{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:38Z","timestamp":1786649678629,"version":"build-2736575974"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In this prospective observational study, we aimed to determine the perioperative incidence and the risk factors of acute kidney injury after elective major abdominal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Adult patients who had undergone major elective abdominal surgery were included in the study. The patients were divided into Group AKI + and Group AKI, according to KDIGO criteria at 48 hours. Patients\u2019 demographic data, preoperative status, and laboratory data, operation-related data, and postoperative laboratory and follow-up data were noted. The patients were followed up for complications and mortality within three months after the operation date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In 425 patients included in the statistical analysis, the incidence of acute kidney injury after elective major abdominal surgery in our hospital was found to be 11.52% (49\/425). In the multivariate analysis, postoperative continuation of vasopressor, mean arterial pressure &lt;50 mmHg for at least 5 minutes, intraoperative 6% hydroxy-ethyl starch use, and high body mass index were found to be independent risk factors, in order of importance in increasing risk (OR 5.1, CI [1.4\u201318.9],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0,016; OR 3.9, CI [1.3\u201311.6],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0,014; OR 2.7, CI [1.1\u20136.8],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0,029; OR 1.2, CI [1.1\u20131.2],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0,001, respectively). 30- and 90-day mortality was found more frequently in patients who developed acute kidney injury.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In this study, we recommend modifying risk factors if possible, including avoiding 6% HES use and close blood pressure monitoring to reduce the incidence of postoperative acute kidney injury.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sja.sja_187_25","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T12:01:12Z","timestamp":1756900872000},"page":"526-534","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Risk factors of acute kidney injury after major elective abdominal surgery: A prospective observational study"],"prefix":"10.4103","volume":"19","author":[{"given":"Dilan","family":"Buyuk","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Private Anatolia Hospital Lara, Antalya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esin A.","family":"Sonmez","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Dr. Suleyman Yalcin City Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demet A.","family":"Bingol","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulay O.","family":"Seyhan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukadder O.","family":"Sungur","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Istanbul University, Istanbul Faculty of Medicine, 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