{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:28:32Z","timestamp":1787228912842,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 15-year-old boy with a severe phenotype of Glutaric Acidemia Type 1 (GA-1) presented for planned major thoracolumbar scoliosis correction under general anesthesia. Propofol is relatively contraindicated in patients with GA-1 according to latest guidance because of the risk of propofol infusion syndrome. Because of previous use of propofol in the patient when admitted to intensive care and the potential benefits as a sleep agent we decided to use propofol for his surgery and postoperative sedation. We report the successful use of propofol for general anesthesia and postoperative sedation on intensive care.<\/jats:p>","DOI":"10.4103\/sja.sja_935_25","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:01:18Z","timestamp":1782968478000},"page":"695-697","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Total intravenous anesthesia with propofol and remifentanil followed by planned sedation with propofol alone in Intensive care for a patient with glutaric acidemia type-1 undergoing complex thoracolumbar scoliosis surgery"],"prefix":"10.4103","volume":"20","author":[{"given":"Jonathan","family":"Mathers","sequence":"first","affiliation":[{"name":"Department of Anesthesia, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars O.","family":"Sandnes","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Haukeland University Hospital, Bergen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"key":"R1-20260820","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0006-2944(75)90091-5","article-title":"Glutaric aciduria;a \u00abnew\u00bbdisorder of amino acid metabolism","volume":"12","author":"Goodman","year":"1975","journal-title":"Biochem Med"},{"key":"R2-20260820","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/(SICI)1098-1004(1998)12:3<141::AID-HUMU1>3.0.CO;2-K","article-title":"Glutaryl-CoA dehydrogenase mutations in glutaric acidemia (type I): Review and report of thirty novel mutations","volume":"12","author":"Goodman","year":"1998","journal-title":"Hum Mutat"},{"key":"R3-20260820","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1023\/B:BOLI.0000045769.96657.af","article-title":"Neonatal screening for glutaryl-CoA dehydrogenase deficiency","volume":"27","author":"Lindner","year":"2004","journal-title":"J Inherit Metab Dis"},{"key":"R5-20260820","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.jcma.2014.06.010","article-title":"Anesthetic management of comprehensive dental restoration in a child with glutaric aciduria type 1 using volatile sevoflurane","volume":"77","author":"Teng","year":"2014","journal-title":"J Chin Med Assoc"},{"key":"R6-20260820","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00540-010-1083-2","article-title":"The child with glutaric aciduria type I: Anesthetic and perioperative management","volume":"25","author":"Tsiotou","year":"2011","journal-title":"J Anesth"},{"key":"R7-20260820","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1460-9592.2005.01629.x","article-title":"Anesthetic management in two siblings with glutaris aciduria type 1","volume":"16","author":"Hernandez-Palazon","year":"2006","journal-title":"Pediatr Anaesth"},{"key":"R8-20260820","first-page":"e66612","article-title":"Remimazolam anesthesia for a pediatric patient with glutaric aciduria type 1: A case report","volume":"16","author":"Tsuruno","year":"2014","journal-title":"Cureus"},{"key":"R9-20260820","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jclinane.2012.06.023","article-title":"The peripartum management of a patient with glutaric aciduria type 1","volume":"25","author":"Ituk","year":"2013","journal-title":"J Clin Anesth"},{"key":"R10-20260820","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1097\/00000539-200212000-00020","article-title":"Bispectral index monitoring: A comparison between normal children and children with quadriplegic cerebral palsy","volume":"95","author":"Choudry","year":"2002","journal-title":"Anesth Analg"}],"container-title":["Saudi Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_935_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:01:35Z","timestamp":1787227295000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sja.sja_935_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/sja.sja_935_25","relation":{},"ISSN":["1658-354X","0975-3125"],"issn-type":[{"value":"1658-354X","type":"print"},{"value":"0975-3125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2025-11-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}