{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:30Z","timestamp":1786649430933,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Malignant hyperthermia (MH) remains the monster every anesthesiologist can meet suddenly in the OR. It is a rare but life-threatening hypermetabolic reaction triggered by certain anesthetic agents. Here we present a case of a 40-year-old male, who developed MH 45 min after induction of anesthesia for functional endoscopic sinus surgery (FESS) in King Abdulaziz Medical City in KSA. It was not the first time the patient was exposed to general anesthesia, with no relevant family history. Early recognition, prompt administration of dantrolene, and aggressive supportive measures resulted in full recovery. Despite the full recovery from metabolic derangements, he developed upper extremity DVT in the same limb dantrolene was administered.<\/jats:p>","DOI":"10.4103\/sja.sja_560_25","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:01:19Z","timestamp":1767337279000},"page":"217-219","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Successful management of malignant hyperthermia with dantrolene complicated by upper limb DVT: A case report"],"prefix":"10.4103","volume":"20","author":[{"given":"Mostafa","family":"Nagy","sequence":"first","affiliation":[{"name":"Department of Anesthesia, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia"},{"name":"Research and Development, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"},{"name":"Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia"},{"name":"Department of Anesthesia and Critical Care Medicine, Cairo University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Nasir","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia"},{"name":"Research and Development, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"},{"name":"Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayan","family":"Muawad","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia"},{"name":"Research and Development, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"},{"name":"Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed H.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia"},{"name":"Research and Development, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"},{"name":"Medical Education, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"AlDhuwaihy","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"R1-20260421","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13023-015-0310-1","article-title":"Malignant 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crisis: Guidelines from the European malignant hyperthermia group","volume":"105","author":"Glahn","year":"2010","journal-title":"Br J Anaesth"},{"key":"R11-20260421","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1111\/ene.12713","article-title":"RYR1-related myopathies: a wide spectrum of phenotypes throughout life","volume":"22","author":"Snoeck","year":"2015","journal-title":"Eur J Neurol"},{"key":"R12-20260421","first-page":"417","article-title":"Deep vein thrombosis associated with dantrolene use","volume":"115","author":"Grodofsky","year":"2011","journal-title":"Anesthesiology"},{"key":"R13-20260421","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/00000542-199803000-00006","article-title":"The sensitivity and specificity of the caffeine-halothane contracture test: A report from the North American malignant hyperthermia registry","volume":"88","author":"Allen","year":"1998","journal-title":"Anesthesiology"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_560_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:54:02Z","timestamp":1786647242000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_560_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/sja.sja_560_25","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-07-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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