{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:35Z","timestamp":1787761955391,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>ABSTRACT<\/jats:title>\n                    <jats:p>Based on brain magnetic resonance imaging results, the second and third most frequent causes of central pontine myelinolysis (CPM) were liver transplant (LT) and cirrhosis, which together accounted for 13.7% and 12.5% of all diagnoses of CPM. Medical diseases including cirrhosis, LT, malnutrition, and alcoholism are well-known conditions associated with CPM in addition to hyponatremia. The prognosis is poor and depends on early diagnosis and treatment to achieve better outcomes. This is a case report of CPM occurring after a deceased donor LT in a patient presenting many risk factors such as chronic hyponatremia, previous episodes of encephalopathy, and tacrolimus immunosuppression. We briefly discuss the pathophysiology, risk factors, diagnosis, and treatment, highlighting the role and challenges of the anesthesiologist in managing this kind of patient and preventing the syndrome in the context of major surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sja.sja_709_22","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T22:42:22Z","timestamp":1678401742000},"page":"275-277","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Central pontine myelinolysis after liver transplant"],"prefix":"10.4103","volume":"17","author":[{"given":"Francisco","family":"Biagio Murta e Di Flora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio Vitor","family":"Machado Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Henrique Torres Menezes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Ayres","family":"Delgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-25-20240909","doi-asserted-by":"crossref","first-page":"bcr2013203516","DOI":"10.1136\/bcr-2013-203516","article-title":"Central pontine myelinolysis: Electrolytes and beyond","volume":"2014","author":"Mascarenhas","year":"2014","journal-title":"BMJ Case Rep"},{"key":"R2-25-20240909","first-page":"e3252","article-title":"Normal correction of sodium leading to central pontine demyelinosis: A rare occurrence","volume":"10","author":"Siddiqui","year":"2018","journal-title":"Cureus"},{"key":"R3-25-20240909","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1097\/TP.0000000000000496","article-title":"Risk factors for central pontine and extrapontine myelinolysis after liver transplantation: A single-center study","volume":"99","author":"Crivellin","year":"2015","journal-title":"Transplantation"},{"key":"R4-25-20240909","first-page":"600","article-title":"Central pontine myelinosis and osmotic demyelination syndrome","volume":"116","author":"Lambeck","year":"2019","journal-title":"Dtsch Arztebl Int"},{"key":"R5-25-20240909","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/petr.12255","article-title":"Central pontine myelinolysis following pediatric living donor liver transplantation: A case report and review of literature","volume":"18","author":"Uchida","year":"2014","journal-title":"Pediatr Transplant"},{"key":"R6-25-20240909","first-page":"e8209","article-title":"Osmotic demyelination syndrome despite appropriate hyponatremia correction","volume":"12","author":"Jahan","year":"2020","journal-title":"Cureus"},{"key":"R7-25-20240909","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.jceh.2021.07.011","article-title":"Tacrolimus-induced central pontine myelinolysis in a pediatric liver transplant recipient","volume":"12","author":"Patel","year":"2022","journal-title":"J Clin Exp Hepatol"},{"key":"R8-25-20240909","first-page":"326","article-title":"Is central pontine myelinolysis reversible?","volume":"115","author":"Rebedew","year":"2016","journal-title":"Wis Med J"},{"key":"R9-25-20240909","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.transproceed.2020.01.144","article-title":"Anesthetic fluid management of patients with hyponatremia undergoing living donor liver transplantation","volume":"52","author":"Wang","year":"2020","journal-title":"Transplant Proc"},{"key":"R10-25-20240909","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1111\/ajt.14317","article-title":"Prevention of the osmotic demyelination syndrome after liver transplantation: A multidisciplinary perspective","volume":"17","author":"Crismale","year":"2017","journal-title":"Am J Transplant"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_709_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:09:06Z","timestamp":1787760546000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_709_22"}},"subtitle":["A case report and an updated review"],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/sja.sja_709_22","relation":{},"ISSN":["1658-354X"],"issn-type":[{"value":"1658-354X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}