{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:04Z","timestamp":1787772304823,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>An iris cyst is a nonkeratinized squamous epithelial-lined space involving a layer of iris. The presentation of iris cyst can be variable-innocuous or presenting with secondary complications. The identification of whether the cyst is primary or secondary is important. The prognosis of primary iris cysts is good, as the majority does not require treatment and that of secondary iris cysts is much more capricious depending on their presentation. Their optimal management often poses a challenge for ophthalmologists. Here, we will present two cases of iris cysts with diverse presentation along with a review of the literature of this rare clinical entity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjopt.sjopt_228_21","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T05:31:05Z","timestamp":1716183065000},"page":"341-346","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Iris cysts"],"prefix":"10.4103","volume":"35","author":[{"given":"Suneeta","family":"Dubey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Pegu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanika","family":"Jain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240830","first-page":"771","article-title":"Primary cysts of the iris","volume":"79","author":"Shields","year":"1981","journal-title":"Trans Am Ophthalmol Soc"},{"key":"R2-11-20240830","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/bjo.68.3.152","article-title":"Primary iris cysts: A review of the literature and report of 62 cases","volume":"68","author":"Shields","year":"1984","journal-title":"Br J Ophthalmol"},{"key":"R3-11-20240830","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/S0161-6420(98)91034-X","article-title":"Primary cysts of the iris pigment epithelium. Clinical features and natural course in 234 patients","volume":"105","author":"Lois","year":"1998","journal-title":"Ophthalmology"},{"key":"R4-11-20240830","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ophtha.2011.07.059","article-title":"Clinical survey of 3680 iris tumors based on patient age at presentation","volume":"119","author":"Shields","year":"2012","journal-title":"Ophthalmology"},{"key":"R5-11-20240830","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1136\/bjo.71.3.227","article-title":"Congenital iris cysts","volume":"71","author":"Grutzmacher","year":"1987","journal-title":"Br J Ophthalmol"},{"key":"R6-11-20240830","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1001\/archopht.1967.00980030498016","article-title":"Spontaneous nonpigmented iris cysts","volume":"78","author":"Naumann","year":"1967","journal-title":"Arch Ophthalmol"},{"key":"R7-11-20240830","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1136\/bjo.76.1.39","article-title":"Spontaneous congenital non-pigmented epithelial cysts of the iris stroma","volume":"76","author":"Paridaens","year":"1992","journal-title":"Br J Ophthalmol"},{"key":"R8-11-20240830","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/S0161-6420(98)97041-5","article-title":"Primary iris stromal cysts. A report of 17 cases","volume":"105","author":"Lois","year":"1998","journal-title":"Ophthalmology"},{"key":"R10-11-20240830","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3928\/15428877-20090901-10","article-title":"Complete ring cyst of iris pigment epithelium documented by ultrasound biomicroscopy","volume":"40","author":"Laham","year":"2009","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"R11-11-20240830","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1136\/bjo.68.12.859","article-title":"Laser treatment of primary ring-shaped epithelial iris cyst","volume":"68","author":"Bron","year":"1984","journal-title":"Br J Ophthalmol"},{"key":"R12-11-20240830","first-page":"59","article-title":"Iris ring cyst. Case report","volume":"87","author":"Turati","year":"2013","journal-title":"Rev Mex Oftalmol"},{"key":"R13-11-20240830","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0002-9394(14)70544-6","article-title":"Echographic evaluation of primary cysts of the iris pigment epithelium","volume":"121","author":"Kozart","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"R14-11-20240830","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1001\/archopht.126.6.867","article-title":"Recurrent iris pigment epithelial cyst induced by topical prostaglandin F2\u03b1 analogues","volume":"126","author":"Krohn","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"R15-11-20240830","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0002-9394(02)01953-0","article-title":"Iris cyst secondary to latanoprost mimicking iris melanoma","volume":"135","author":"Browning","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"R17-11-20240830","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/bjophthalmol-2014-305218","article-title":"Evaluation of iris and iridociliary body lesions with anterior segment optical coherence tomography versus ultrasound B-scan","volume":"99","author":"Hau","year":"2015","journal-title":"Br J Ophthalmol"},{"key":"R18-11-20240830","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1016\/S0161-6420(99)90495-5","article-title":"Differential diagnosis of anterior segment cysts by ultrasound biomicroscopy","volume":"106","author":"Marigo","year":"1999","journal-title":"Ophthalmology"},{"key":"R19-11-20240830","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.survophthal.2017.08.009","article-title":"Iris cysts: A comprehensive review on diagnosis and treatment","volume":"63","author":"Georgalas","year":"2018","journal-title":"Surv Ophthalmol"},{"key":"R20-11-20240830","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0002-9394(02)01960-8","article-title":"Surgical management of anterior chamber epithelial cysts","volume":"135","author":"Haller","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"R21-11-20240830","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1001\/archopht.123.9.1276","article-title":"Laser photocoagulation of primary central pigment epithelial iris cysts","volume":"123","author":"Leung","year":"2005","journal-title":"Arch Ophthalmol"},{"key":"R22-11-20240830","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1016\/j.mjafi.2013.04.001","article-title":"An uncommon case of primary iris cyst managed with Nd YAG laser","volume":"71","author":"Baranwal","year":"2015","journal-title":"Med J Armed Forces India"},{"key":"R23-11-20240830","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/S0161-6420(03)00543-8","article-title":"Epithelial iris cyst treatment with intracystic ethanol irrigation","volume":"110","author":"Behrouzi","year":"2003","journal-title":"Ophthalmology"},{"key":"R24-11-20240830","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1001\/jamaophthalmol.2014.160","article-title":"Iris stromal cyst management with absolute alcohol-induced sclerosis in 16 patients","volume":"132","author":"Shields","year":"2014","journal-title":"JAMA Ophthalmol"},{"key":"R25-11-20240830","doi-asserted-by":"crossref","first-page":"164","DOI":"10.2174\/1874364101509010164","article-title":"Surgical management of post-traumatic iris cyst","volume":"9","author":"Philip","year":"2015","journal-title":"Open Ophthalmol J"},{"key":"R26-11-20240830","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1136\/bjophthalmol-2018-312738","article-title":"Surgical management of acquired implantation iris cysts: Indications, surgical challenges and outcomes","volume":"103","author":"Shanbhag","year":"2019","journal-title":"Br J Ophthalmol"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_228_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:37:21Z","timestamp":1787769441000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_228_21"}},"subtitle":["Varied presentations and review of literature"],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/sjopt.sjopt_228_21","relation":{},"ISSN":["1319-4534"],"issn-type":[{"value":"1319-4534","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}