{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:22:19Z","timestamp":1787764939726,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:p>We report a rare association of unilateral keratoconus (KC) and iridocorneal endothelial syndrome in a 34-year-old female. Slit-lamp examination showed advanced KC with faint apical scarring in her right eye. The pupil was superiorly displaced with superior peripheral anterior synechia. Specular microscopy showed abnormal endothelium with low endothelial cell count in the right eye. Corneal topography confirmed the unilateral KC diagnosis. As the patient did not tolerate hard contact lens, penetrating keratoplasty with pupilloplasty was performed with excellent outcome.<\/jats:p>","DOI":"10.4103\/sjopt.sjopt_159_22","type":"journal-article","created":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T23:19:54Z","timestamp":1702250394000},"page":"164-166","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Unilateral keratoconus associated with iridocorneal endothelial syndrome: Case report"],"prefix":"10.4103","volume":"37","author":[{"given":"Hatem A.","family":"Kalantan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,6,26]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"763093","DOI":"10.1155\/2015\/763093","article-title":"Diagnosis and management of iridocorneal endothelial syndrome","volume":"2015","author":"Sacchetti","year":"2015","journal-title":"Biomed Res Int"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1186\/s12886-019-1215-x","article-title":"Iridocorneal endothelial syndrome in a patient with keratoconus \u2013A case report","volume":"19","author":"De Maria","year":"2019","journal-title":"BMC Ophthalmol"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/00003226-199205000-00012","article-title":"Bilateral progressive essential iris atrophy and keratoconus with coincident features of posterior polymorphous dystrophy:A case report and proposed pathogenesis","volume":"11","author":"Blair","year":"1992","journal-title":"Cornea"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"68","DOI":"10.5935\/0004-2749.20190014","article-title":"Posterior keratoconus and iris atrophy:A fortuitous association?","volume":"82","author":"Gus","year":"2019","journal-title":"Arq Bras Oftalmol"},{"key":"R6-20240830","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4103\/ijo.IJO_986_15","article-title":"A unique case of keratoconus with Cogan-Reese syndrome and secondary glaucoma","volume":"65","author":"Chakrabarty","year":"2017","journal-title":"Indian J Ophthalmol"},{"key":"R7-20240830","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1136\/bjo.61.12.761","article-title":"Keratoconus and coexisting atopic disease","volume":"61","author":"Rahi","year":"1977","journal-title":"Br J Ophthalmol"},{"key":"R8-20240830","first-page":"243","article-title":"Keratoconus and blindness in 469 institutionalised subjects with Down syndrome and other causes of mental retardation","volume":"25","author":"Walsh","year":"1981","journal-title":"J Ment Defic Res"},{"key":"R9-20240830","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/01.ico.0000137168.24883.3e","article-title":"Eye rubbing can cause keratoconus","volume":"23","author":"Krachmer","year":"2004","journal-title":"Cornea"},{"key":"R10-20240830","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.mehy.2017.10.023","article-title":"Etiological mechanism of iridocorneal endothelial (ICE) syndrome may involve infection of herpes simplex virus (HSV) and integration of viral genes into human genome","volume":"110","author":"Li","year":"2018","journal-title":"Med Hypotheses"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_159_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:53:19Z","timestamp":1787763199000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_159_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/sjopt.sjopt_159_22","relation":{},"ISSN":["1319-4534","2542-6680"],"issn-type":[{"value":"1319-4534","type":"print"},{"value":"2542-6680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2022-09-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}