{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:58:58Z","timestamp":1787169538125,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Walker-Warburg syndrome is a rare autosomal recessive congenital muscular dystrophy presenting with hydrocephalus, type II lissencephaly, cerebellar malformation, and ocular anomalies. Here, we describe the use of perioperative total intravenous anesthesia in a pediatric patient with Walker-Walburg syndrome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Features:<\/jats:title>\n                    <jats:p>A 2-month-old girl with Walker-Walburg syndrome was admitted for urgent ventriculoperitoneal shunt insertion. Anesthesia was induced using intravenous atropine (100 \u03bcg), ketamine (10 mg), and fentanyl (15 \u03bcg). The patient was monitored for various clinical parameters based on American Society of Anesthesiologists standards. Anesthesia was maintained using intermittent doses of 0.5 mg intravenous midazolam and 5\u201310 \u03bcg fentanyl in incremental boluses. The postoperative course was uneventful.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>To our knowledge, no published cases have reported the use of total intravenous anesthesia in patients with Walker-Walburg syndrome who have potential risks for anesthetic-induced malignant hyperthermia. This report described the key features, potential anesthetic management plan, and current literature review of Walker-Walburg syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sja.sja_529_21","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T02:03:04Z","timestamp":1647568984000},"page":"217-220","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative total intravenous anesthesia in a child with Walker-Warburg syndrome"],"prefix":"10.4103","volume":"16","author":[{"given":"Wadeeah","family":"Bahaziq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed R.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majd Y.","family":"Jubili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz","family":"Boker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-16-20240909","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1750-1172-1-29","article-title":"Walker-Warburg syndrome","volume":"1","author":"Vajsar","year":"2006","journal-title":"Orphanet J Rare Dis"},{"key":"R2-16-20240909","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/ajmg.1320320213","article-title":"Diagnostic criteria for Walker-Warburg syndrome","volume":"32","author":"Dobyns","year":"1989","journal-title":"Am J Med Genet"},{"key":"R3-16-20240909","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/ajmg.1320270306","article-title":"Walker-Warburg syndrome with cleft lip and cleft palate in two sibs","volume":"27","author":"Burton","year":"1987","journal-title":"Am J Med Genet"},{"key":"R4-16-20240909","doi-asserted-by":"crossref","first-page":"E54","DOI":"10.1055\/s-0036-1582303","article-title":"Very early in-utero diagnosis of Walker-Warburg phenotype: The cutting edge of technology","volume":"2","author":"Achiron","year":"2016","journal-title":"Ultrasound Int Open"},{"key":"R5-16-20240909","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/uog.15735","article-title":"Prenatal diagnosis of cobblestone lissencephaly associated with Walker\u2013Warburg syndrome based on a specific sonographic pattern","volume":"47","author":"Lacalm","year":"2016","journal-title":"Ultrasound Obstet Gynecol"},{"key":"R7-16-20240909","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bjan.2012.12.002","article-title":"Anesthesia for a child with Walker-Warburg syndrome","volume":"64","author":"Kose","year":"2014","journal-title":"Braz J Anesthesiol"},{"key":"R8-16-20240909","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.29271\/jcpsp.2020.10.1115","article-title":"Anaesthesia management of a new-born baby with Walker-Warburg syndrome undergoing ventriculoperitoneal shunt insertion","volume":"30","author":"Yasir","year":"2020","journal-title":"J Coll Physicians Surg Pak"},{"key":"R9-16-20240909","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/ccr3.334","article-title":"Perioperative considerations in Walker\u2013Warburg syndrome","volume":"3","author":"Valk","year":"2015","journal-title":"Clin Case Rep"},{"key":"R10-16-20240909","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/ACO.0b013e3283393977","article-title":"Can inhalation agents be used in the presence of a child with myopathy?","volume":"23","author":"Veyckemans","year":"2010","journal-title":"Curr Opin Anaesthesiol"},{"key":"R11-16-20240909","first-page":"355","article-title":"Management of malignant hyperthermia: Diagnosis and treatment","volume":"10","author":"Schneiderbanger","year":"2014","journal-title":"Ther Clin Risk Manag"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_529_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:08:35Z","timestamp":1787166515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_529_21"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/sja.sja_529_21","relation":{},"ISSN":["1658-354X"],"issn-type":[{"value":"1658-354X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}