{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:14Z","timestamp":1787762054069,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Methods that minimize the time for on-site bowel preparation before colonoscopy are needed. We prospectively validated that a novel algorithm-based active cleansing (ABAC) protocol could reduce the time for preparation compared with the conventional method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was an open-label, multicenter, prospective comparative study from April to October 2021. The study compared the bowel preparation time for colonoscopy between patients instructed with the ABAC protocol and control groups. Patients in the ABAC protocol group as well as the control group were administered 2000 mL of polyethylene glycol (PEG) within 2 hours. After the first two hours, patients in the protocol group voluntarily took 300 ml of the solution without the instruction of nursing staff depending on the number of defecations in the first 2 hours. The intervention and control groups were adjusted for background characteristics by propensity score matching (PSM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      After adjustment by PSM, 174 patients in each of the two groups were included in the final analysis. In the intention-to-treat analysis, the preparation time was significantly shorter in the intervention group than that in the control group (126.3 \u00b1 32.7 min vs. 144.9 \u00b1 39.9 min,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.018). The proportion of additional PEG intake was significantly higher in the intervention group (16 [9.2%] vs. 6 [3.4%],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.047). The number of defecations was also higher in the intervention group than in the control group (7.8 \u00b1 2.5 vs. 6.3 \u00b1 2.2,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Simple active instruction protocol is effective to reduce on-site bowel preparation time and nursing staff labor for colonoscopy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjg.sjg_176_23","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T07:08:05Z","timestamp":1689750485000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["An algorithm-based active cleansing protocol can reduce the bowel preparation time for screening colonoscopy: A propensity score matching study"],"prefix":"10.4103","volume":"30","author":[{"given":"Fumiaki","family":"Ishibashi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan"},{"name":"Koganei Tsurukame Clinic, Endoscopy Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Mirraza Shinjuku Tsurukame Clinic, Tokyo, Japan"},{"name":"Shinjuku Tsurukame Clinic, Digestive Disease Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konomi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Koganei Tsurukame Clinic, Endoscopy Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Kawakami","sequence":"additional","affiliation":[{"name":"Koganei Tsurukame Clinic, Endoscopy Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuki","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Mochida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Morishita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1056\/NEJM199304013281301","article-title":"Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. 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