{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:02:09Z","timestamp":1787169729096,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Aim:<\/jats:title>\n                    <jats:p>Dyspepsia has a significant impact on the quality of life. Health-related quality of life (HRQoL) can be assessed by disease-specific and generic HRQoL instruments. The present study evaluated HRQoL and compared it among dyspepsia subgroups by using EQ (Euro QoL)-5D questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Patients with abnormal findings on upper gastrointestinal endoscopy were classified to have organic dyspepsia, whereas those with normal endoscopy were classified as functional dyspepsia if they met the ROME III criteria or as endoscopy negative recent dyspepsia if symptom duration was &lt;6 months. HRQoL was assessed using the EQ-5D questionnaire, and the overall health status on a visual analogue scale (VAS); and the frequency of impairment in each dimension were compared between the dyspepsia subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The overall health status was affected equally in all three dyspepsia subgroups. Impairment in HRQoL was commonly seen in the dimensions of pain (98.4%), usual activities (66.20%), and anxiety\/depression (70.60%), however, much less so in mobility (22.70%) and self-care (10.9%). Any impairment in HRQoL was not significantly different between the three subgroups in the dimensions of mobility and usual activities. Self-care was more commonly affected in organic dyspepsia, anxiety\/depression was more common with functional dyspepsia, while pain, though significantly different among various subgroups, was very common in all three subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>HRQoL was equally affected in all three subgroups of dyspepsia but variably so in the different domains of EQ-5D. These differences need to be studied further to improve the management of different etiological subgroups of dyspepsia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjg.sjg_487_16","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T06:55:36Z","timestamp":1680072936000},"page":"112-116","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Quality of Life in Dyspepsia and its Subgroups Using EQ-5D (EuroQol) Questionnaire"],"prefix":"10.4103","volume":"23","author":[{"given":"Anurag J.","family":"Shetty","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girisha","family":"Balaraju","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiran","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cannanore G.","family":"Pai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250523","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1007\/s10620-014-3243-y","article-title":"Prevalence of uninvestigated dyspepsia and gastroesophageal reflux disease in Korea: A population-based study using the Rome III criteria","volume":"59","author":"Min","year":"2014","journal-title":"Dig Dis Sci"},{"key":"R2-20250523","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1136\/gut.31.4.401","article-title":"Dyspepsia in England and Scotland","volume":"31","author":"Jones","year":"1990","journal-title":"Gut"},{"issue":"Suppl 4","key":"R3-20250523","first-page":"iv10","article-title":"Clinical and economic consequences of dyspepsia in the community","volume":"50","author":"Moayyedi","year":"2002","journal-title":"Gut"},{"key":"R4-20250523","doi-asserted-by":"crossref","first-page":"43","DOI":"10.5056\/jnm.2012.18.1.43","article-title":"Economic impact of dyspepsia in rural and urban Malaysia: A population-based study","volume":"18","author":"Mahadeva","year":"2012","journal-title":"J Neurogastroenterol Motil"},{"key":"R5-20250523","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/1471-230X-14-149","article-title":"Health related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: A longitudinal study","volume":"14","author":"Wen","year":"2014","journal-title":"BMC Gastroenterol"},{"key":"R6-20250523","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1471-230X-9-20","article-title":"The EQ-5D (Euroqol) is a valid generic instrument for measuring quality of life in patients with dyspepsia","volume":"9","author":"Mahadeva","year":"2009","journal-title":"BMC Gastroenterol"},{"key":"R7-20250523","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"The EuroQol Group. EuroQol-a new facility for the measurement of health-related quality of life","volume":"16","year":"1990","journal-title":"Health Policy"},{"key":"R8-20250523","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1053\/j.gastro.2005.11.059","article-title":"Functional Gastroduodenal Disorders","volume":"130","author":"Tack","year":"2006","journal-title":"Gastroenterology"},{"key":"R11-20250523","doi-asserted-by":"crossref","first-page":"e0115838","DOI":"10.1371\/journal.pone.0115838","article-title":"The Impact of Dyspepsia on Symptom Severity and Quality of Life in Adults with Headache","volume":"10","author":"Tai","year":"2015","journal-title":"PLoS One"},{"key":"R12-20250523","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1111\/j.1365-2036.2010.04270.x","article-title":"Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban Malaysia","volume":"31","author":"Mahadeva","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"R13-20250523","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/ajg.2010.26","article-title":"Risk factors associated with dyspepsia in a rural Asian population and its impact on quality of life","volume":"105","author":"Mahadeva","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"R15-20250523","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/01.PSY.0000075977.90337.E7","article-title":"Medically unexplained physical symptoms, anxiety, and depression: A meta-analytic review","volume":"65","author":"Henningsen","year":"2003","journal-title":"Psychosom Med"},{"key":"R16-20250523","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1136\/gut.2008.158162","article-title":"Determinants of symptoms in functional dyspepsia: Gastric sensorimotor function, psychosocial factors or somatization?","volume":"57","author":"Van","year":"2008","journal-title":"Gut"},{"key":"R17-20250523","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5056\/jnm.2012.18.1.13","article-title":"Psychological Co-morbidity in Functional Gastrointestinal Disorders: Epidemiology, Mechanisms and Management","volume":"18","author":"Wu","year":"2012","journal-title":"J Neurogastroenterol Motil"},{"key":"R18-20250523","doi-asserted-by":"crossref","first-page":"52","DOI":"10.5056\/jnm.2010.16.1.52","article-title":"Validation of Self-administrated Questionnaire for Psychiatric Disorders in Patients with Functional Dyspepsia","volume":"16","author":"Tse","year":"2010","journal-title":"J Neurogastroenterol Motil"},{"key":"R19-20250523","doi-asserted-by":"crossref","first-page":"e102320","DOI":"10.1371\/journal.pone.0102320","article-title":"Epidemiology of Functional Abdominal Bloating and Its Impact on Health Related Quality of Life: Male-Female Stratified Propensity Score Analysis in a Population Based Survey in Mainland China","volume":"9","author":"Wu","year":"2014","journal-title":"PLoS One"}],"container-title":["Saudi Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00936815-201723020-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:11:41Z","timestamp":1787166701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00936815-201723020-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/sjg.sjg_487_16","relation":{},"ISSN":["1319-3767","1998-4049"],"issn-type":[{"value":"1319-3767","type":"print"},{"value":"1998-4049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"2016-09-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}