{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:22:19Z","timestamp":1787764939754,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>Squamous cell carcinoma (SCC) arising from the orbit is a rare entity. Only a dozen of such cases are reported in the literature. Owing to its rarity, standard treatment is not defined, but most are treated with surgery. Herewith, we report the case of primary orbital SCC, in a 56-year-old female treated with radiotherapy (RT) alone, who presented with features of left-sided painful blind eye of 4 months\u2019 duration. Clinical and imaging studies pointed to no other possible primary malignancy elsewhere in the body, and a final diagnosis of locally advanced primary orbital SCC was made. The patient was treated with intensity-modulated RT, to a total dose of 66Gy in 33 fractions and completed the treatment with good pain relief. Response assessment imaging showed a complete response to treatment. At 2-year follow-up, the patient is alive, without disease and with normal vision in the unaffected eye. To conclude, primary orbital SCC is rare and can be treated successfully with RT.<\/jats:p>","DOI":"10.4103\/sjopt.sjopt_11_23","type":"journal-article","created":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T23:15:57Z","timestamp":1702250157000},"page":"256-259","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Primary orbital squamous cell carcinoma treated with definitive radiotherapy"],"prefix":"10.4103","volume":"37","author":[{"given":"Sapna","family":"Krishnamurthy","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, JNMC and KLES Dr. Prabhakar Kore Hospital and MRC KAHER, Belgaum, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imtiaz","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, JNMC and KLES Dr. Prabhakar Kore Hospital and MRC KAHER, Belgaum, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.ophtha.2003.01.002","article-title":"Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1","volume":"111","author":"Shields","year":"2004","journal-title":"Ophthalmology"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1001\/archopht.1984.01040031296011","article-title":"Classification and incidence of space-occupying lesions of the orbit. 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