{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:45:48Z","timestamp":1786718748013,"version":"build-2736575974"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Saudi J Gastroenterol"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4103\/sjg.sjg_29_18","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T09:25:26Z","timestamp":1528104326000},"page":"294","source":"Crossref","is-referenced-by-count":6,"title":["The role of the PLR\u2013NLR combination in the prediction of the presence of Helicobacter pylori and its associated complications"],"prefix":"10.4103","volume":"24","author":[{"given":"Mustafa","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihsan","family":"Ates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmut","family":"Yuksel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MehmetF","family":"Arikan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulden","family":"Aydog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesrin","family":"Turhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkan","family":"G\u00f6kbulut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ertugrul","family":"Kayacetin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1319-3767.233791-1","first-page":"123","volume-title":"Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori","author":"Eaton","year":"1992","journal-title":"J Med Microbiol"},{"key":"key-10.4103\/1319-3767.233791-2","first-page":"239","volume-title":"Helicobacter pylori eradication in patients with immune thrombocytopenic purpura: A review and the role of biogeography","author":"Frydman","year":"2015","journal-title":"Helicobacter"},{"key":"key-10.4103\/1319-3767.233791-3","first-page":"2818","volume-title":"Helicobacter pylori and mean platelet volume: A relation way before immune thrombocytopenia?","author":"Umit","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"key-10.4103\/1319-3767.233791-4","first-page":"1671","volume-title":"Inflammation, infection, and cardiovascular risk: How good is the clinical evidence?","author":"Ridker","year":"1998","journal-title":"Circulation"},{"key":"key-10.4103\/1319-3767.233791-5","doi-asserted-by":"crossref","unstructured":"Kalia N, Jacob S, Brown NJ, Reed MW, Morton D, Bardhan KD. Studies on the gastric mucosal microcirculation. 2. Helicobacter pylori water soluble extracts induce platelet aggregation in the gastric mucosal microcirculation in vivo. Gut 1997;41:748-52.","DOI":"10.1136\/gut.41.6.748"},{"key":"key-10.4103\/1319-3767.233791-6","first-page":"996","volume-title":"Platelet activation In mice and human Helicobacter pylori infection","author":"Elizalde","year":"1997","journal-title":"J Clin Invest"},{"key":"key-10.4103\/1319-3767.233791-7","first-page":"15","volume-title":"Thromboxane biosynthesis and metabolism in relation to cardiovascular risk factors","author":"Patrono","year":"1992","journal-title":"Trends Cardiovasc Med"},{"key":"key-10.4103\/1319-3767.233791-8","first-page":"246","volume-title":"Helicobacter pylori infection causes persistent platelet activation in vivo through enhanced lipid peroxidation","author":"Davi","year":"2005","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key-10.4103\/1319-3767.233791-9","first-page":"13","volume-title":"Platelet interactions in thrombosis","author":"Andrews","year":"2004","journal-title":"IUBMB Life"},{"key":"key-10.4103\/1319-3767.233791-10","first-page":"271","volume-title":"Activation of ADP receptors and platelet function","author":"Gachet","year":"1997","journal-title":"Thromb Haemost"},{"key":"key-10.4103\/1319-3767.233791-11","first-page":"289","volume-title":"A method for investigating the role of calcium in the shape change, aggregation and serotonin release of rat platelets","author":"Belville","year":"1979","journal-title":"J Physiol"},{"key":"key-10.4103\/1319-3767.233791-12","first-page":"630","volume-title":"Association between high platelet indices and proteinuria in patients with hypertension","author":"Ates","year":"2015","journal-title":"Ann Lab Med"},{"key":"key-10.4103\/1319-3767.233791-13","first-page":"1161","volume-title":"Classification and grading of gastritis: The updated Sydney