{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:48:41Z","timestamp":1786736921875,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Saudi J Gastroenterol"],"published-print":{"date-parts":[[2020]]},"DOI":"10.4103\/sjg.sjg_626_19","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T04:35:38Z","timestamp":1586838938000},"page":"84","source":"Crossref","is-referenced-by-count":10,"title":["Efficacy of a bismuth-based quadruple therapy regimen for Helicobacter pylori eradication in Saudi Arabia"],"prefix":"10.4103","volume":"26","author":[{"given":"Fahad","family":"Alsohaibani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alquaiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"Alkahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamad","family":"Alashgar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musthafa","family":"Peedikayil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"AlFadda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Almadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/1319-3767.283935-1","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1200\/JCO.2014.59.7344","article-title":"GI stromal tumors: 15 years of lessons from a rare cancer","author":"Cioffi","year":"2015","journal-title":"J Clin Oncol"},{"key":"key-10.4103\/1319-3767.283935-2","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1056\/NEJM200104053441404","article-title":"Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor","author":"Joensuu","year":"2001","journal-title":"N Engl J Med"},{"key":"key-10.4103\/1319-3767.283935-3","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1200\/JCO.2008.20.4818","article-title":"Imatinib plasma levels are correlated with clinical benefit in patients with unresectable\/metastatic gastrointestinal stromal tumors","author":"Demetri","year":"2009","journal-title":"J Clin Oncol"},{"key":"key-10.4103\/1319-3767.283935-4","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.critrevonc.2008.09.007","article-title":"Gastrointestinal stromal tumour in the elderly","author":"Tham","year":"2009","journal-title":"Crit Rev Oncol Hematol"},{"key":"key-10.4103\/1319-3767.283935-5","first-page":"536","article-title":"Soft tissue sarcoma, Version 2.2018, NCCN clinical practice guidelines in oncology","author":"von","year":"2018","journal-title":"J Natl Compr Canc Netw"},{"key":"key-10.4103\/1319-3767.283935-6","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1158\/1535-7163.MCT-18-0498","article-title":"Association of imatinib plasma concentration and single nucleotide polymorphisms with adverse drug reactions in patients with gastrointestinal stromal tumors","author":"Zhang","year":"2018","journal-title":"Mol Cancer Ther"},{"key":"key-10.4103\/1319-3767.283935-7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1080\/00365521.2019.1577488","article-title":"Intracellular concentration and transporters in imatinib resistance of gastrointestinal stromal tumor","author":"Zhang","year":"2019","journal-title":"Scand J Gastroenterol"},{"key":"key-10.4103\/1319-3767.283935-8","unstructured":"Recamier JCA. L'histoire de le Meme Maladie. Gabor; 1829. p. 110."},{"key":"key-10.4103\/1319-3767.283935-9","first-page":"1","article-title":"Cancer cells in the circulating blood; a clinical study on the occurrence of cancer cells in the peripheral blood and in venous blood draining the tumour area at operation","author":"Engell","year":"1955","journal-title":"Acta Chir Scand Suppl"},{"key":"key-10.4103\/1319-3767.283935-10","doi-asserted-by":"crossref","unstructured":"Gay L, Baker AM, Graham TA. Tumour cell heterogeneity. F1000Res 2016;5. doi: 10.12688\/f1000research. 7210.1","DOI":"10.12688\/f1000research"},{"key":"key-10.4103\/1319-3767.283935-11","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.drudis.2018.11.017","article-title":"Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: Myth or reality?","author":"Brown","year":"2019","journal-title":"Drug Discov Today"},{"key":"key-10.4103\/1319-3767.283935-12","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/1878-0261.12081","article-title":"Cancer metastasis through the prism of epithelial-to-mesenchymal transition in circulating tumor cells","author":"Micalizzi","year":"2017","journal-title":"Mol Oncol"},{"key":"key-10.4103\/1319-3767.283935-13","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1053\/j.gastro.2018.09.020","article-title":"Detection and analysis of circulating epithelial cells in liquid biopsies from patients with liver disease","author":"Bhan","year":"2018","journal-title":"Gastroenterology"},{"key":"key-10.4103\/1319-3767.283935-14","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.cell.2012.06.035","article-title":"The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites","author":"Gao","year":"2012","journal-title":"Cell"},{"key":"key-10.4103\/1319-3767.283935-15","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1093\/annonc\/mdn786","article-title":"Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer","author":"Cohen","year":"2009","journal-title":"Ann