{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:45Z","timestamp":1787071065258,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,4]]},"abstract":"\n Objective:<\/jats:title>\n The objective of this study is to evaluate the postoperative analgesic effect of a combination of ropivacaine and dexmedetomidine for ultrasound-guided fascia iliaca compartment block (FICB) after knee arthroscopy.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Forty patients scheduled for knee arthroscopy were randomized to receive either 30 ml of 0.25% ropivacaine alone (Group A,\n n<\/jats:italic>\n = 20) or combined with dexmedetomidine 1 \u03bcg\/kg (Group B,\n n<\/jats:italic>\n = 20). Pain intensity was evaluated using the visual analogue scale (VAS), at rest and during activity at 4, 6, 8, 12, and 24 h after surgery. Level of consciousness was evaluated using the Ramsay sedation score. Time to first analgesic request after surgery, the dose of analgesic used in the first 24 h after surgery, variation of heart rate, and adverse reactions were also recorded.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n VAS scores at 6 and 12 h after surgery were significantly lower in Group B compared to Group A (\n P<\/jats:italic>\n < 0.05). No significant difference was observed in the Ramsay sedation score or time to first analgesic request after surgery (\n P<\/jats:italic>\n > 0.05). The total dose of analgesic used in the first 24 h after surgery was higher in Group A than in Group B. The incidence of bradycardia was higher in Group B compared to Group A. No adverse reactions were observed in either group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n FICB with a combination of ropivacaine and dexmedetomidine resulted in significant reduction of VAS scores with lower postoperative analgesic requirement after arthroscopic knee surgery. No adverse reactions or complications were noted except for lower heart rate in Group B patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/sja.sja_533_18","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T06:40:34Z","timestamp":1682318434000},"page":"100-105","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Postoperative analgesia with ropivacaine and dexmedetomidine for ultrasound-guided fascia iliaca compartment block after arthroscopic knee surgery"],"prefix":"10.4103","volume":"13","author":[{"given":"Ying","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Jiangyin Hospital, Affiliated to Southeast University Medical School, Jiangyin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangyin Hospital, Affiliated to Southeast University Medical School, Jiangyin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laiyou","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangyin Hospital, Affiliated to Southeast University Medical School, Jiangyin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianqing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangyin Hospital, Affiliated to Southeast University Medical School, Jiangyin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Jiangyin Hospital, Affiliated to Southeast University Medical School, Jiangyin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250925","first-page":"UC13","article-title":"Analgesic efficacy of ultrasound guided FICB in 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central nervous blockade: A randomized trial","volume":"39","author":"Diakomi","year":"2014","journal-title":"Reg Anesth Pain Med"},{"key":"R11-20250925","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/joacp.JOACP_205_16","article-title":"Evaluation of dexmedetomidine and fentanyl as additives to ropivacaine for epidural anesthesia and postoperative analgesia","volume":"34","author":"Kiran","year":"2018","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"R12-20250925","first-page":"1330","article-title":"Efficacy of fascia iliaca compartment block with dexmedetomidine combined with ropivacaine for analgesia in patients suffering from proximal femoral fractures","volume":"34","author":"Sun","year":"2014","journal-title":"Chin J Anesthesiol"},{"key":"R13-20250925","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/ALN.0000000000001429","article-title":"Does dexmedetomidine have a perineural mechanism of action when used as an adjuvant to ropivacaine?: A paired, blinded, randomized trial in healthy volunteers","volume":"126","author":"Andersen","year":"2017","journal-title":"Anesthesiology"},{"key":"R14-20250925","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/0970-9185.202196","article-title":"Efficacy of dexmedetomidine with ropivacaine in supraclavicular brachial plexus block for upper limb surgeries","volume":"33","author":"Chinnappa","year":"2017","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"R15-20250925","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1007\/s11605-017-3402-5","article-title":"Effect of adding dexmedetomidine to ropivacaine on ultrasound-guided dual transversus abdominis plane block after gastrectomy","volume":"21","author":"Ding","year":"2017","journal-title":"J Gastrointest Surg"},{"key":"R16-20250925","doi-asserted-by":"crossref","first-page":"297","DOI":"10.4103\/0970-9185.83670","article-title":"Dexmedetomidine: New avenues","volume":"27","author":"Grewal","year":"2011","journal-title":"J Anaesthesiol Clin Pharmacol"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01437113-201913020-00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:40:57Z","timestamp":1787067657000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01437113-201913020-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/sja.sja_533_18","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}