{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:00:51Z","timestamp":1790402451211,"version":"4.1.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>To compare the outcomes of fibrin glue versus sutures in pterygium surgery with amniotic membrane transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A systematic review and meta-analysis were performed as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses Guidelines. An electronic search identified all studies comparing the outcomes of using fibrin glue versus sutures in pterygium surgery with amniotic membrane transplantation. Conjunctival inflammation, postoperative pain and discomfort, pterygium recurrence, pyogenic granuloma, and surgical time were primary outcome measures. Secondary outcome measures included amniotic membrane transplant outcomes, time to recurrence, graft loss, and subconjunctival hemorrhage. Fixed and random-effects models were used for the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Four studies enrolling 180 patients were identified. Conjunctival inflammation (odds ratio [OR] 0.21,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0005) demonstrated a significant difference favoring the fibrin glue group. Despite the trend favoring the use of fibrin glue, there were no significant differences in terms of postoperative pain and discomfort (OR = 0.46,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.25), pterygium recurrence (OR = 0.74,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.48), pyogenic granuloma (OR = 0.47,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.38), and surgical time (mean difference = \u221217.52,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.13). For secondary outcomes, fibrin glue had significantly fewer cases of graft loss compared with sutures. No statistically significant difference was found in amniotic membrane graft outcomes, time to recurrence, and subconjunctival hemorrhage.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Fibrin glue is comparable to the sutures used in pterygium surgery with amniotic membrane transplantation as it significantly improves conjunctival inflammation and does not increase postoperative pain and discomfort, pterygium recurrence, pyogenic granuloma, and surgical time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjopt.sjopt_143_22","type":"journal-article","created":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T23:19:54Z","timestamp":1702250394000},"page":"83-89","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["The use of fibrin glue in pterygium surgery with amniotic membrane transplantation: Systematic review and meta-analysis"],"prefix":"10.4103","volume":"37","author":[{"given":"Mohammad","family":"Karam","sequence":"first","affiliation":[{"name":"AlBahar Ophthalmology Center, Ibn Sina Hospital, Ministry of Health, West Midlands, UK,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulmalik","family":"Alsaif","sequence":"additional","affiliation":[{"name":"Department of Surgery, Walsall Healthcare NHS Trust, West Midlands, UK,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Aldubaikhi","sequence":"additional","affiliation":[{"name":"Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"},{"name":"Department of Radiology, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meshaal","family":"Aljebreen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rand","family":"Alazaz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Almudhaiyan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia"},{"name":"Division of Ophthalmology, National Guard Hospital, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"AlBaghli","sequence":"additional","affiliation":[{"name":"AlBahar Ophthalmology Center, Ibn Sina Hospital, Ministry of Health, West Midlands, UK,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"R1-20240830","first-page":"82","article-title":"Prevalence and risk factors of pterygium","volume":"2","author":"L\u00fc","year":"2009","journal-title":"Int J Ophthalmol"},{"key":"R2-20240830","first-page":"78","article-title":"Current concepts in management of pterygium","volume":"25","author":"Bahuva","year":"2015","journal-title":"Delhi J Ophthalmol"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/01.icu.0000172827.31985.3a","article-title":"Amniotic membrane use in ophthalmology","volume":"16","author":"Gomes","year":"2005","journal-title":"Curr Opin Ophthalmol"},{"key":"R4-20240830","first-page":"23","article-title":"Amniotic membrane transplantation for primary pterygium surgery","volume":"3","author":"Katbaab","year":"2008","journal-title":"J Ophthalmic Vis 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Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_143_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:53:35Z","timestamp":1787763215000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_143_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,9]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/sjopt.sjopt_143_22","relation":{},"ISSN":["1319-4534","2542-6680"],"issn-type":[{"value":"1319-4534","type":"print"},{"value":"2542-6680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,9]]},"assertion":[{"value":"2022-08-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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