{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:28:52Z","timestamp":1787776132942,"version":"build-2784847793"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n Transjugular intrahepatic portosystemic shunt (TIPS) is the main method to prevent the rebleeding of esophagogastric varices. Many studies have demonstrated that pre-emptive TIPS (p-TIPS) is superior to medicine combined with endoscopic standard therapy in the efficacy of high-risk patients, but very few relevant studies reported whether p-TIPS is more effective than elective TIPS. This study aims to compare the efficacy and prognosis of p-TIPS and elective TIPS for the treatment of esophagogastric variceal bleeding (EGVB) patients with cirrhosis.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n In this retrospective study, clinical data of 92 patients with cirrhosis who accepted TIPS treatment after EGVB of cirrhosis were collected. According to the different times of TIPS, the patients were divided into the p-TIPS group and the elective TIPS group. The following information is documented: clinical manifestations and laboratory examination at 1, 3, and 6 months after the operation, survival state, the rates of rebleeding at 6 weeks and 6 months, and postoperative complications and serious adverse events during follow-up.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The Child-Pugh score (\n P<\/jats:italic>\n = 0.002) and MELD score (\n P<\/jats:italic>\n = 0.006) in the p-TIPS group were significantly lower than those in the elective TIPS group in the 6\n th<\/jats:sup>\n month after treatment. The rate of no gastric coronary vein embolization in the p-TIPS group was higher than in the elective TIPS group (\n P<\/jats:italic>\n = 0.034). The hospitalized days (\n P<\/jats:italic>\n < 0.001) and hospitalized costs (\n P<\/jats:italic>\n < 0.001) were significantly lower in the p-TIPS group than in the elective TIPS group. No significant differences were observed between the two groups concerning rebleeding, overt hepatic encephalopathy, ascites, complications, and serious adverse events, occurrence.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The p-TIPS contributes to liver function recovery and enhances patient survival benefits at 6-months postoperation in the treatment of EGVB compared with elective TIPS, without increasing the incidence of complications and adverse events.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/sjg.sjg_389_24","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T07:00:11Z","timestamp":1738911611000},"page":"168-175","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative efficacy of pre-emptive TIPS and elective TIPS in EGVB patients with cirrhosis: A single-center retrospective study"],"prefix":"10.4103","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2348-4216","authenticated-orcid":false,"given":"Jinfeng","family":"Ren","sequence":"first","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9850-8506","authenticated-orcid":false,"given":"Tianyu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Sichuan, China"},{"name":"Department of Digestive Endoscopy Center, Suining Central Hospital, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6551-5329","authenticated-orcid":false,"given":"Zhengying","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2164-631X","authenticated-orcid":false,"given":"Xihui","family":"Yuan","sequence":"additional","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5170-450X","authenticated-orcid":false,"given":"Minyuan","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"R1-20250519","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1185\/03007995.2015.1021905","article-title":"Presentation and complications associated with cirrhosis of the liver","volume":"31","author":"Poordad","year":"2015","journal-title":"Curr Med Res Opin"},{"key":"R2-20250519","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1097\/MEG.0000000000001686","article-title":"PTFE-covered TIPS is an effective treatment for secondary preventing variceal rebleeding in cirrhotic patients with high risks","volume":"32","author":"Zhou","year":"2020","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"R3-20250519","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1053\/j.gastro.2013.10.018","article-title":"AMELD-based model to determine risk of mortality among patients with acute variceal bleeding","volume":"146","author":"Reverter","year":"2014","journal-title":"Gastroenterology"},{"key":"R4-20250519","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.cgh.2009.08.011","article-title":"Predicting early mortality after acute variceal hemorrhage based on classification and regression tree analysis","volume":"7","author":"Augustin","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"R5-20250519","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.3390\/diagnostics13061031","article-title":"Diagnosis and management of esophagogastric varices","volume":"13","author":"Pallio","year":"2023","journal-title":"Diagnostics"},{"key":"R6-20250519","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1055\/a-1939-4887","article-title":"Endoscopic diagnosis and management of esophagogastric variceal hemorrhage:European Society of Gastrointestinal Endoscopy (ESGE) Guideline","volume":"54","author":"Gralnek","year":"2022","journal-title":"Endoscopy"},{"key":"R7-20250519","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"European Association for the Study of the Liver Electronic address:easloffice@easloffice.eu, European Association for the Study of the Liver. 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