Oncol"},{"key":"key-10.4103\/1319-3767.283935-16","first-page":"6302","article-title":"Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer","author":"de","year":"2008","journal-title":"Clin Cancer Res"},{"key":"key-10.4103\/1319-3767.283935-17","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1093\/carcin\/bgx030","article-title":"Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research","author":"Pang","year":"2017","journal-title":"Carcinogenesis"},{"key":"key-10.4103\/1319-3767.283935-18","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/annonc\/mdw535","article-title":"Circulating tumour cells and pathological complete response: Independent prognostic factors in inflammatory breast cancer in a pooled analysis of two multicentre phase II trials (BEVERLY-1 and -2) of neoadjuvant chemotherapy combined with bevacizumab","author":"Pierga","year":"2017","journal-title":"Ann Oncol"},{"key":"key-10.4103\/1319-3767.283935-19","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1158\/1078-0432.CCR-05-2821","article-title":"Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival","author":"Hayes","year":"2006","journal-title":"Clin Cancer Res"},{"key":"key-10.4103\/1319-3767.283935-20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3322\/caac.21388","article-title":"The eighth edition AJCC cancer staging manual: Continuing to build a bridge from a population-based to a more \u201cpersonalized\u201d approach to cancer staging","author":"Amin","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"key-10.4103\/1319-3767.283935-21","doi-asserted-by":"crossref","first-page":"36645","DOI":"10.18632\/oncotarget.9128","article-title":"Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: A prospective study","author":"Li","year":"2016","journal-title":"Oncotarget"},{"key":"key-10.4103\/1319-3767.283935-22","doi-asserted-by":"crossref","first-page":"e1420450","DOI":"10.1080\/2162402X.2017.1420450","article-title":"Cell-surface vimentin-positive macrophage-like circulating tumor cells as a novel biomarker of metastatic gastrointestinal stromal tumors","author":"Li","year":"2018","journal-title":"Oncoimmunology"},{"key":"key-10.4103\/1319-3767.283935-23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0002-9440(10)64706-2","article-title":"Isolation by size of epithelial tumor cells: A new method for the immunomorphological and molecular characterization of circulatingtumor cells","author":"Vona","year":"2000","journal-title":"Am J Pathol"},{"key":"key-10.4103\/1319-3767.283935-24","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.humpath.2008.06.025","article-title":"Risk stratification of patients diagnosed with gastrointestinal stromal tumor","author":"Joensuu","year":"2008","journal-title":"Hum Pathol"},{"key":"key-10.4103\/1319-3767.283935-25","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s41571-019-0187-3","article-title":"Liquid biopsy and minimal residual disease - Latest advances and implications for cure","author":"Pantel","year":"2019","journal-title":"Nat Rev Clin Oncol"},{"key":"key-10.4103\/1319-3767.283935-26","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1158\/1535-7163.MCT-17-0436","article-title":"Clinical application of circulating tumor DNA in the genetic analysis of patients with advanced GIST","author":"Xu","year":"2018","journal-title":"Mol Cancer Ther"},{"key":"key-10.4103\/1319-3767.283935-27","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.tranon.2019.06.005","article-title":"Building CT radiomics-based models for preoperatively predicting malignant potential and mitotic count of gastrointestinal stromal tumors","author":"Wang","year":"2019","journal-title":"Transl Oncol"},{"key":"key-10.4103\/1319-3767.283935-28","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1126\/science.1228522","article-title":"Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition","author":"Yu","year":"2013","journal-title":"Science"},{"key":"key-10.4103\/1319-3767.283935-29","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.cell.2014.07.013","article-title":"Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis","author":"Aceto","year":"2014","journal-title":"Cell"},{"key":"key-10.4103\/1319-3767.283935-30","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1126\/science.aaf6546","article-title":"A collective route to metastasis: Seeding by tumor cell clusters","author":"Cheung","year":"2016","journal-title":"Science"}],"container-title":["Saudi Journal of Gastroenterology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:47:52Z","timestamp":1786733272000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjg.SJG_626_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"alternative-id":["282504"],"URL":"https:\/\/doi.org\/10.4103\/sjg.sjg_626_19","relation":{},"ISSN":["1319-3767"],"issn-type":[{"value":"1319-3767","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]}}}