{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:22:26Z","timestamp":1787840546562,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Acute pancreatitis is one of the severe complications of hypertriglyceridemia, which needs to be recognized early to provide appropriate treatment. Hypertriglyceridemia-induced pancreatitis has several causes, in which\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    fertilization (IVF) is a rare etiology that is becoming increasingly popular. We report a 33-year-old female patient with a history of hypertension who has failed an IVF cycle and started a new IVF procedure 1 month before admission. She was diagnosed with severe triglyceridemia-induced acute pancreatitis with extremely high serum triglycerides (TGs) levels (18,547 mg\/dL). We combined plasmapheresis and intravenous (IV) insulin and significantly reduced blood TG over a short time. She was discharged with a TG level of 366.7 mg\/dL on the 10\n                    <jats:sup>th<\/jats:sup>\n                    day. It is essential to monitor serum TG levels in plasma before, during, and after this therapy, especially in the 1\n                    <jats:sup>st<\/jats:sup>\n                    month after initiating IVF. Although plasmapheresis combined with IV insulin is not officially recommended for acute triglyceridemia-induced pancreatitis, the therapy can be considered in cases with extremely high serum TG levels.\n                  <\/jats:p>","DOI":"10.4103\/tjem.tjem_27_24","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T17:00:15Z","timestamp":1727802015000},"page":"255-258","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review"],"prefix":"10.4103","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7613-7690","authenticated-orcid":false,"given":"Nguyen Huu","family":"Thanh","sequence":"first","affiliation":[{"name":"College of Health Sciences, VinUniversity, Ha Noi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7572-4025","authenticated-orcid":false,"given":"Trinh Van","family":"Duong","sequence":"additional","affiliation":[{"name":"College of Health Sciences, VinUniversity, Ha Noi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1025-7612","authenticated-orcid":false,"given":"Nguyen Thu","family":"Huyen","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, 108 Military Central Hospital, Ha Noi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9300-231X","authenticated-orcid":false,"given":"Pham Dang","family":"Hai","sequence":"additional","affiliation":[{"name":"Medical Intensive Care Unit, 108 Military Central Hospital, Ha Noi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"key":"R1-20241010","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1177\/2050640618755002","article-title":"Hypertriglyceridemic pancreatitis:Epidemiology, pathophysiology and clinical management","volume":"6","author":"de Pretis","year":"2018","journal-title":"United European Gastroenterol J"},{"key":"R2-20241010","first-page":"677","article-title":"Hypertriglyceridemia-induced acute pancreatitis in pregnancy","volume":"13","author":"Serpytis","year":"2012","journal-title":"JOP"},{"key":"R3-20241010","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1056\/NEJM199110243251702","article-title":"Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins","volume":"325","author":"Walsh","year":"1991","journal-title":"N Engl J Med"},{"key":"R4-20241010","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.fertnstert.2007.04.031","article-title":"The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles","volume":"89","author":"El-Toukhy","year":"2008","journal-title":"Fertil Steril"},{"key":"R5-20241010","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jacl.2022.04.002","article-title":"In vitro fertilization and hypertriglyceridemic pancreatitis:Case report","volume":"16","author":"Reddy","year":"2022","journal-title":"J Clin Lipidol"},{"key":"R6-20241010","article-title":"In vitro fertilization-induced hypertriglyceridemia with secondary acute pancreatitis and diabetic ketoacidosis","volume":"5","author":"Issa","year":"2017","journal-title":"SAGE Open Med Case Rep"},{"key":"R7-20241010","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1210\/jc.2011-3213","article-title":"Evaluation and treatment of hypertriglyceridemia:An endocrine society clinical practice guideline","volume":"97","author":"Berglund","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"R8-20241010","doi-asserted-by":"crossref","first-page":"11404","DOI":"10.1074\/jbc.275.15.11404","article-title":"Estrogen suppresses transcription of lipoprotein lipase gene. Existence of a unique estrogen response element on the lipoprotein lipase promoter","volume":"275","author":"Homma","year":"2000","journal-title":"J Biol Chem"},{"key":"R9-20241010","first-page":"890","article-title":"Recurrent pancreatitis associated with in vitro fertilization","volume":"81","author":"Steinmetz","year":"1993","journal-title":"Obstet Gynecol"},{"key":"R10-20241010","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1023\/A:1014404016609","article-title":"Severe hypertriglyceridemia and pancreatitis following hormone replacement prior to cryothaw transfer","volume":"19","author":"Ruman","year":"2002","journal-title":"J Assist Reprod Genet"},{"key":"R11-20241010","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jacl.2007.11.001","article-title":"Hypertriglyceridemia-induced pancreatitis created by oral estrogen and in vitro fertilization ovulation induction","volume":"2","author":"Lee","year":"2008","journal-title":"J Clin Lipidol"},{"key":"R12-20241010","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ejogrb.2014.04.018","article-title":"Early plasmapheresis as a successful treatment in hypertriglyceridemia-induced acute pancreatitis in first trimester pregnancy following in vitro fertilization","volume":"179","author":"Reper","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R13-20241010","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jacl.2016.12.006","article-title":"Estrogen-associated severe hypertriglyceridemia with pancreatitis","volume":"11","author":"Aljenedil","year":"2017","journal-title":"J Clin Lipidol"},{"key":"R14-20241010","doi-asserted-by":"crossref","first-page":"e05874","DOI":"10.1002\/ccr3.5874","article-title":"Hypertriglyceridemia-induced pancreatitis after egg retrieval for in vitro fertilization and fenofibrate cessation","volume":"10","author":"Shrimanker","year":"2022","journal-title":"Clin Case Rep"},{"key":"R15-20241010","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1002\/jca.21562","article-title":"Critical updates in the 7th edition of the American society for apheresis guidelines","volume":"33","author":"Ipe","year":"2018","journal-title":"J Clin Apher"},{"key":"R16-20241010","doi-asserted-by":"crossref","first-page":"870067","DOI":"10.3389\/fmed.2022.870067","article-title":"Comparable triglyceride reduction with plasma exchange and insulin in acute pancreatitis \u2013A randomized trial","volume":"9","author":"Gubensek","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"R17-20241010","doi-asserted-by":"crossref","first-page":"298","DOI":"10.17161\/kjm.vol15.17006","article-title":"Severe hypertriglyceridemia as a cause of aortic thrombus with peripheral embolic complications","volume":"15","author":"Safarova","year":"2022","journal-title":"Kans J Med"}],"container-title":["Turkish Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/tjem.tjem_27_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:48Z","timestamp":1787837088000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/tjem.tjem_27_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/tjem.tjem_27_24","relation":{},"ISSN":["2452-2473","2452-2473"],"issn-type":[{"value":"2452-2473","type":"print"},{"value":"2452-2473","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-02-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}