{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:32:48Z","timestamp":1787841168620,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>Speciality contact lenses are utilized for both ocular surface disorders and refractive error corrections. Common and widely used among them are large corneal rigid gas permeable lenses such as corneo-scleral and mini-scleral lenses. These lenses are designed to rest on the conjunctival tissue overlying the sclera to create a vault over the entire cornea and limbus. The lenses fit in and settle into conjunctival tissue, compressing the collector channels and episcleral veins, directly affecting the aqueous outflow. Consequently, an increase in intraocular pressure (IOP) is anticipated. This study aims to determine the effect of large corneal lens wear over IOP. This included evaluation of IOP variations, corneal thickness variations, and topographic changes before and after large corneal rigid gas permeable lens wear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>An interventional study was performed on 30 subjects who had attended the outpatient department of the institute and undergone ophthalmic and medical examinations along with contact lens fitting tests. IOP, corneal thickness, and corneal curvature measurements were captured before and immediately following 6 h of lens wear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>The average value of intra-ocular pressure before wearing lenses was 11.77 \u00b1 1.77 mmHg and after wearing corneoscleral lenses was 12.17 \u00b1 1.96 mmHg and mini-scleral lens was 12.03 \u00b1 1.92 mmHg. Average values of central corneal thickness (CCT) before wearing lenses were 531.07 \u00b1 20.58 \u03bcm and after wearing were 537.33 \u00b1 20.68 \u03bcm for corneo-scleral lens and 540.60 \u00b1 20.30 \u03bcm for mini-scleral lens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>There was substantial increase in intra-ocular pressure and CCT after wearing both corneo-scleral lens and mini-scleral lens for 6 h. There were no significant changes seen in corneal curvature after wearing both lenses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjopt.sjopt_189_24","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T08:00:39Z","timestamp":1731916839000},"page":"52-56","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Intraocular pressure variation associated with the wear of large corneal rigid gas permeable lenses"],"prefix":"10.4103","volume":"40","author":[{"given":"U.","family":"Roopa","sequence":"first","affiliation":[{"name":"Department of Optometry, Little Flower Institute of Medical Science and Research, Kerala University of Health Sciences, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathews G.","family":"Vadath","sequence":"additional","affiliation":[{"name":"Department of Optometry, Little Flower Institute of Medical Science and Research, Kerala University of Health Sciences, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visakh G.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Optometry, College of Applied Medical Sciences, Qassim University, Ministry of Higher Education, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Chacko","sequence":"additional","affiliation":[{"name":"Department of Optometry, Little Flower Institute of Medical Science and Research, Kerala University of Health Sciences, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash V.","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Department of Optometry, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"R2-20260416","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/ICL.0000000000000214","article-title":"Intraocular pressure after 2 hours of small-diameter scleral lens wear","volume":"42","author":"Nau","year":"2016","journal-title":"Eye Contact Lens"},{"key":"R3-20260416","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/ICL.0000000000000670","article-title":"Effect of scleral lens wear on central corneal thickness and intraocular pressure in patients with ocular surface disease","volume":"46","author":"Shahnazi","year":"2020","journal-title":"Eye Contact Lens"},{"key":"R4-20260416","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.22374\/jclrs.v3i1.34","article-title":"Influence of scleral lens on intraocular pressure","volume":"3","author":"Aitsebaomo","year":"2019","journal-title":"J Contact Lens Res 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influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population","volume":"41","author":"Lafosse","year":"2018","journal-title":"Cont Lens Anterior Eye"},{"key":"R9-20260416","first-page":"12","article-title":"Physiologic changes of the cornea with contact lens wear","volume":"28","author":"Liesegang","year":"2002","journal-title":"Eye Contact Lens"},{"key":"R10-20260416","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/opo.12270","article-title":"Mini-scleral lens wear influences corneal curvature and optics","volume":"36","author":"Vincent","year":"2016","journal-title":"Ophthalmic Physiol Opt"},{"key":"R11-20260416","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.clae.2014.02.002","article-title":"Modern scleral contact lenses: A review","volume":"37","author":"van der Worp","year":"2014","journal-title":"Cont Lens Anterior Eye"},{"key":"R12-20260416","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.clae.2018.07.004","article-title":"Intra-ocular pressure variation associated with the wear of scleral lenses of different diameters","volume":"42","author":"Michaud","year":"2019","journal-title":"Cont Lens Anterior Eye"},{"key":"R13-20260416","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/cxo.12368","article-title":"A hypothesis that scleral contact lenses could elevate intraocular pressure","volume":"99","author":"McMonnies","year":"2016","journal-title":"Clin Exp Optom"},{"key":"R14-20260416","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1080\/02713683.2018.1500610","article-title":"Central corneal edema with scleral-lens wear","volume":"43","author":"Kim","year":"2018","journal-title":"Curr Eye Res"},{"key":"R15-20260416","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.clae.2014.08.002","article-title":"Corneal changes following short-term miniscleral contact lens wear","volume":"37","author":"Vincent","year":"2014","journal-title":"Cont Lens Anterior Eye"},{"key":"R16-20260416","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.clae.2018.06.005","article-title":"Anterior eye surface changes following miniscleral contact lens wear","volume":"42","author":"Consejo","year":"2019","journal-title":"Cont Lens Anterior Eye"}],"container-title":["Saudi Journal of 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