{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:41:13Z","timestamp":1787071273501,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:p>\n                    Diphtheria remains a serious threat and can cause life-threatening complications. We report the case of a 6-year-old girl with severe respiratory and cardiac involvement due to diphtheria. She presented with classic signs, including pseudomembrane, bull neck, lymphadenopathy, and respiratory distress.\n                    <jats:italic toggle=\"yes\">Corynebacterium diphtheriae<\/jats:italic>\n                    var. mitis with a positive toxigenic strain was confirmed. Her condition worsened, requiring intensive care admission and high-flow nasal cannula support. She later developed ventricular tachycardia with hemodynamic instability, which was successfully treated with intravenous magnesium sulfate (MgSO\n                    <jats:sub>4<\/jats:sub>\n                    ). The patient recovered with antibiotics, antitoxin, and supportive care. This case highlights the potential for severe diphtheria complications, even with timely treatment. It also suggests a possible role for MgSO\n                    <jats:sub>4<\/jats:sub>\n                    in managing diphtheria-induced arrhythmias, though further research is needed. Early diagnosis, aggressive management, and continued vaccination efforts are critical to reducing diphtheria-related morbidity and mortality.\n                  <\/jats:p>","DOI":"10.4103\/tjem.tjem_334_25","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T09:00:13Z","timestamp":1775206813000},"page":"146-149","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Lessons learned from life-threatening respiratory and cardiac complications in diphtheria: A case report and literature review"],"prefix":"10.4103","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8754-8359","authenticated-orcid":false,"given":"Tan Nicko","family":"Octora","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia"},{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1974-447X","authenticated-orcid":false,"given":"Seruni","family":"Estari","sequence":"additional","affiliation":[{"name":"Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia"},{"name":"Department of Child Health, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8829-1540","authenticated-orcid":false,"given":"Bambang Pujo","family":"Semedi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia"},{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9191-9546","authenticated-orcid":false,"given":"Dominicus","family":"Husada","sequence":"additional","affiliation":[{"name":"Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia"},{"name":"Department of Child Health, Faculty of Medicine, Airlangga University, Surabaya, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"R2-20260414","first-page":"204","article-title":"Eleven-year report of high number of diphtheria cases in children in East Java Province, Indonesia","volume":"9","author":"Husada","year":"2024","journal-title":"Trop Med Infect Dis"},{"key":"R3-20260414","doi-asserted-by":"crossref","first-page":"5769","DOI":"10.4103\/jfmpc.jfmpc_1396_20","article-title":"Diphtheritic myocarditis:A case series and review of 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