{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:08Z","timestamp":1787772308631,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>PURPOSE:<\/jats:title>\n                    <jats:p>To report the surgical outcome of early lens aspiration, posterior chamber intraocular lens (PC IOL), and capsular tension ring (CTR) in a case series of microspherophakia (MSP) and secondary glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Case series of 18 eyes of MSP cases presented with lenticular myopia and secondary glaucoma that underwent early lens aspiration, PC IOL and CTR by one ophthalmologist. Baseline, long-term postoperative outcomes and complications were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      All cases underwent successful surgery with lens aspiration PC IOL implantation and CTR insertion without intraoperative complications. One of the 18 cases was a delayed referral which had broad anterior synechiae and following lens aspiration developed corneal decompensation. In one eye, CTR implantation was not possible hence, lens aspiration with scleral fixation (SF) of 3 piece IOL was performed (excluded from the analysis). Overall there was an improvement in visual acuity (from 0.3 \u00b1 0.1 to 0.2 \u00b1 0.2 LogMar,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.006), intraocular pressure (IOP), and most notably, deepening of the anterior chamber. Some cases required subsequent glaucoma surgery to control IOP. After a long duration of follow-up, all cases had stable capsular lens complex and no capsular phimosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Early Lens aspiration with CTR and PCIOL alone in MSP with lens subluxation has a significant impact on the patient's quality of vision, deepening the anterior chamber and preventing complications or poor outcomes. In addition, good capsular-lens complex stability and absence of capsular phimosis or phacodonesis on long-term follow-up were obtained.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/sjopt.sjopt_231_21","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T06:28:13Z","timestamp":1716186493000},"page":"163-170","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Early lens aspiration with posterior chamber intraocular lens and capsular tension ring in microspherophakia to avoid lens-induced complications"],"prefix":"10.4103","volume":"36","author":[{"given":"Ali A.","family":"Al-Rajhi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enmar M.","family":"Almazyad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20240830","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1097\/j.jcrs.0000000000000334","article-title":"Diagnosis and treatment of microspherophakia","volume":"46","author":"Yu","year":"2020","journal-title":"Cataract Refract Surg"},{"key":"R2-8-20240830","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.ajhg.2009.09.011","article-title":"Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature","volume":"85","author":"Morales","year":"2009","journal-title":"Am J Hum Genet"},{"key":"R3-8-20240830","first-page":"1040","article-title":"Challenges in diagnosing microspherophakia in a pediatric patient","volume":"4","author":"Bitar","year":"2016","journal-title":"JSM Ophthalmol"},{"key":"R4-8-20240830","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1136\/bjophthalmol-2015-307298","article-title":"The efficacy of lens removal plus IOL implantation for the treatment of spherophakia with secondary glaucoma","volume":"100","author":"Yang","year":"2016","journal-title":"Br J Ophthalmol"},{"key":"R5-8-20240830","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1136\/bjophthalmol-2017-310861","article-title":"Outcomes of lensectomy and risk factors for failure in spherophakic eyes with secondary glaucoma","volume":"102","author":"Rao","year":"2018","journal-title":"Br J Ophthalmol"},{"key":"R6-8-20240830","doi-asserted-by":"crossref","first-page":"596","DOI":"10.4103\/0301-4738.129787","article-title":"Scleral-fixated intraocular lens implantation in microspherophakia","volume":"62","author":"Subbiah","year":"2014","journal-title":"Indian J Ophthalmol"},{"key":"R7-8-20240830","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/eye.2017.229","article-title":"Clinical spectrum and surgical outcomes in spherophakia: A prospective interventional study","volume":"32","author":"Khokhar","year":"2018","journal-title":"Eye (Lond"},{"key":"R8-8-20240830","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.clae.2012.06.003","article-title":"Capsular tension segment in a case of microspherophakia","volume":"35","author":"Khokhar","year":"2012","journal-title":"Cont Lens Anterior Eye"},{"key":"R10-8-20240830","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3928\/01913913-20110614-01","article-title":"Lenticular abnormalities in children","volume":"49","author":"Khokhar","year":"2012","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"R12-8-20240830","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/eye.2014.250","article-title":"Visual outcome and incidence of glaucoma in patients with microspherophakia","volume":"29","author":"Muralidhar","year":"2015","journal-title":"Eye (Lond"},{"key":"R13-8-20240830","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/IJG.0b013e3182707437","article-title":"Glaucoma in microspherophakia: Presenting features and treatment outcomes","volume":"23","author":"Senthil","year":"2014","journal-title":"Glaucoma"},{"key":"R14-8-20240830","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/0301-4738.58477","article-title":"Clear lens extraction and intraocular lens implantation in a case of microspherophakia with secondary angle closure glaucoma","volume":"58","author":"Bhattacharjee","year":"2010","journal-title":"Indian J Ophthalmol"},{"key":"R15-8-20240830","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/j.jcrs.0000000000000116","article-title":"Novel double-flanged technique for managing Marfan syndrome and microspherophakia","volume":"46","author":"Canabrava","year":"2020","journal-title":"Cataract Refract Surg"},{"key":"R16-8-20240830","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3126\/nepjoph.v7i1.13178","article-title":"new combined surgical approach in a patient with microspherophakia and developmental iridocorneal angle anomaly","volume":"7","author":"Satana","year":"2015","journal-title":"Nepal J Ophthalmol"},{"key":"R17-8-20240830","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jaapos.2015.02.008","article-title":"Lensectomy, vitrectomy, and transvitreal ciliary body photocoagulation as primary treatment for glaucoma in microspherophakia","volume":"19","author":"Goel","year":"2015","journal-title":"J Am Assoc Pediatr Ophthalmol Strabismus"}],"container-title":["Saudi Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_231_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:37:41Z","timestamp":1787769461000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/sjopt.sjopt_231_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/sjopt.sjopt_231_21","relation":{},"ISSN":["1319-4534"],"issn-type":[{"value":"1319-4534","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}