power.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/rps.rps_266_23","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T15:00:19Z","timestamp":1766847619000},"page":"64-76","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Experimental and theoretical evaluation of antioxidant capacity of flavone glycosides extracted from Cleome turkmena Bobrov"],"prefix":"10.4103","volume":"21","author":[{"given":"Mehrdad Mohammadpour","family":"Dehkordi","sequence":"first","affiliation":[{"name":"Department of Medicinal Chemistry, Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham","family":"Elahi","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samin","family":"Mousavi","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R. Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Abdeyazdan","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R. 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