{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:00:42Z","timestamp":1787169642998,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The purpose of this study is to assess patients\u2019 compliance to recommendations after evaluation of pancreatic cystic neoplasm (PCN) with EUS and investigate how the presence of \u201cworrisome\u201d characteristics including cyst's size, main pancreatic duct dilation and presence of mural nodules might affect the adherence rates of management recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study of patients at a private tertiary hospital who were referred for evaluation with EUS over a 5-year period (2015-2019), after the diagnosis of pancreatic cystic neoplasm during radiological imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We included 111 patients (mean age 64.1 years, SD = 13.9) with PCN. After the EUS examination, 16 patients were referred for surgical resection, 4 patients needed no further follow up and 91 patients were recommended to follow imaging surveillance. In total, 70 (63.1%) subjects adhered to surveillance recommendations. In the group of subjects who adhered to surveillance, cyst size \u22653cm was found in 27 (38.6%) patients, main pancreatic duct diameter \u22655mm in 12 (17.1%) subjects and only 3 (4.3%) pancreatic cysts demonstrated mural nodules. However, none of the aforementioned cystic \u201cworrisome features\u201d was significantly correlated with increased adherence to follow up (p = 0.709,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.642 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.630, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Although the majority of patients with PCN adhered to given recommendations after EUS examination, the number of noncompliant subjects was noticeable. The presence of cystic \u201cworrisome\u201d features did not correlate with an increased compliance rate to suggested management plan. Further prospective studies are needed to elucidate the factors that may enhance patients\u2019 adherence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjg.sjg_505_21","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T07:12:59Z","timestamp":1644217979000},"page":"122-126","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pancreatic cystic neoplasms"],"prefix":"10.4103","volume":"28","author":[{"given":"Athanasios","family":"Sioulas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Spinou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Schizas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Megapanou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximos","family":"Frountzas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantina","family":"Papadaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Scotiniotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240829","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.pan.2018.11.014","article-title":"Systematic review and meta-analysis: Prevalence of incidentally detected pancreatic cystic lesions in asymptomatic individuals","volume":"19","author":"Zerboni","year":"2019","journal-title":"Pancreatology"},{"key":"R2-7-20240829","doi-asserted-by":"crossref","first-page":"e5535","DOI":"10.1097\/MD.0000000000005535","article-title":"Incidental pancreatic cystic neoplasms in an asymptomatic healthy population of 21,745 individuals: Large-scale, single-center cohort study","volume":"95","author":"Chang","year":"2016","journal-title":"Medicine (Baltimore"},{"key":"R3-7-20240829","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/gutjnl-2016-313127","article-title":"Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study","volume":"67","author":"Kromrey","year":"2018","journal-title":"Gut"},{"key":"R4-7-20240829","doi-asserted-by":"crossref","first-page":"47","DOI":"10.5858\/arpa.2019-0308-RA","article-title":"Cystic lesions of the pancreas: Differential diagnosis and cytologic-histologic correlation","volume":"144","author":"Abdelkader","year":"2020","journal-title":"Arch Pathol Lab Med"},{"key":"R5-7-20240829","doi-asserted-by":"crossref","first-page":"413","DOI":"10.4103\/1947-2714.139298","article-title":"Pancreatic cystic neoplasms","volume":"6","author":"Limaiem","year":"2014","journal-title":"N Am J Med Sci"},{"key":"R7-7-20240829","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.pan.2017.07.007","article-title":"Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas","volume":"17","author":"Tanaka","year":"2017","journal-title":"Pancreatology"},{"key":"R8-7-20240829","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1053\/j.gastro.2015.01.015","article-title":"American Gastroenterology Association, American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts","volume":"148","author":"Vege","year":"2015","journal-title":"Gastroenterology"},{"key":"R9-7-20240829","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s10620-018-5368-x","article-title":"Survey study on the practice patterns of the evaluation and management of incidental pancreatic cysts","volume":"64","author":"Westerveld","year":"2019","journal-title":"Dig Dis Sci"},{"key":"R10-7-20240829","doi-asserted-by":"crossref","first-page":"e000430","DOI":"10.1136\/bmjgast-2020-000430","article-title":"Factors affecting the rates of adherence to surveillance recommendations for incidental pancreatic cystic lesions in a large urban safety net hospital","volume":"7","author":"Canakis","year":"2020","journal-title":"BMJ Open Gastroenterol"},{"key":"R11-7-20240829","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1097\/MPA.0000000000001352","article-title":"The surveillance patterns of incidentally detected pancreatic cysts vary widely and infrequently adhere to guidelines","volume":"48","author":"Schenck","year":"2019","journal-title":"Pancreas"},{"key":"R12-7-20240829","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1097\/MPA.0000000000000747","article-title":"Are clinical guidelines for the management of intraductal papillary mucinous neoplasms followed.: A single-center analysis?","volume":"46","author":"Tabrizian","year":"2017","journal-title":"Pancreas"},{"key":"R13-7-20240829","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.pan.2020.01.006","article-title":"Psychological distress in patients under surveillance for intraductal papillary mucinous neoplasms of the pancreas: The \u201cSword of Damocles\u201d effect calls for an integrated medical and psychological approach a prospective analysis","volume":"20","author":"Marinelli","year":"2020","journal-title":"Pancreatology"},{"key":"R14-7-20240829","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4103\/eus.eus_56_19","article-title":"Quality of life impact of EUS in patients at risk for developing pancreatic cancer","volume":"9","author":"Cazacu","year":"2020","journal-title":"Endosc Ultrasound"},{"key":"R15-7-20240829","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10897-008-9205-9","article-title":"Pancreatic cancer surveillance among high-risk populations: Knowledge and intent","volume":"18","author":"Lewis","year":"2009","journal-title":"J Genet Couns"}],"container-title":["Saudi Journal of 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