{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:18:02Z","timestamp":1790745482773,"version":"4.1.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Hematological manifestations such as anemia and thrombocytopenia are known complications in malaria. Here, we report two cases presented as pancytopenia with hepatosplenomegaly and initial diagnosis kept as hematological malignancy like leukemia but later on its diagnosed as malaria-associated hemophagocytic lymphohistiocytosis which is a rare entity. The aim of this report is to draw the attention of physicians, especially in tropical countries such as India and Sub-Saharan nations to keep in mind this uncommon presentation of malaria, though the exact pathophysiological mechanism still remains obscure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/tp.tp_34_20","type":"journal-article","created":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T03:34:50Z","timestamp":1620876890000},"page":"46-48","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Pancytopenia with hemophagocytic lymphohistiocytosis in Plasmodium falciparum"],"prefix":"10.4103","volume":"11","author":[{"given":"Shewta","family":"Chaudhry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Arya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Matlani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineeta","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam Sundar","family":"Meena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240909","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1182\/asheducation-2009.1.87","article-title":"Malaria, erythrocytic infection, and anemia","volume":"1","author":"Haldar","year":"2009","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"R2-10-20240909","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1056\/NEJMoa072727","article-title":"Severe anemia in Malawian children","volume":"358","author":"Calis","year":"2008","journal-title":"The New Engl J Med Orig"},{"key":"R3-10-20240909","first-page":"375","article-title":"Pancytopenia of unknown cause in adult patients admitted to a tertiary hospital in Ethiopia: Case series","volume":"28","author":"Gudina","year":"2018","journal-title":"Ethiop J Health Sci"},{"key":"R4-10-20240909","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/20469047.2015.1109227","article-title":"Haemophagocytic lymphohistiocytosis: A cause of unresponsive malaria in a 5-year-old girl","volume":"35","author":"Bhagat","year":"2015","journal-title":"Paediatr Int Child Health"},{"key":"R5-10-20240909","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.4269\/ajtmh.2007.76.1016","article-title":"Falciparum malaria with hemophagocytic syndrome","volume":"76","author":"Ohnishi","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"R6-10-20240909","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/S0140-6736(13)61048-X","article-title":"Adult haemophagocytic syndrome","volume":"383","author":"Ramos-Casals","year":"2014","journal-title":"Lancet"},{"key":"R7-10-20240909","doi-asserted-by":"crossref","first-page":"594","DOI":"10.4103\/0377-4929.85105","article-title":"Hemophagocytic syndrome associated with Plasmodium falciparum infection","volume":"54","author":"Vinoth","year":"2011","journal-title":"Indian J Pathol Microbiol"},{"key":"R8-10-20240909","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3126\/jnps.v30i3.3922","article-title":"Plasmodium vivax malaria complicated by neurological, jaundice and haemophagocytic syndrome","volume":"30","author":"Kumar","year":"2010","journal-title":"J Nepal Paediatr Soc"}],"container-title":["Tropical Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/tp.TP_34_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:13:54Z","timestamp":1787843634000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/tp.TP_34_20"}},"subtitle":["A unusual presentation"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/tp.tp_34_20","relation":{},"ISSN":["2229-5070"],"issn-type":[{"value":"2229-5070","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}