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In conclusion, in cases of profound vision loss with no obvious cause, neuroimaging should be performed to evaluate the orbital extent of the disease and exclude intracranial pathology.<\/jats:p>","DOI":"10.4103\/sjopt.sjopt_109_22","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T06:00:07Z","timestamp":1708495207000},"page":"185-187","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Rare presentation of orbital metastasis in multiple myeloma"],"prefix":"10.4103","volume":"38","author":[{"given":"Charles","family":"O\u2019Donovan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Royal Eye Unit, Kingston Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela D.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Eye Unit, Kingston Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei S.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Eye Unit, Kingston Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"R1-20260507","article-title":"Guidelines for the Diagnosis and Management of Multiple Myeloma 2014","author":"Bird","year":"2014"},{"key":"R2-20260507","doi-asserted-by":"crossref","first-page":"e538","DOI":"10.1016\/S1470-2045(14)70442-5","article-title":"International myeloma working group updated criteria for the diagnosis of multiple myeloma","volume":"15","author":"Rajkumar","year":"2014","journal-title":"Lancet Oncol"},{"key":"R3-20260507","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4274\/tjo.73645","article-title":"Orbital metastasis of multiple myeloma: Case report","volume":"46","author":"Vatansever","year":"2016","journal-title":"Turk J Ophthalmol"},{"key":"R5-20260507","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/BF00176888","article-title":"Plasmacytoma of the eye and orbit","volume":"20","author":"Adkins","year":"1996","journal-title":"Int Ophthalmol"},{"key":"R6-20260507","doi-asserted-by":"crossref","first-page":"831","DOI":"10.3109\/10428190109099349","article-title":"Primary extramedullary plasmacytoma of the lacrimal gland","volume":"42","author":"Chim","year":"2001","journal-title":"Leuk Lymphoma"},{"key":"R7-20260507","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1001\/archopht.1972.01000020032006","article-title":"Orbital involvement in multiple myeloma. 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