{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:18Z","timestamp":1787761938419,"version":"build-2784847793"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Melioidosis is a disease endemic to India but often goes unrecognized, leading to considerable illness and death. We present the case of a 31-year-old man who had a fever of unknown origin, abnormal renal and liver function tests, and negative tests for dengue, typhoid, leptospirosis, and scrub typhus. Imaging revealed multiple splenic infarcts. Initially suspected to be malaria due to its prevalence in South India, further investigation uncovered pneumonia along with several liver and splenic abscesses, raising the possibility of melioidosis. Blood culture eventually identified\n                    <jats:italic toggle=\"yes\">Burkholderia pseudomallei<\/jats:italic>\n                    , confirming the diagnosis. As malaria cases decline in Southeast Asia, emergency physicians should consider melioidosis in their differential diagnosis of acute febrile illnesses, especially in endemic areas. Early detection and prompt antibiotic treatment are vital for managing this often under-recognized disease with a high fatality rate. Thus, melioidosis should be considered in patients with unexplained fever in endemic regions, as early diagnosis and intervention can be life-saving.\n                  <\/jats:p>","DOI":"10.4103\/tjem.tjem_62_24","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T14:00:20Z","timestamp":1735826420000},"page":"63-66","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Melioidosis \u2013 An under-recognized dreaded disease in Southeast Asia"],"prefix":"10.4103","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2325-4719","authenticated-orcid":false,"given":"Anas Mohammed","family":"Muthanikkatt","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3286-7034","authenticated-orcid":false,"given":"Balamurugan","family":"Nathan","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0849-3447","authenticated-orcid":false,"given":"Amaravathi","family":"Uthayakumar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3498-6392","authenticated-orcid":false,"given":"Anandhi","family":"Devendiran","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3286-7034","authenticated-orcid":false,"given":"Saravanan","family":"Muthu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine and Trauma, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"R1-20250106","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1016\/S0140-6736(03)13374-0","article-title":"Melioidosis","volume":"361","author":"White","year":"2003","journal-title":"Lancet"},{"key":"R2-20250106","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0001-706X(99)00066-2","article-title":"Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and 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clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study","volume":"4","author":"Currie","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"R14-20250106","doi-asserted-by":"crossref","first-page":"17107","DOI":"10.1038\/nrdp.2017.107","article-title":"Melioidosis","volume":"4","author":"Wiersinga","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"R15-20250106","first-page":"1977","article-title":"Melioidosis: A Rare Case of Hemoptysis with Pseudoaneurysm","volume":"7","author":"Jayaprakash","year":"2016","journal-title":"Research Journal of Pharmaceutical, Biological and Chemical Sciences"},{"key":"R16-20250106","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1186\/s12916-020-01745-0","article-title":"Non-malarial febrile illness: A systematic review of published aetiological studies and case reports from Southern Asia and South-Eastern Asia, 1980-2015","volume":"18","author":"Shrestha","year":"2020","journal-title":"BMC 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