{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:59:18Z","timestamp":1792641558801,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To observe and preliminarily evaluate the efficacy and safety of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) in the treatment of non-ampullary duodenal lesions (NADLs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective observational study included 84 patients who underwent endoscopic resection (ER) with non-ampullary duodenal lesions, between March 2010 and November 2020, at the Cancer Hospital of the Chinese Academy of Medical Sciences (Beijing, China). Data on patient demographics, therapeutic outcomes, and follow-up results were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There were 44 patients undergoing EMR, and 40 patients accepting ESD. The overall en bloc resection rate was 98.8% (83\/84). For the neoplastic lesions, the overall en bloc resection rate and curative rate were 98.5% (67\/68) and 89.7% (61\/68), respectively. The procedure-related bleeding and perforation rates were 2.4% and 10.7%, respectively. Univariate analysis results indicated that the main correlation factor of non-curative pathologic resection was tumor size (p = 0.004) and resection size (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01). There showed a higher curative rate in patients with tumors less than 25 mm in diameter. Multivariate logistic regression analyses determined that the tumor size (OR 0.935; 95% CI 0.878-0.995;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.035) was associated with non-curative resection. No recurrences were observed in patients who had undergone a complete ER during a follow-up period of 42.8 months (range, 3-127 months).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Endoscopic resection is an effective, safe, and feasible treatment for non-ampullary duodenal lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjg.sjg_646_20","type":"journal-article","created":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T02:09:23Z","timestamp":1613095763000},"page":"302-308","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["The value of endoscopic resection for non-ampullary duodenal lesions"],"prefix":"10.4103","volume":"27","author":[{"given":"Zhengqi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhou","family":"Dou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiqing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xudong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoiloi","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240829","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3748\/wjg.v22.i2.600","article-title":"Approach to the endoscopic resection of duodenal lesions","volume":"22","author":"Gaspar","year":"2016","journal-title":"World J Gastroenterol"},{"key":"R2-7-20240829","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/den.12104","article-title":"Delayed perforation: A hazardous complication of endoscopic resection for non-ampullary duodenal neoplasm","volume":"26","author":"Inoue","year":"2014","journal-title":"Digest Endosc"},{"key":"R3-7-20240829","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/den.13485","article-title":"Differentiation between duodenal neoplasms and non-neoplasms using magnifying narrow-band imaging \u2013 Do we still need biopsies for duodenal lesions?","volume":"32","author":"Yamasaki","year":"2020","journal-title":"Digest Endosc"},{"key":"R4-7-20240829","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/den.13475","article-title":"Future of endoscopy: Brief review of current and future endoscopic resection techniques for colorectal lesions","volume":"32","author":"Hossain","year":"2020","journal-title":"Digest Endosc"},{"key":"R5-7-20240829","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1007\/s00464-019-06918-4","article-title":"Factors associated with conversion to snare resection during gastric endoscopic submucosal dissection","volume":"34","author":"Kim","year":"2020","journal-title":"Surg Endosc"},{"key":"R6-7-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10388-014-0465-1","article-title":"Guidelines for diagnosis and treatment of carcinoma of the esophagus April 2012 edited by the Japan Esophageal Society","volume":"12","author":"Kuwano","year":"2015","journal-title":"Esophagus"},{"key":"R7-7-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10147-017-1101-6","article-title":"Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer","volume":"23","author":"Watanabe","year":"2018","journal-title":"Int J Clin Oncol"},{"key":"R9-7-20240829","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.gie.2015.06.027","article-title":"The role of endoscopy in ampullary and duodenal adenomas","volume":"82","author":"Chathadi","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"R10-7-20240829","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1007\/s00464-016-5200-7","article-title":"Endoscopic resection for duodenal subepithelial tumors: A single-center experience","volume":"31","author":"Kim","year":"2017","journal-title":"Surg Endosc"},{"key":"R11-7-20240829","doi-asserted-by":"crossref","first-page":"5474","DOI":"10.3748\/wjg.v16.i43.5474","article-title":"Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions","volume":"16","author":"Jung","year":"2010","journal-title":"World J Gastroenterol"},{"key":"R12-7-20240829","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/den.12273","article-title":"Therapeutic outcomes of endoscopic resection for superficial non-ampullary duodenal tumor","volume":"26","author":"Yamamoto","year":"2014","journal-title":"Dig Endosc"},{"key":"R13-7-20240829","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000452363","article-title":"Endoscopic submucosal dissection and endoscopic mucosal resection for non-ampullary superficial duodenal tumor","volume":"95","author":"Hoteya","year":"2017","journal-title":"Digestion"},{"key":"R14-7-20240829","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1159\/000459619","article-title":"The risk factors for metastasis in non-ampullary duodenal neuroendocrine tumors measuring 20 mm or less in diameter","volume":"95","author":"Hatta","year":"2017","journal-title":"Digestion"},{"key":"R15-7-20240829","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1080\/00365521.2018.1438508","article-title":"Endoscopic mucosal resection of non-ampullary sporadic duodenal adenomas: A retrospective analysis with long-term follow-up","volume":"53","author":"Valerii","year":"2018","journal-title":"Scand J Gastroenterol"},{"key":"R16-7-20240829","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1159\/000496697","article-title":"Assessment of duodenal adenomas and strategies for curative therapy","volume":"37","author":"Pavlovic-Markovic","year":"2019","journal-title":"Dig Dis"},{"key":"R17-7-20240829","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1111\/jgh.14640","article-title":"The clinicopathological differences of sporadic non-ampullary duodenal epithelial neoplasm depending on tumor location","volume":"34","author":"Matsueda","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"R18-7-20240829","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/den.12377","article-title":"Delayed bleeding after endoscopic submucosal dissection for non-ampullary superficial duodenal neoplasias might be prevented by prophylactic endoscopic closure: Analysis of risk factors","volume":"27","author":"Hoteya","year":"2015","journal-title":"Dig Endosc"},{"key":"R19-7-20240829","first-page":"8","article-title":"Duodenal endoscopic submucosal dissection is feasible using the pocket-creation method","volume":"49","author":"Miura","year":"2017","journal-title":"Endoscopy"},{"key":"R20-7-20240829","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/jgh.12390","article-title":"Endoscopic resection for duodenal carcinoid tumors: A multicenter, retrospective study","volume":"29","author":"Kim","year":"2014","journal-title":"J Gastroenterol Hepatol"},{"key":"R21-7-20240829","first-page":"423","article-title":"Value of endoscopic resection on duodenal space-occupying lesions","volume":"34","author":"Wu","year":"2017","journal-title":"Chin J Dig Endosc"}],"container-title":["Saudi Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sjg.sjg_646_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:40:25Z","timestamp":1787845225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjg.sjg_646_20"}},"subtitle":["A single-center experience"],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/sjg.sjg_646_20","relation":{},"ISSN":["1319-3767"],"issn-type":[{"value":"1319-3767","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]}}}