system","author":"Dixon","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"key-10.4103\/1319-3767.233791-14","doi-asserted-by":"crossref","unstructured":"Hosmer DW, Lemeshow S. Interpretation of the fitted logistic regression model. In: Shewhart WA, Wilks SS, editors. Applied Logistic Regression, 2nd ed. New York, NY: Wiley; 2000. p. 47-90.","DOI":"10.1002\/0471722146"},{"key":"key-10.4103\/1319-3767.233791-15","first-page":"1443","volume-title":"Helicobacter pylori infection with intestinal metaplasia: An independent risk factor for colorectal adenomas","author":"Yan","year":"2017","journal-title":"World J Gastroenterol"},{"key":"key-10.4103\/1319-3767.233791-16","first-page":"1","volume-title":"Analyzing the influence of gastric intestinal metaplasia on gastric ulcer healing in Helicobacter pylori-infected patients without atrophic gastritis","author":"Chen","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"key-10.4103\/1319-3767.233791-17","first-page":"1311","volume-title":"Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance","author":"Liu","year":"2016","journal-title":"World J Gastroenterol"},{"key":"key-10.4103\/1319-3767.233791-18","first-page":"E311","volume-title":"Endoscopic atrophic classification before and after H.pylori eradication is closely associated with histological atrophy and intestinal metaplasia","author":"Kodama","year":"2015","journal-title":"EndoscInt Open"},{"key":"key-10.4103\/1319-3767.233791-19","first-page":"717","volume-title":"Chronic gastritis and its association with H.pylori infection","author":"Fatema","year":"2015","journal-title":"Mymensingh Med J"},{"key":"key-10.4103\/1319-3767.233791-20","first-page":"605","volume-title":"The association between Helicobacter pylori gastritis and lymphoid aggregates, lymphoid follicles and intestinal metaplasia in gastric mucosa of children","author":"Kara","year":"2014","journal-title":"J Paediatr Child Health"},{"key":"key-10.4103\/1319-3767.233791-21","first-page":"129","volume-title":"Antral atrophy, intestinal metaplasia, and preneoplastic markers in Mexican children with Helicobacter pylori-positive and Helicobacter pylori-negative gastritis","author":"Villarreal-Calderon","year":"2014","journal-title":"Ann Diagn Pathol"},{"key":"key-10.4103\/1319-3767.233791-22","first-page":"770","volume-title":"Regression of gastric intestinal metaplasia after the eradication of Helicobacter pylori infection in a hospital in Mexico","author":"Sanchez","year":"2016","journal-title":"Rev Esp Enferm Dig"},{"key":"key-10.4103\/1319-3767.233791-23","first-page":"120","volume-title":"Serum TNF-a, IL-8, VEGF levels in Helicobacter pylori infection and their association with degree of gastritis","author":"Siregar","year":"2015","journal-title":"Acta Med Indones"},{"key":"key-10.4103\/1319-3767.233791-24","doi-asserted-by":"crossref","unstructured":"Farah R, Hamza H, Khamisy-Farah R. A link between platelet to lymphocyte ratio and Helicobacter pylori infection. J Clin Lab Anal 2018;32.","DOI":"10.1002\/jcla.22222"},{"key":"key-10.4103\/1319-3767.233791-25","first-page":"726","volume-title":"The relationship between mean platelet volume levels and the inflammation in Helicobacter pylori gastritis","author":"Topal","year":"2010","journal-title":"J Nal Med Assoc"},{"key":"key-10.4103\/1319-3767.233791-26","first-page":"172","volume-title":"Helicobacter pylori upregulates peripheral platelet counts mainly in female patients","author":"Matsukawa","year":"2011","journal-title":"Acta Haematol"},{"key":"key-10.4103\/1319-3767.233791-27","first-page":"52","volume-title":"Helicobacter pylori eradication reduces platelet count in patients without idiopathic thrombocytopenic purpura","author":"Matsukawa","year":"2007","journal-title":"Platelets"}],"container-title":["Saudi Journal of Gastroenterology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:39:15Z","timestamp":1786714755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjg.SJG_29_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018]]}},"alternative-id":["233791"],"URL":"https:\/\/doi.org\/10.4103\/sjg.sjg_29_18","relation":{},"ISSN":["1319-3767"],"issn-type":[{"value":"1319-3767","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}